Trimethylphosphonoacetat
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- CAS-Nr.
- 5927-18-4
- Bezeichnung:
- Trimethylphosphonoacetat
- Englisch Name:
- Trimethyl phosphonoacetate
- Synonyma:
- TMPA;METHYL DIMETHYLPHOSPHONOACETATE;Methyl (dimethoxyphosphoryl)acetate;NSC 84262;TriMethyl phosphonoacetat;TRIMETHYL PHOPHONOACETATE;trimethylacetyl phosphate;Trimethylphosphoroacetate;TRIMETHYL PHOSPHONACETATE;RIMETHYL PHOSPHONOACETATE
- CBNumber:
- CB6726270
- Summenformel:
- C5H11O5P
- Molgewicht:
- 182.11
- MOL-Datei:
- 5927-18-4.mol
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Trimethylphosphonoacetat Eigenschaften
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| S-Sätze: |
23-24/25 |
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| WGK Germany |
3 |
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| F |
9 |
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| TSCA |
Yes |
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| HS Code |
29310095 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H227 |
Combustible liquid |
Flammable liquids |
Category 4 |
Warnung |
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P210, P280, P370+P378, P403+P235,P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
| P405 |
Unter Verschluss aufbewahren. |
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Trimethylphosphonoacetat Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
clear colorless to light yellow liquid
Verwenden
Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.
Application
Trimethyl phosphonoacetate is an important Wittig-horner reagent, which can be used to manufacture important intermediates of natural compounds such as vitamins, drugs, insect pheromones, etc.
Reactant involved in:
Intramolecular Mannich-type reactions to produce the sarain A diazatricyclic core
Organocatalytic oxa-Michael reactions
Prenylation and geranylation of oxindoles
Intramolecular Horner-Wadsworth-Emmons reactions
Olefin cross-metathesis / heterocyclization
Trimethylphosphonoacetat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Trimethylphosphonoacetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 383)Lieferanten
5927-18-4(Trimethylphosphonoacetat)Verwandte Suche:
- TriMethyl phosphonoacetate, 98% 25GR
- Dimethylphosphonoacetic Acid Methyl Ester
Methyl Dimethylphosphonoacetate
Phosphonoacetic Acid Trimethyl Ester
- TriMethyl phosphonoacetat
- Aceticacid, 2-(diMethoxyphosphinyl)-, Methyl ester
- Dibenzyloxyphosphoiyl three Methyl acetate
- (Carboxymethyl)phosphonic acid trimethyl ester
- Dimethyl methoxycarbonylmethylphosphonate~Phosphonoacetic acid trimethyl ester
- trimethylacetyl phosphate
- TRIMETHYL PHOPHONOACETATE
- Dimethyl (methoxycarbonyl)methylphosphonate, 98 %
- (Dimethoxyphosphinyl)acetic acid methyl
- 2-(Dimethoxyphosphinyl)acetic acid methyl
- Dimethoxyphosphinylacetic acid methyl
- Methoxycarbonylmethylphosphonic acid dimethyl ester
- (Dimethoxy-phosphoryl)-aceticacidmethylester
- Trimethylphosphonoacetate,98%
- TriMethyl phosphonoacetate, 98% 100GR
- NSC 84262
- Dimethyl methoxycarbonylmethanephosphonate for synthesis
- (dimethoxyphosphinyl)-aceticacimethylester
- Trimethylphosphoroacetate
- (DIMETHOXYPHOSPHINYL)ACETIC ACID METHYL ESTER
- DIMETHYL METHOXYCARBONYLMETHANEPHOSPHONATE
- DIMETHYL (METHOXYCARBONYL)METHYLPHOSPHONATE
- DIMETHYLPHOSPHONOACETIC ACID METHYL ESTER
- ACETIC ACID, (DIMETHOXYPHOSPHINYL)-, METHYL ESTER
- PHOSPHONOACETIC ACID TRIMETHYL ESTER
- TRIMETHYL PHOSPHONACETATE
- TRIMETHYL PHOSPHONOACETATE
- Trimethylphosphonoyl acetate
- TrimethylPhosphonoacetate>
- Trimethyl phosphonoacetate, 98%, for synthesis
- Trimethyl phosphonylacetate
- RIMETHYL PHOSPHONOACETATE
- TMPA
- METHYL DIMETHYLPHOSPHONOACETATE
- Methyl (dimethoxyphosphoryl)acetate
- Phosphonyl acetate trimethyl ester
- 5927-18-4
- CH3O2POCH2CO2CH3
- C5H11O5P
- Horner-Wadsworth-Emmons Reagents
- Olefination
- Synthetic Reagents
- Wittig & Horner-Emmons Reaction
- Horner-Emmons Reaction
- C-C Bond Formation
- Horner-Emmons Reaction
- Synthetic Organic Chemistry
- Wittig & Horner-Emmons Reaction
- C-C Bond Formation
- Horner-Wadsworth-Emmons Reagents
- Olefination
- 5927-18-4
