Duloxetine hydrochloride
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- CAS-Nr.
- 136434-34-9
- Englisch Name:
- Duloxetine hydrochloride
- Synonyma:
- DULOXETINE HCL;Duloxetime;DuL;CS-488;LY-248686;LY-248686 HCl;S-Duloxetine HCl;oxetine HydrochL;(RS)Duloxetine HCl;Duloxetine Pellets
- CBNumber:
- CB7724192
- Summenformel:
- C18H20ClNOS
- Molgewicht:
- 333.88
- MOL-Datei:
- 136434-34-9.mol
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Duloxetine hydrochloride Eigenschaften
- Schmelzpunkt:
- 118-122°C
- Flammpunkt:
- 9℃
- storage temp.
- room temp
- Löslichkeit
- H2O: soluble5mg/mL (clear solution, warmed)
- pka
- pKa in DMF-water (66:34): 9.6(at 25℃)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Optische Aktivität
- [α]/D +116 to +125°, c = 1 in methanol
- Merck
- 14,3465
- InChI
- InChI=1/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/s3
- InChIKey
- BFFSMCNJSOPUAY-VOPAOICTNA-N
- SMILES
- C1(=CC=CS1)[C@H](CCNC)OC1=CC=CC2=CC=CC=C12.Cl |&1:5,r|
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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Sicherheit |
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Duloxetine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
White Crystalline Solid
Verwenden
Duloxetine Hydrochloride acts as an antidepressant and a dual serotonin and norepinephrine reuptake inhibitor (SNRI) (1,2). Exhibits linear pharmacokinetics in mice and is not associated in any drastic changes of blood pressure or heart rate (3).
Definition
ChEBI: A duloxetine hydrochloride in which the duloxetine moiety has S configuration.
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Duloxetine hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Duloxetine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 714)Lieferanten
136434-34-9()Verwandte Suche:
- LY-248686 HCl
- (γS)-N-methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride (1:1)
- (+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride
- LY-248686 hydrochloride
- Duloxetine for system suitability
- Duloxetine hydrochloride solution
- (S)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine hydrochloride
- Methanol( Test Duloxetine HCl, 1.0 mg/mL as free base)
- (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride
- N-Methyl-gaMa-(1-naphthalenyloxy)-2-thiophenepropa
- (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylaMine Hydrochloride
- (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanaMine Hydrochloride
- S-Duloxetine HCl
- N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride
- (S)-N,N-DiMethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride
- (S)-Duloxetine hydrochloride(CyMbalta)
- LY-248686
- DULOXETINE HYDROCHLORIDE
- N-methyl-gamma-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride
- (+)-(S)-N-Methyl-g-(1-naphthyloxy)-2-thiophenepropylamine
- (gS)-N-Methyl-g-(1-naphthalenyloxy)-2-thiophenepropanamine
- (+)-(S)-N-Methyl-g-(1-naphthyloxy-d7)-2-thiophenepropylamine
- (gS)-N-Methyl-g-(1-naphthalenyloxy-d7)-2-thiophenepropanamine
- DULOXETINE: DULOXETINE HYDROCHLORIDE
- N-Methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine
- (+)-(S)-N-Methyl--(1-naphthyloxy)-2-thiophenepropylamine
- (S)-N-Methyl--(1-naphthalenyloxy)-2-thiophenepropanamine
- (+)-(S)-N-Methyl--(1-naphthyloxy-d7)-2-thiophenepropylamine
- (S)-N-Methyl--(1-naphthalenyloxy-d7)-2-thiophenepropanamine
- (RS)Duloxetine HCl
- (RS)-DULOXEINEHYDROCHLORIDE
- Duloxetine HCl and intermediates
- (+)-(S)-n-methyl-g-(1-naphthyloxy)-2-thiophenepropylamine, hydrochloride/duloxetinehcl
- Duloxetine hydrochloride ,99%
- (S)-DULOXETINE HYDROCHLORIDE
- (+)-(S)-N-METHYL-3-(1-NAPHTHYLOXY)--3-(2-THIENYL)PROPANAMINE HYDROCHLORIDE
- (S)-N-METHYL-3-(NAPHTHALEN-1-YLOXY)-3-(THIOPHEN-2-YL)PROPAN-1-AMINE HCL
- (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride
- CS-488
- Duloxetine hydrochloride, ≥98.0%(HPLC)
- (S)-DULOXETINE HYDROCHLORIDE;LY-248686 HYDROCHLORIDE
- Duloxetine hydrochloride CRS
- DuloxetineHydrochloride>
- Duloxetine hydrochloridum
- Duloxetine for system suitability CRS
- oxetine HydrochL
- (S)-(+)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine Hydrochloride
- Duloxetine hydrochloride USP/EP/BP
- Duloxetine Hydrochloride (1.0 mg/mL in Methanol)
- methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-
yl)propyl]amine hydrochloride
- (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine
- Duloxetine HCl (LY-248686 HCl)
- Duloxetine HydrochlorideQ: What is
Duloxetine Hydrochloride Q: What is the CAS Number of
Duloxetine Hydrochloride Q: What are the applications of
Duloxetine Hydrochloride
- Duloxetine for system suitability (Y0001454)
- Duloxetine hydrochloride (Y0001453)
- Duloxetine Hydrochloride (1229817)
- Duloxetime
- DULOXETINE HCL