Diethylether-Bortrifluorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R10:Entzündlich.
R14:Reagiert heftig mit Wasser.
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
R35:Verursacht schwere Verätzungen.
R48/23:Giftig: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Einatmen.
R34:Verursacht Verätzungen.
R14/15:Reagiert heftig mit Wasser unter Bildung hochentzündlicher Gase.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S8:Behälter trocken halten.
S43:Zum Löschen . . . (vom Hersteller anzugeben) verwenden (wenn Wasser die Gefahr erhöht, anfügen: "Kein Wasser verwenden").
Chemische Eigenschaften
Boron trifluoride etherates: (compounded with
methyl ether) is moisture-sensitive, corrosive, flammable liquid.
Physikalische Eigenschaften
Fuming liquid; stable at ambient temperatures but hydrolyzed on exposure to moist air; density 1.125 g/mL; refractive index 1.348; solidifies at -60.4°C; boils at 125.7°C; flash point (open cup) 147°F (68.8°C); decomposes in water.
Verwenden
Boron trifluoride diethyl etherate is used as a Lewis acid catalyst in Mukaiyama aldol addition, alkylation, acetylation, isomerization, dehydrations and condensation reactions. It is involved in the prepattion of polyethers in polymerization reactions. As a catalyst, it is used in the preparation of cyclopentyl- and cycloheptyl[b]indoles and other diborane. It is also used in sensitive neutron detectors in ionization chambers as well as monitoring radiation levels in earth?s atmosphere.
Application
Catalyst in the synthesis of polyol chains. Reagent for the coupling of imines to allylstannanes and 4′-nitrobenzenesulfenanilide to alkenes and alkynes.
Lewis acid reagent with broad application
Catalyst used in the preparation of cyclopentyl- and cycloheptyl[b]indoles from aryl cyclopropyl ketones via [3+2] cycloaddition.
synthetische
Boron trifluoride etherate is prepared by the reaction of vapors of boron trifluoride with that of anhydrous diethyl ether:
BF
3 (g) + (C
2H
5)
2O (g) → (C
2H
5)
2O?BF
3.
Allgemeine Beschreibung
Boron trifluoride etherate is a fuming liquid. Boron trifluoride etherate may be corrosive to skin, eyes and mucous membranes. Boron trifluoride etherate may be toxic by inhalation. Upon exposure to water Boron trifluoride etherate may emit flammable and corrosive vapors. Boron trifluoride etherate is used as a catalyst in chemical reactions.
Air & Water Reaktionen
Highly flammable. Fuming liquid, immediately hydrolyzed by moisture in air to form hydrogen fluoride [Merck 11th ed. 1989].
Reaktivität anzeigen
Boron trifluoride diethyl ether complex is a stable, highly flammable, colourless to brown fuming, corrosive liquid with a sharp pungent odour. It forms explosive peroxides in contact with air or oxygen. It reacts exothermically with water to form extremely flammable diethyl ether and toxic, corrosive boron trifluoride hydrates. The chemical is incompatible with bases, amines, and alkali metals. It immediately gets hydrolysed by moisture in air to form hydrogen fluoride. Boron trifluoride diethyl ether has applications in chemical laboratory as a catalyst in chemical reactions.
Hazard
The compound is highly toxic by inhalation. Skin contact causes burns.
Health Hazard
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Brandgefahr
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
mögliche Exposition
Used as a catalyst.
Versand/Shipping
Diethyl: UN2604 Boron trifluoride diethyl
etherate, Hazard class: 8; Labels: 8—Corrosive material,
3—Flammable liquid. Dimethyl: UN2965 Boron trifluoride
dimethyl etherate, Hazard class: 4.3; Labels: 4.3—
Dangerous when wet, 8—Corrosive material, 3—
Flammable liquid.
Inkompatibilitäten
Reacts with air forming corrosive hydrogen
fluoride vapors. Incompatible with oxidizers (may
cause fire and explosion), water, steam or heat, forming
corrosive and flammable vapors. Peroxide containing etherate
reacts explosively with aluminum lithium hydride,
magnesium tetrahydroaluminate. Mixtures with phenol
react explosively with 1,3-butadiene. Presumed to form
explosive peroxides.
Diethylether-Bortrifluorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-ETHOXY-7-HYDROXY-CHROMEN-2-ONE
2-Bromo-5-hydroxypyridine radical ion(1+)
2-Chloro-5-cyano-3-methylpyridine
(tert-Butoxymethyl)oxiran
1-(4-Morpholinobutyl)hydrazine
1-(3-Methyl-2-thienyl)ethan-1-on
2-MORPHOLINOISONICOTINALDEHYDE
1-Butoxy-2,3-epoxy-propan
2-FLUORO-5-HYDROXYBENZOIC ACID
2-Methyl-1,3-dithian
2-ACETYL-3-METHYLBENZO[B]THIOPHENE
4-Nitrophenyl-β-D-galaktopyranosid
(Bromomethyl)cyclobutane
2-Bromo-4-pyridinecarboxaldehyde
1-(3-(pyrrolidin-1-yl)propyl)hydrazine
2-CHLORO-5-IODO-3-METHYLPYRIDINE
2,5-DIMETHYL-1,3-OXAZOLE-4-CARBONYL CHLORIDE
Hydroxytyrosol
5-Bromo-7-azaindole
4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-on
1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4S)-(9CI)
2-(TRIFLUOROACETYL)THIOPHENE
Ethyl-N-(2-ethoxy-1,2-dihydrochinolin)carboxylat
1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4R)-(9CI)
1-Boc-Azetidine-3-yl-methanol
1-(4-(Pyrrolidin-1-yl)butyl)hydrazine
3-CYCLOPENTENE-1-OL
(Dihydro-3,3-diphenyl-3H-furan-2-yliden)dimethylammoniumbromid
(2-MORPHOLINOPYRID-4-YL)METHANOL
2-(2-NAPHTHYL)-1H-INDOLE-3-CARBALDEHYDE
4,5,6,7-TETRAHYDRO-2-METHYLFURO[2,3-C]PYRIDINE
4-Nitrophenyl-β-D-glucopyranosid
1,4-DIOXANE-2-CARBOXALDEHYDE
