Sacubitril Impurity 7
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- CAS-Nr.
- 149709-44-4
- Englisch Name:
- Sacubitril Impurity 7
- Synonyma:
- LBQ657;LCZ696-4;Sacubitrilat;Deethyl Sakuba;LCZ-696 Impurity 1;SACUBITRIL DI ACID;Diacid of Sacubitril;LCZ696 impurities124;LBQ-657(Sacubitrilat);Sacubitrilat (LBQ-657)
- CBNumber:
- CB83133439
- Summenformel:
- C22H25NO5
- Molgewicht:
- 383.44
- MOL-Datei:
- 149709-44-4.mol
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Sacubitril Impurity 7 Eigenschaften
- Siedepunkt:
- 705.4±60.0 °C(Predicted)
- Dichte
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Löslichkeit
- DMF:30.0(Max Conc. mg/mL);78.24(Max Conc. mM)
DMSO:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.3(Max Conc. mM)
- Aggregatzustand
- A crystalline solid
- pka
- 4.59±0.23(Predicted)
- Farbe
- White to off-white
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
Sacubitril Impurity 7 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
Sacubitril Impurity 7 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Sacubitril Impurity 7 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 106)Lieferanten
- LBQ657
- Sacubitrilat
- (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid
- LCZ696-4
- Diacid of Sacubitril
- LCZ-696 Impurity 1
- Sacubitrilat (LBQ-657)
- Sacubitril Desethyl Impurity
- LCZ696 Impurity 900-04
- Deethyl Sakuba
- Sacubitril metabolite LBQ 657
- [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, (αR,γS)-
- 4-[[(1S,3R)-1-[([1,1'-Biphenyl]-4-yl)methyl]-3-methyl-4-hydroxy-4-oxobutyl]amino]-4-oxobutanoic acid
- (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)- 2-methylpentanoic aci
- Diacid of Sacubitril/ Sacubitril Desethyl Impurity/ Sacubitrilat
- LCZ696 impurities124
- Sacubitril metabolite LBQ 657Q: What is
Sacubitril metabolite LBQ 657 Q: What is the CAS Number of
Sacubitril metabolite LBQ 657 Q: What is the storage condition of
Sacubitril metabolite LBQ 657 Q: What are the applications of
Sacubitril metabolite LBQ 657
- quinoline,6-bromo-7-chloro-
- SACUBITRIL DI ACID
- Salcubatra calcium impurity J
- LBQ-657(Sacubitrilat)
- LCZ696 impurity 900-04（LBQ657）
- Sacubitril Diacid Impurity
- (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid
- Valsartan Impurity D-1
- 149709-44-4
- 14709-44-4
