dBRD9

2170679-45-3

CAS-Nr.: 2170679-45-3

Englisch Name:: dBRD9

Synonyma:: dBRD9;DBRD09;dBRD-9|||dBRD 9;2-((2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)(methyl)amino)-N-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)acetamide;Acetamide, 2-[[[4-(1,2-dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2,6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-

CBNumber:: CB74667813

Summenformel:: C40H45N7O10

Molgewicht:: 783.84

MOL-Datei:: 2170679-45-3.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 32

dBRD9 Eigenschaften

Siedepunkt:: 1014.2±65.0 °C(Predicted)

Dichte: 1.357±0.06 g/cm3(Predicted)

pka: 10.74±0.40(Predicted)

Aggregatzustand: Solid

Farbe: Light yellow to yellow

InChIKey: AIOCFZJGGGEWDK-UHFFFAOYSA-N

SMILES: O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC(NCCOCCOCCNC(=O)CN(C)CC3C(=CC(C4=CN(C)C(=O)C5=CN=CC=C45)=CC=3OC)OC)=C12

Sicherheit

dBRD9 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

dBRD9 is a potent and selective Degrader (PROTAC?) of BRD9 (IC50 = 56.6 nM in MOLM-13 cells). dBRD9 is composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide. Does not degrade BRD4 or BRD7 at concentrations up to 5 μM. Displays antiproliferative effects in human AML cell lines.

dBRD9 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

dBRD9 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 32)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hubei Chuchang Biotech Co., Ltd.	+undefined15623860702	info@chuchangbiotech.com	China	111	58
Shanghai finete Pharmaceutical Co., Ltd.	+86-18221039705		CHINA	139	55
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4822	58
Changzhou Borl Biotechnology Co.,LTD	13606124132;13656121842	luyan0021@163.com	China	216	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4287	55
ShangHai Angti Biotechnology Co., Ltd.	13764913901	info@angtibio.com	China	4923	55
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2972	58

dBRD9
2-((2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)(methyl)amino)-N-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)acetamide
Acetamide, 2-[[[4-(1,2-dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2,6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-
DBRD09
dBRD-9|||dBRD 9
2170679-45-3