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1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Struktur
84477-87-2
CAS-Nr.
84477-87-2
Englisch Name:
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Synonyma:
H-7;H-72HCl;H-7 inhibitor;Protein kinase inhibitor H-7;1-(5-Isoquinolylsulfonyl)-2-methylpiperazine;1-(5-isoquinolinesulfonyl)-2-methylpiperazine;Isoquinoline-5-sulfonic 2-methyl-1-piperazide;5-(2-methylpiperazine-1-sulfonyl)isoquinoline;5-(2-methylpiperazin-1-yl)sulfonylisoquinoline;1-(5-isoquinolinylsulfonyl)-2-methyl-piperazin
CBNumber:
CB6719627
Summenformel:
C14H17N3O2S
Molgewicht:
291.37
MOL-Datei:
84477-87-2.mol
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1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Eigenschaften

Siedepunkt:
495.3±55.0 °C(Predicted)
Dichte
1.277±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
Löslichkeit
ethanol: 20 mg/mL
Aggregatzustand
Solid
pka
7.69±0.40(Predicted)
Farbe
White to light yellow
BRN 
5482740

Sicherheit

WGK Germany  3
RTECS-Nr. TL9305000
F  10
Toxizität LD50 intravenous in mouse: 94mg/kg

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Definition

ChEBI: A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Biologische Aktivität

Protein kinase inhibitor. IC 50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ M respectively.

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 45)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32760 60
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15848 69
Shanghaizehan biopharma technology co., Ltd. 021-61350663 13052117465
 sales@zehanbiopharma.com China 1000 55
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
 2853530910@QQ.com China 8010 62
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136
 info@SuperLan-chem.com China 9887 58
DC Chemicals 021-58447131 13564518121
 sales@dcchemicals.com China 9412 58
InvivoChem 13549236410
 sales@invivochem.cn China 6749 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939
 shenlinxing@macklin.cn China 29803 58
  • 1-(5-isoquinolinesulfonyl)-2-methylpiperazine
  • 1-(5-isoquinolinylsulfonyl)-2-methyl-piperazin
  • 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
  • 1-(5-isoquinolinylsulfonyl)-2-*methylpiperazine F
  • 1-(5-ISOQUINOLINYLSULFONYL)-2-*METHYLPIP ERAZINE FRE
  • H-72HCl
  • 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, Isoquinoline-5-sulfonic 2-methyl-1-piperazide
  • (Isoquinoline-5-yl)(2-methylpiperazine-1-yl) sulfone
  • 1-(5-Isoquinolylsulfonyl)-2-methylpiperazine
  • 5-(2-methylpiperazin-1-yl)sulfonylisoquinoline
  • Isoquinoline-5-sulfonic 2-methyl-1-piperazide
  • 5-[(2-methyl-1-piperazinyl)sulfonyl]Isoquinoline
  • 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
  • H-7
  • Isoquinoline, 5-[(2-methyl-1-piperazinyl)sulfonyl]-
  • Protein kinase inhibitor H-7
  • H-7 inhibitor
  • 84477-87-2
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Kinase/Phosphatase Biology
  • Protein kinase A and protein kinase C (PKA and PKC)
  • Serine/Threonine Kinase Inhibitors
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