N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride

883976-12-3

CAS-Nr.: 883976-12-3

Englisch Name:: N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride

Synonyma:: M8-B;M8-B hydrochloride;M8-B hydrochloride >=98% (HPLC);M8 B Hydrochloride,M-8-B Hydrochloride,M8B Hydrochloride;N-(2-Aminoethyl)-N-(4-(benzyloxy)-3-methoxybenzyl)thiophene-2-carboxamide hydrochloride;N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride;2-Thiophenecarboxamide, N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, monohydrochloride

CBNumber:: CB82750701

Summenformel:: C22H25ClN2O3S

Molgewicht:: 432.9635

MOL-Datei:: 883976-12-3.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 42

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Eigenschaften

storage temp.: 2-8°C

Löslichkeit: H2O: soluble2mg/mL, clear (warmed)

Aggregatzustand: powder

Farbe: white to beige

Sicherheit

WGK Germany	3

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin , or menthol in vitro (IC₅₀s = 7.8, 26.9, and 64.3 nM, respectively). It displays no effect at other TRP channels. M8-B decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 KO mice.

Verwenden

M8 B Hydrochloride is a channel blocker of cold receptor TRPM8.

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 42)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
HangZhou YuHao Chemical Technology Co., Ltd.	0571-82693216	info@yuhaochemical.com	China	2031	58
Chengdu Kamel Pharmaceutical Co., Ltd	028-67136579 15828051124	sales@kamelpharm.com	China	1822	55
Pharmacodia (Beijing) Co.,Ltd	+86-400-851-9921	sales@pharmacodia.com	China	2317	55

M8-B hydrochloride
N-(2-Aminoethyl)-N-(4-(benzyloxy)-3-methoxybenzyl)thiophene-2-carboxamide hydrochloride
N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride
2-Thiophenecarboxamide, N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, monohydrochloride
M8-B
M8-B hydrochloride >=98% (HPLC)
M8 B Hydrochloride,M-8-B Hydrochloride,M8B Hydrochloride
883976-12-3