4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitrile

143782-28-9

CAS-Nr.: 143782-28-9

Englisch Name:: 4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitrile

Synonyma:: 4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitril;4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitrile;Benzonitrile, 4-(4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-(trifluoromethyl)-

CBNumber:: CB75478496

Summenformel:: C13H10F3N3OS

Molgewicht:: 313.3

MOL-Datei:: 143782-28-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 1

4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitrile Eigenschaften

Siedepunkt:: 407.3±55.0 °C(Predicted)

Dichte: 1.48±0.1 g/cm3(Predicted)

pka: 10.40±0.40(Predicted)

Sicherheit

4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitrile Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitrile is used in the preparation of MDV 3100 (Enzalutamide)(M199800) which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.

4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitrile Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitrile Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 1)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
CLEARSYNTH LABS LTD.	--	sales@clearsynth.com	India	6351	58

4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitrile
4-(4,4-Dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-trifluoromethylbenzonitril
Benzonitrile, 4-(4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-(trifluoromethyl)-
143782-28-9