MI-136

1628316-74-4

CAS-Nr.: 1628316-74-4

Englisch Name:: MI-136

Synonyma:: MI-136;CS-2162;MI136;MI 136;HY-19319 (MI 136;MI-136;HY-19319 (MI 136; MI136);;5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in;5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile;1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-;PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen Receptor,Epigenetic Reader Domain,prostate

CBNumber:: CB83121119

Summenformel:: C23H21F3N6S

Molgewicht:: 470.51

MOL-Datei:: 1628316-74-4.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 65

MI-136 Eigenschaften

Siedepunkt:: 654.9±55.0 °C(Predicted)

Dichte: 1.45±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 10 mg/ml

Aggregatzustand: A crystalline solid

pka: 14.20±0.30(Predicted)

Farbe: White to off-white

Sicherheit

MI-136 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

MI-136 is an inhibitor of the menin-MLL interaction (IC₅₀ = 31 nM; K_d = 23.6 nM). By blocking MLL recruitment predominantly at the level of the menin-MLL interaction, it can inhibit androgen receptor (AR)-mediated transcription. At 40 mg/kg, MI-136 has been shown to block AR signaling, inhibiting the growth of castration-resistant tumors in mice.

MI-136 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

MI-136 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 65)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4694	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58

1628316-74-4()Verwandte Suche:

Ceftazidim

MI-136
MI-136;HY-19319 (MI 136; MI136);
HY-19319 (MI 136
1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-
5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile
5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in
MI136;MI 136
CS-2162
PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen Receptor,Epigenetic Reader Domain,prostate
1628316-74-4
C23H21F3N6S