Sodium (2-Sulfonatoethyl)methanethiosulfonate

Sodium (2-Sulfonatoethyl)methanethiosulfonate Struktur
184644-83-5
CAS-Nr.
184644-83-5
Englisch Name:
Sodium (2-Sulfonatoethyl)methanethiosulfonate
Synonyma:
MTSES (sodium);SODIUM (2-SULFONATOETHYL)METHANETHIOSULFONATE;MTSES (Sodium (2-Sulfonatoethyl)methanethiosulfonate)
CBNumber:
CB62131173
Summenformel:
C3H9NaO5S3
Molgewicht:
244.27
MOL-Datei:
184644-83-5.mol

Sodium (2-Sulfonatoethyl)methanethiosulfonate Eigenschaften

Schmelzpunkt:
200-203°C
storage temp. 
Refrigerator
Löslichkeit
DMSO (Slightly), Methanol (Very Slightly), Water (Slightly)
Aggregatzustand
Solid
Farbe
White to Off-White
Stabilität:
Moisture Sensitive: Desiccate

Sicherheit

Sodium (2-Sulfonatoethyl)methanethiosulfonate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Methanethiosulfonates (MTS) are sulfhydryl-reactive compounds that form mixed disulfide linkages and are commonly used to study cysteine residues on proteins. Sodium (2-sulfonatoethyl)methanethiosulfonate (MTSES) is a negatively-charged, membrane impermeant MTS. It is highly reactive with ionized thiolates but not with unionized thiols and, therefore, targets sulfhydryl groups accessible from the aqueous medium. MTSES is used to probe the structural and functional properties of native proteins, particularly those associated with membranes, including channels and transporters. In addition, charged MTS compounds like MTSES are combined with cysteine scanning mutagenesis to study non-cysteine residues.

Chemische Eigenschaften

White Solid

Verwenden

Reacts specifically and rapidly with thiols to form mixed disulfides, Sodium (2-Sulfonatoethyl)methanethiosulfonate can be used to probe the structures of the ACh receptor channel of the GABAA receptor channel and of lactose permease.

Sodium (2-Sulfonatoethyl)methanethiosulfonate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Sodium (2-Sulfonatoethyl)methanethiosulfonate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • SODIUM (2-SULFONATOETHYL)METHANETHIOSULFONATE
  • MTSES (Sodium (2-Sulfonatoethyl)methanethiosulfonate)
  • MTSES (sodium)
  • 184644-83-5
  • MTS & Sulfhydryl Active Reagents
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