Sulbenicillin Chemische Eigenschaften,Einsatz,Produktion Methoden
Definition
ChEBI: A penicillin antibiotic having a 6beta-[phenyl(sulfo)acetamido] side-chain.
Antimicrobial activity
α-Sulfobenzylpenicillin, a semisynthetic penicillin supplied
as the disodium salt. Its antimicrobial spectrum and pharmacokinetic pharmacokinetic
behavior closely resemble those of carbenicillin.
Following intravenous administration of 4 g, the mean plasma
concentration at 1 h was approximately 160 mg/L, with a
plasma elimination half-life of around 70 min. It is largely
excreted in the urine, about 80% of the dose appearing in the
first 24 h, less than 5% as the penicilloic acid. It has been
noted that the penicilloic acid causes much stronger platelet
aggregation than its parent. It is of very limited availability.
Sulbenicillin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte