Pramipexole Impurity 16
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- CAS-Nr.
- 104632-27-1
- Englisch Name:
- Pramipexole Impurity 16
- Synonyma:
- RPPX;Kns 760704;Snd 919cl2x;Dexpramipexole HCl;Dexpramipexole 2HCl;Pramipexole R-Isomer;PraMipexole IMpurity D;Pramipexole BP Impurity D;Pramipexole impurity D CRS;KNS-760704 dihydrochloride
- CBNumber:
- CB82449027
- Summenformel:
- C10H18ClN3S
- Molgewicht:
- 247.79
- MOL-Datei:
- 104632-27-1.mol
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Pramipexole Impurity 16 Eigenschaften
- storage temp.
- -20°C
- Löslichkeit
- H2O: >15mg/mL
- Aggregatzustand
- powder
- Farbe
- white to beige
- Optische Aktivität
- [α]/D 60 to 70°, c = 1 in methanol
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xi |
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| R-Sätze: |
36/37/38 |
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| S-Sätze: |
26 |
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| WGK Germany |
3 |
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| HS Code |
2934200000 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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Pramipexole Impurity 16 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Pramipexole (Item No.
11981) is an agonist of dopamine receptors that has applications in Parkinson’s disease and other disorders. Pramipexole is usually available as a mixture of enantiomers, with the majority of the dopamine receptor-dependent activity resulting from the (S) form. (R)-Pramipexole is an enantiomer of pramipexole that is ~100-fold less active than the (S) form as a dopamine receptor agonist. For this reason, it can be used as a negative control for the (S) form in the study of dopamine receptors. Both isoforms are antioxidants that target mitochondria to prevent apoptosis. This cytoprotective effect of (R)-pramipexole, without dopaminergic side effects, suggests utility in amyotrophic lateral sclerosis.
Verwenden
(R)-Pramipexole Dihydrochloride (Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D) is the opposite enantiomer of Pramipexole (P700755), a dopamine-D2-receptor agonist. Dexpramipexole is a low-molecular-weight, water-soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics.
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pramipexole Related Compound D is a pharmaceutical impurity of pramipexole. Pramipexole is a non-ergot dopamine receptor agonist, widely used in the treatment of Parkinson′s disease.
Pramipexole Impurity 16 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Pramipexole Impurity 16 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 83)Lieferanten
104632-27-1()Verwandte Suche:
- 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, (R)-
- Kns 760704
- Snd 919cl2x
- DexpraMipexole (dihydrochloride)
- PraMipexole IMpurity D
- (R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride // (R)-Pramipexole dihydrochloride
- (R)-4,5,6,7-Tetrahydro-6-(propylamino)-benzothiazole-2-amine dihydrochloride
- RPPX
- Pramipexole Dihydrochloride Hydrate Impurity
- (R)-Pramipexole (hydrochloride)
- Pramipexole Dihydrochloride Hydrate IMP
- Pramipexole dihydrochloride impurity IV
- (R)-PRAMIPEXOLE DIHYDROCHLORIDE; KNS 760704; SND 919CL2X
- Pramipexole R-Isomer
- Pramipexole EP Impurity D DiHCl
- (6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine,dihydrochloride
- Dexpramipexole dihydrochloride
((R)-Pramipexole
- Pramipexole impurity D CRS
- KNS-760704 dihydrochloride
- (R)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine dihydrochloride
- Dexpramipexole HCl
- Pramipexole EP Impurity D ((R)-Pramipexole diHCl)
- Pramipexole Related Compound D ((R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydro (1553815)
- Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride
- Dopamine Receptor,inhibit,Inhibitor,KNS-760704,Dexpramipexole,Dexpramipexole dihydrochloride,(R)-Pramipexole,KNS760704,KNS 760704
- Pramipexole Impurity 4 Dihydrochloride（Pramipexole EP Impurity D Dihydrochloride）
- Dexpramipexole 2HCl
- Pramipexole EP Impurity D HCl
- Pramipexole Impurity D (R-Isomer)
- Glycerol Impurity 41((R)-3-chloropropane-1,2-diol)
- Pramipexole BP Impurity D
- 104632-27-1
- 28425
