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2'-O-MOE-A(Bz)-3'-phosphoramidite

2'-O-MOE-A(Bz)-3'-phosphoramidite Struktur
251647-53-7
CAS-Nr.
251647-53-7
Englisch Name:
2'-O-MOE-A(Bz)-3'-phosphoramidite
Synonyma:
DMT-2'-O-MOE-A(Bz)-CE;2’-MOE-dA(Bz) Amidite;2’-MOE-dA(Bz) Amidite;N6-Bz-5'-O-DMT-2'-O-MOE-A-CE;2'-O-MOE-Bz-A Phosphoramidite;2'-MOE-N-Bz Adenosine Amidite;2'-MOE-Bz-A CE Phosphoramidite;2'-MOE-Bz-A CE Phosphoramidite;2'-O-MOE-rA(Bz)Phosphoramidite;2'-O-MOE-rA(Bz) Phosphoramidite)
CBNumber:
CB83051689
Summenformel:
C50H58N7O9P
Molgewicht:
932.01
MOL-Datei:
251647-53-7.mol
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2'-O-MOE-A(Bz)-3'-phosphoramidite Eigenschaften

pka
7.87±0.43(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white
InChIKey
VPBYBQBHLYRLHG-VCCSSPGHNA-N
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P330 Mund ausspülen.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

2'-O-MOE-A(Bz)-3'-phosphoramidite Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

2'-O-MOE-A(Bz)-3'-phosphoramidite, also known as DMT-2'-O-MOE-rA(Bz) phosphoramidite, inserts 2'-O-methoxyethyl-modified adenosine into oligonucleotide phosphoramidites for antisense RNA. Its 2'-MOE backbone bolsters duplex stability, nuclease resistance, and has low toxicity, contributing to effective, safe genetic manipulation. It is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

Chemische Eigenschaften

The IUPAC name of 2'-O-MOE-A(Bz)-3'-phosphoramidite is (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. It is white to off-white powder.

2'-O-MOE-A(Bz)-3'-phosphoramidite Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2'-O-MOE-A(Bz)-3'-phosphoramidite Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 115)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Zhejiang Hengkang Pharmaceutical Co., Ltd.
+86-576-83372028 +86-18868723926
 bd1@hengkangpharm.cn China 119 58
Allbiosyn Biotechnology Co.,Ltd.
+8618666985712
 info@allbiosyn.com China 255 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886
info@dakenam.com China 16208 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715
 admin@nexconn.com China 10318 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30253 58
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629
 sales@newcanbio.com China 9980 58
Wuhu Nuowei chemistry Co., Ltd. 		+86-0553-2911116-802 +undefined17756524438
 sales1@nuowei-chem.com China 1640 58
Chemtour Biotech Co., Ltd 		+8617327281506
 market@chemtour.com China 1460 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD 		+86-0512-83500002 +8615195660023
 sales@senfeida.com China 23053 58
  • 2'-O-MOE-A(Bz)-3'-phosphoramidite
  • N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
  • ADENOSINE, N-BENZOYL-5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI)
  • 2'-O-MOE-Bz-A Phosphoramidite
  • N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
  • 2'-O-MOE-A(Bz)-CE Phosphoramidite
  • 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-ME-A(BZ) PHOSPHORAMIDITE
  • DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite
  • N6-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite
  • Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
  • N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite
  • 2'-O-MOE-rA(Bz) Phosphoramidite)
  • 5'-O-DMT-N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
  • Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite
  • 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-N6-benzoyl-adenosine -3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 5'-DMTr-2'-MOE-N6-Bz-3'-CEP-Adenosine
  • 5'-DMTr-2'-MOE-N6Bz-3'-O-CEP-ADENOSINE
  • DMT-2′O-MOE-rA(bz) Phosphoramidite
  • 2’-O-MOE-A(Bz)-3’-phospho ramidite, N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite
  • N6-Bz-5’-O-DMTr-2’-O-(2-methoxyethyl)-adenosine-3’-CED-phosphoramidite
  • N6-Bz-5'-O-DMT-2'-O-MOE-A-CE
  • 5'-O-DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite
  • 2'-MOE-Bz-A CE Phosphoramidite
  • 5'-O-DMT-2'-O-MOE-N6-Benzoyl- Adenosine -3’-Cyanoethyl Phosphoramidite
  • 2'-MOE-N-Bz Adenosine Amidite
  • DMT-2'-O-MOE-A(Bz)-CE
  • DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite
  • 2’-MOE-dA(Bz) Amidite
  • N6-Benzoyl-2-o-methyladenosine 3-ce phosphoramidite
  • N6-Benzoyl-5’-O-(4, 4’-dimethoxytrityl)-2’-O-(2-methoxyethyl)adenosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 5'-ODMT-2'-OMOE-N-Bz Adenosine-3'-OCEPA
  • 2'-O-MOE-A(Bz)-3'-phosphoramidite
  • DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite
  • 2'-MOE-Bz-A CE Phosphoramidite
  • 2'-O-MOE-A(Bz)-CE-Phosphoramidite
  • 2’-MOE-dA(Bz) Amidite
  • N6-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite
  • (2R,3R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
  • N6-Bz-2'-O-MOE-5'-O-DMT-A-3'-CE-Phosphoramidite
  • 2'-O-MOE-rA(Bz)Phosphoramidite
  • 251647-53-7
  • C50H58N7O9P
  • Amidite
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