1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[(1-2-METHYLSULPHONYLAMINO)ETHYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE

168986-61-6

CAS-Nr.: 168986-61-6

Englisch Name:: 1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[(1-2-METHYLSULPHONYLAMINO)ETHYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE

Synonyma:: RS 67506;RS67506HCl;RS 67506 HYDROCHLORIDE;N-[2-[4-[3-(4-amino-5-chloro-2-methoxyphenyl)-3-oxopropyl]piperidin-1-yl]ethyl]methanesulfonamide;1-(4-Amino-5-chloro-2-methoxyphenyl)-3-(1-2-methylsulfonylamino)ethyl-4-piperidinyl)-1-propanonehydrochloride;N-(2-(4-(3-(4-Amino-5-chloro-2-methoxyphenyl)-3-oxopropyl)piperidin-1-yl)ethyl)methanesulfonamide hydrochloride;1-(4-Amino-5-chloro-2-methoxyphenyl)-3-[1-2-methylsulphonylamino)ethyl-4-piperidinyl]-1-propanone hydrochloride;1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[(1-2-METHYLSULPHONYLAMINO)ETHYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE

CBNumber:: CB8335375

Summenformel:: C18H29Cl2N3O4S

Molgewicht:: 454.41

MOL-Datei:: 168986-61-6.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 16

1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[(1-2-METHYLSULPHONYLAMINO)ETHYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE Eigenschaften

storage temp.: Store at RT

Löslichkeit: Soluble to 80 mM in H2O

Aggregatzustand: Powder

Wasserlöslichkeit: Soluble to 80 mM in water

Sicherheit

1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[(1-2-METHYLSULPHONYLAMINO)ETHYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

RS 67506 Hydrochloride is a novel and potent 5-HT4 receptor agonist.

Definition

ChEBI: A hydrochloride salt obtained by mixing equimolar amounts of RS 39604 with hydrochloric acid. A potent and selective 5-HT4 antagonist, with a pKi of 9.1 at 5-HT4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT1A, 2C, 3 and D1, D2, M1, M2, AT1, B1 and alpha1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivo studies.

Biologische Aktivität

A potent and selective 5-HT 4 partial agonist, with a pK i of 8.8 at 5-HT 4 sites in guinea pig striatum, but < 6.0 at several other receptors including 5-HT 1A, 1D, 2A, 2C , D 1 , D 2 and M 1-3 . It is active in vivo and has an intrinsic activity compared to 5-HT of 0.6.

1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[(1-2-METHYLSULPHONYLAMINO)ETHYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[(1-2-METHYLSULPHONYLAMINO)ETHYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 16)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai YuZn Pharm. Technology Co.,Ltd.	15921286451; 15921286451	2010681527@qq.com	China	5064	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4659	58
ApexBio Technology	--	sales@apexbt.com	United States	6254	58

RS 67506 HYDROCHLORIDE
1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[(1-2-METHYLSULPHONYLAMINO)ETHYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE
1-(4-Amino-5-chloro-2-methoxyphenyl)-3-(1-2-methylsulfonylamino)ethyl-4-piperidinyl)-1-propanonehydrochloride
RS67506HCl
RS 67506
1-(4-Amino-5-chloro-2-methoxyphenyl)-3-[1-2-methylsulphonylamino)ethyl-4-piperidinyl]-1-propanone hydrochloride
N-[2-[4-[3-(4-amino-5-chloro-2-methoxyphenyl)-3-oxopropyl]piperidin-1-yl]ethyl]methanesulfonamide
N-(2-(4-(3-(4-Amino-5-chloro-2-methoxyphenyl)-3-oxopropyl)piperidin-1-yl)ethyl)methanesulfonamide hydrochloride
168986-61-6
C18H28ClN3O4SHCl
C18H29Cl2N3O4S