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Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester Struktur
74936-72-4
CAS-Nr.
74936-72-4
Bezeichnung:
Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat
Englisch Name:
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
Synonyma:
PRAN-001;278-034-2;Le Chi Chi;1,4-DHPCOOH;Nicardipine USP RC A;Nifedipine Impurity 2;Le Chi mother nucleus;Lercanidipine nucleus;Lercanidipine mainring;Nimodipine Impurity 7
CBNumber:
CB62129651
Summenformel:
C16H16N2O6
Molgewicht:
332.31
MOL-Datei:
74936-72-4.mol
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Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Eigenschaften

Schmelzpunkt:
200-202?C
Siedepunkt:
505.0±50.0 °C(Predicted)
Dichte
1.345±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
Löslichkeit
DMSO (Sparingly), Methanol (Slightly, Heated)
Aggregatzustand
Solid
pka
1.66±0.70(Predicted)
Farbe
Pale Yellow to Light Yellow
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
HS Code  2934999090
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid(1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester) is a pharmaceutical intermediate ingredient used in the preparation of Barnidipine, Lercanidipine hydrochloride and nitrendipine analogues. These drugs are all calcium channel blockers and are used to treat various forms of hypertension.

Chemische Eigenschaften

Light-Yellow Solid

Verwenden

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester can be used in the prevention and therapy of atherosclerotic degradation of arterial walls.

Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Manidipine

Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 278)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED
+8618523575427
 sales@conier.com China 49391 58
Chongqing Ensky Pharmaceutical Co.,Ltd.
+86-23-86815286 +86-13983794297
 sales@ensky-chemical.com China 91 58
Xuchang Hengsheng Pharmaceutical Co., Ltd 		+86-03745692999 +86-13569491380
 xccxn@xchsyy.com China 15 58
Frapp's ChemicalNFTZ Co., Ltd. 		+86 (576) 8169-6106
sales@frappschem.com China 885 50
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806
 sales@capotchem.com China 29798 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497
sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21668 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714
 fandachem@gmail.com China 9332 55
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29892 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715
 admin@nexconn.com China 10312 58

74936-72-4(Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat)Verwandte Suche:

1-Benzylpiperidin-3-ol 1,4-Dihydro-2,6-dimethyl-4-(2-ni-trophenyl)-3,5-pyridindicarbon-säure-dimethylester Dimethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Nimodipin Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Niludipin 2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylatmonohydrochlorid 2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridin-3,5-dicarboxylat Nitrendipin
  • 2,6-DIMETHYL-5-METHOXY CARBONYL-4-(3-NITRO-PHENYL)-1,4-DIHYDROPYRIDINE-3-CARBOXYLIC ACID
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
  • Lercanidipine mainring
  • rac-1,4-Dihydro-5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic Acid
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl ester
  • 2,6-DiMethyl-5-Methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydorpyridine-3-carboxylic acid
  • Methyl hydrogen 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
  • 1,4-Dihydro-2,6-diMethyl-4-(3-nitrophenyl)-3,5-pyr
  • 1,4-DHPCOOH
  • 1,4-DIHYDRO-5-METHOXYCARBONYL-2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3-CARBOXYLIC AC
  • 2,6-DI-ME-4-(3-NITRO-PH)-1,4-2H-PYRIDINE-3,5-DICAR
  • Nicardipine Carboxylic Acid Derivative
  • Nifedipine Impurity 2
  • Le Chi mother nucleus
  • Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
  • Nifedipine Impurity 2 (Nicardipine Carboxylic Acid Derivative )
  • 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl ester
  • Lercanidipine nucleus
  • -1,4-dihydropyridine-3-carboxylic acid
  • -2,6-dimethyl-4-(3-nitrophenyl)
  • PHARMACEUTICAL RAW MATERIAL : 2,6-DIMETHYL-5-METHOXYCARBONYL-4-(3-NITROPHENYL)-1,4- DIHYDROPYRIDINE -3- CARBOXYLIC ACID
  • 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydroxypyridine-3-carboxylic acid
  • Nicardipine Carboxylic Acid Derivative (Nifedipine Impurity 2)
  • Nimodipine Impurity 7
  • Nicardipine USP RC A
  • Lercanidipine Impurity 9
  • Le Chi Chi
  • 278-034-2
  • 2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
  • Nicardipine USP Related Compound A
  • PRAN-001
  • Benidipine Impurity 18
  • Le Cardipine Main Ring Reference
  • 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitro phenyl)-1,4 dihydropyridine-3-carboxylic acid (74936-72-4)
  • Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate >
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitro
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
  • Benidipine Intermediate
  • Nicardipine Related Compound A (Nicardipine Carboxylic Acid Impurity)
  • 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)...
  • Nicardipine Impurity88
  • Nicardipine Carboxylic acid DerivativeQ: What is Nicardipine Carboxylic acid Derivative Q: What is the CAS Number of Nicardipine Carboxylic acid Derivative Q: What is the storage condition of Nicardipine Carboxylic acid Derivative Q: What are the applications of Nicardipine Carboxylic acid Derivative
  • Lercanidipin Impurity 10
  • 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylic acid monomethyl ester
  • Methyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylicaci
  • 2,6-Dimethyl-5-methoxy carbonyl-4-(3-nitrophenylo)-1,4-dihydropyridine-3-carboxylic acid
  • Monomethyl 1, 4-dihydro-2, 6-dimethyl-4 -(3-nitrophenyl) pyridine-3, 5-dicarboxylic acid
  • Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, ≥ 98.0%
  • (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid
  • Nicardipine EP Impurity 4
  • Beninidipine hydrochloride impurity E
  • 74936-72-4
  • Heterocycle-Pyridine series
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
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