Aurora Kinase Inhibitor II

331770-21-9

CAS-Nr.: 331770-21-9

Englisch Name:: Aurora Kinase Inhibitor II

Synonyma:: IUN-70219;Aurora kinase inhibitor-2;N-(4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenyl)benzamide;Benzamide, N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-;inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aurora kinase inhibitor 2,Aurora kinase inhibitor-2,Aurora-B,Inhibitor

CBNumber:: CB63136779

Summenformel:: C23H20N4O3

Molgewicht:: 400.43

MOL-Datei:: 331770-21-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 24

Aurora Kinase Inhibitor II Eigenschaften

Siedepunkt:: 518.6±50.0 °C(Predicted)

Dichte: 1.321±0.06 g/cm3(Predicted)

storage temp.: 4°C, protect from light

Löslichkeit: DMF:0.25(Max Conc. mg/mL);0.62(Max Conc. mM)
DMF:PBS(pH7.2) (1:2):0.33(Max Conc. mg/mL);0.82(Max Conc. mM)
DMSO:2.5(Max Conc. mg/mL);6.2(Max Conc. mM)

Aggregatzustand: A crystalline solid

pka: 13.01±0.70(Predicted)

Farbe: White to yellow

Sicherheit

Aurora Kinase Inhibitor II Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC₅₀ = 0.39 μM). In MCF-7 cells, it blocks proliferation with an IC₅₀ value of 1.25 μM.

Aurora Kinase Inhibitor II Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Aurora Kinase Inhibitor II Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 24)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4351	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8014	62
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MQ (shanghai) Pharmaceuticals Co., Ltd.	13761635123	1014988033@qq.com	China	4930	55
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
BOC Sciences	--	info@bocsci.com	USA	0	65

Aurora kinase inhibitor-2
IUN-70219
N-(4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenyl)benzamide
inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aurora kinase inhibitor 2,Aurora kinase inhibitor-2,Aurora-B,Inhibitor
Benzamide, N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-
331770-21-9