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3-O-Methylquercetin

3-O-Methylquercetin Struktur
1486-70-0
CAS-Nr.
1486-70-0
Englisch Name:
3-O-Methylquercetin
Synonyma:
NSC 154016;3-Methylquercetol;3-Methoxyluteolin;Rutoside Trihydrate Impurity 8;3',4',5,7-Tetrahydroxy-3-methoxyflavone;TETRAHYDROXY-3-METHOXYFLAVONE, 3',4',5,7-(RG);2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-chroMen-4-one;2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-1-benzopyran-4-one;2-(3,4-Dihydroxyphenyl)-3-methoxy-5,7-dihydroxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-
CBNumber:
CB81075557
Summenformel:
C16H12O7
Molgewicht:
316.26
MOL-Datei:
1486-70-0.mol
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3-O-Methylquercetin Eigenschaften

Schmelzpunkt:
275 °C
Siedepunkt:
643.0±55.0 °C(Predicted)
Dichte
1.69±0.1 g/cm3(Predicted)
Löslichkeit
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Aggregatzustand
powder
pka
6.31±0.40(Predicted)
Farbe
Yellow
BRN 
324509
Stabilität:
Hygroscopic
LogP
2.020 (est)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher T
R-Sätze: 25
S-Sätze: 45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizität oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

3-O-Methylquercetin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.
3-O-Methylquercetin significantly inhibits cyclic adenosine monophosphate- (cAMP-) and cyclic guanosine monophosphate- (cGMP-) phosphodiesterase activity. It possess anti-inflammatory, bronchodilating properties and used in treatment of asthma. It suppresses the total inflammatory cells, tumor necrosis factor-α (TNF-α) and attenuates the production of interleukins.

Verwenden

A metabolite of the flavanoid Quercetin (Q509500) with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells.

Definition

ChEBI: A tetrahydroxyflavone having the 4-hydroxy groups located at the 3'- 4'- 5- and 7-positions as well as a methoxy group at the 2-position.

Biologische Aktivität

3-O-Methylquercetin isolated from the herbs of Croton cascarilloides. It is a selective and competitive PDE3/PDE4 inhibitor,and inhibits PDE3 than PDE4 with a low K(m) value; it inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.

3-O-Methylquercetin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4-benzopyron QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER 4',7-DIMETHOXY-3,3',5-TRIHYDROXYFLAVONE AYANIN 3,3',4',5-Tetrahydroxy-7-methoxyflavon Quercetin Methyljodid

Downstream Produkte

3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE

3-O-Methylquercetin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 107)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chengdu Biopurify Phytochemicals Ltd. 		+8618080483897
 sales@biopurify.com China 3772 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254
linda@hubeijusheng.com CHINA 28172 58
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63687 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29811 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626
 eric@witopchemical.com China 23541 58
Henan Alfa Chemical Co., Ltd
China 10947 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152
 Mandy@hangyubiotech.com China 10986 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501
 product@acmec-e.com China 33338 58

1486-70-0()Verwandte Suche:

3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyron 2-(3,4-Dihydroxyphenyl)-3-(β-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-on 3-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-on Quercitrin 2-(3,4-Dihydroxyphenyl)-3-(β-D-galaktopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-on 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4-benzopyron Rutosid 3-[(6-Desoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-benzopyran-4-on 3,3',4',5-Tetrahydroxy-7-methoxyflavon 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyron 2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-3,5-dihydroxy-6-methoxy-4H-1-benzopyran-4-on
  • 3',4',5,7-Tetrahydroxy-3-methoxyflavone
  • 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-1-benzopyran-4-one
  • 3-Methylquercetol
  • NSC 154016
  • 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-chroMen-4-one
  • 2-(3,4-Dihydroxyphenyl)-3-methoxy-5,7-dihydroxy-4H-1-benzopyran-4-one
  • TETRAHYDROXY-3-METHOXYFLAVONE, 3',4',5,7-(RG)
  • 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-
  • Rutoside Trihydrate Impurity 8
  • 3-Methoxyluteolin
  • 3OMethylquercetin,Phosphodiesterase (PDE),inhibit,3 O Methylquercetin,Inhibitor
  • 1486-70-0
  • Penta-substituted Flavones
  • Miscellaneous Natural Products
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
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