LY 379268

191471-52-0

CAS-Nr.: 191471-52-0

Englisch Name:: LY 379268

Synonyma:: CS-1087;LY397268;LY 379268;(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid;2-Oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid,4-amino-,(1R,4R,5S,6R)-

CBNumber:: CB5841046

Summenformel:: C7H9NO5

Molgewicht:: 187.15

MOL-Datei:: 191471-52-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 51

LY 379268 Eigenschaften

Siedepunkt:: 413.9±45.0 °C(Predicted)

Dichte: 1.716±0.06 g/cm3(Predicted)

storage temp.: Store at +4°C

Löslichkeit: Soluble in H2O or NaOH

Aggregatzustand: solid

pka: 1.81±0.40(Predicted)

Farbe: White

Wasserlöslichkeit: Soluble to 20 mM in water and to 100 mM in 1eq. NaOH

Sicherheit

LY 379268 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

LY 379268 is a group II metabotropic glutamate receptors (mGlu2/3) receptor agonist (1,2). Studies have shown that LY379268 significantly attenuated cocaine-induced increases in DA in nonhuman primates.

Biologische Aktivität

Highly selective group II mGlu receptor agonist (EC 50 values are 2.69 and 4.48 nM for hmGlu 2 and hmGlu 3 respectively) that displays > 80-fold selectivity over group I and group III receptors. Provides protection against NMDA-mediated cell death in vitro and offers almost complete protection against CA1 hippocampal damage following global ischemia in gerbils. Orally and systemically active.

LY 379268 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

LY 379268 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 51)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Ascent Scientific	4401179829988	customerservice@ascentscientific.co.uk	United Kingdom	279	60
Shanghai Witofly Chemical Co.,Ltd		sales@witofly.com	China	2867	52
Jinan Mingya Medical Technology Co., Ltd.	0531-85828981	864598798@qq.com	China	588	58
ShangHai Angti Biotechnology Co., Ltd.	13764913901	info@angtibio.com	China	4977	55
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1991	58
BOC Sciences	--	info@bocsci.com	USA	0	65

LY 379268
2-Oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid,4-amino-,(1R,4R,5S,6R)-
(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid
LY397268
CS-1087
191471-52-0
AMINOACID
Glutamate