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GeMigliptin

GeMigliptin Struktur
911637-19-9
CAS-Nr.
911637-19-9
Englisch Name:
GeMigliptin
Synonyma:
LC15-0444;GeMigliptin;GeMigliptin WS;Gemigliptin - G10587;GeMigliptin Tartarate;Gemigliptin Hydrochloride;Product name:-Gemigliptintartarate;Inhibitor,DPP,Gemigliptin,Dipeptidyl Peptidase,inhibit;(S)-1-(2-Amino-4-(2,4-bis(trifluoromethyl)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one;1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one
CBNumber:
CB82627898
Summenformel:
C18H19F8N5O2
Molgewicht:
489.36
MOL-Datei:
911637-19-9.mol
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GeMigliptin Eigenschaften

Siedepunkt:
539.1±50.0 °C(Predicted)
Dichte
1.54±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
DMSO:74.0(Max Conc. mg/mL);151.21(Max Conc. mM)
Ethanol:7.0(Max Conc. mg/mL);14.3(Max Conc. mM)
Water:12.0(Max Conc. mg/mL);24.52(Max Conc. mM)
Aggregatzustand
Solid
pka
7.33±0.10(Predicted)
Farbe
White to orange

Sicherheit

GeMigliptin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Gemigliptin is a prolyl-specific dipeptidyl aminopeptidase IV (DPP IV, DPP-4, CD26) inhibitor approved for the treatment of type 2 diabetes mellitus by the Korean Food and Drug Administration in 2012. Gemigliptin was discovered and developed by LG Life Sciences and is now the sixth DPP-4 inhibitor approved for the treatment of type 2 diabetes. At the time this review was prepared, there were no publications describing the discovery strategy and preclinical data that led to the advancement of gemigliptin to the clinic.

Verwenden

Gemigliptin Hydrochloride is used in biological studies as a novel dipeptidyl peptidase IV (DPP-IV) inhibitors and potential antidiabetic drug.

GeMigliptin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

GeMigliptin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 51)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21675 55
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838
chloewu@chicopharm.cn CHINA 341 58
Senova Technology Co. Ltd. 		+86-0755-86703119 +8618503098836
 info@senovatech.com China 350 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418684 +8618949823763
 sales@tnjchem.com China 25363 58
TargetMol Chemicals Inc. 		+1-781-999-5354
support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
Aceschem Inc. 		+1-817863-6948 +1-（817）863-6948
 sales@aceschem.com United States 19639 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8474 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43348 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501
 product@acmec-e.com China 33350 58
  • GeMigliptin
  • GeMigliptin Tartarate
  • Gemigliptin - G10587
  • (S)-1-(2-Amino-4-(2,4-bis(trifluoromethyl)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one
  • GeMigliptin WS
  • (S)-1-(2-amino-4-(2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one hydrochloride
  • LC15-0444
  • Gemigliptin Hydrochloride
  • Product name:-Gemigliptintartarate
  • 2-Piperidinone, 1-[(2S)-2-amino-4-[5,8-dihydro-2,4-bis(trifluoromethyl)pyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl]-5,5-difluoro-
  • 1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one
  • Inhibitor,DPP,Gemigliptin,Dipeptidyl Peptidase,inhibit
  • 911637-19-9
  • C18H19F8N5O2
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