SR 12813

126411-39-0

CAS-Nr.: 126411-39-0

Englisch Name:: SR 12813

Synonyma:: GW485801;GW 485801;GW-485801;SR12813;SR 12813;SR-12813(GW 485801);SR-12813;SR12813;SR 12813;GW 485801;GW-485801;GW485801;GW-485801,GW485801,HMG-CoA Reductase (HMGCR),Autophagy,SR12813,inhibit,Inhibitor;Tetraethyl (2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethene-1,1-diyl)bis(phosphonate);[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonicacidtetraethylester;Phosphonic acid, P,P'-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-, P,P,P',P'-tetraethyl ester

CBNumber:: CB8497376

Summenformel:: C24H42O7P2

Molgewicht:: 504.53

MOL-Datei:: 126411-39-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 59

SR 12813 Eigenschaften

Schmelzpunkt:: 119-121℃

Siedepunkt:: 552.6±50.0 °C(Predicted)

Dichte: 1.117±0.06 g/cm3(Predicted)

storage temp.: Sealed in dry,Room Temperature

Löslichkeit: DMSO: ≥10 mg/mL

Aggregatzustand: solid

pka: 9.95±0.70(Predicted)

Farbe: White to off-white

Sicherheit

WGK Germany	3
HS Code	29319090

SR 12813 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

SR 12813 is a pregnane X receptor (PXR, NR 112) agonist.

Definition

ChEBI: An organic phosphonate that is the tetraethyl ester of [2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethene-1,1-diyl]bis(phosphonic acid).

Biologische Aktivität

Pregnane X receptor (PXR) agonist (EC 50 values are 200 and 700 nM for human and rabbit PXR respectively). Activates the farnesoid X receptor (FXR) at μ M concentrations. Displays hypocholesterolaemic activity via enchanced degradation of HMG-CoA reductase.

SR 12813 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SR 12813 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 59)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38632	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14055	65
Dalian Meilun Biotech Co., Ltd.	0411-62910999 13889544652	meilunui@163.com	China	4727	58
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4428	55

126411-39-0()Verwandte Suche:

Tetraethylmethylenbisphosphonat Dimethylvinylphosphonat Medroninsure Diethylvinylphosphonat

[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonicacidtetraethylester
SR-12813(GW 485801)
SR-12813;SR12813;SR 12813;GW 485801;GW-485801;GW485801
GW 485801
GW485801
GW-485801
SR12813;SR 12813
Phosphonic acid, P,P'-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-, P,P,P',P'-tetraethyl ester
GW-485801,GW485801,HMG-CoA Reductase (HMGCR),Autophagy,SR12813,inhibit,Inhibitor
Tetraethyl (2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethene-1,1-diyl)bis(phosphonate)
126411-39-0
C24H42O7P2