REVERSIN 121

174630-04-7

CAS-Nr.: 174630-04-7

Englisch Name:: REVERSIN 121

Synonyma:: REVERSIN 121;BOC-ASP(OBZL)-LYS(Z)-OTBU;L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester

CBNumber:: CB8699257

Summenformel:: C34H47N3O9

Molgewicht:: 641.75

MOL-Datei:: Mol file

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 32

REVERSIN 121 Eigenschaften

Siedepunkt:: 786.8±60.0 °C(Predicted)

Dichte: 1.163±0.06 g/cm3(Predicted)

storage temp.: −20°C

Löslichkeit: DMSO or ethanol: soluble

Aggregatzustand: powder

pka: 10.75±0.46(Predicted)

Farbe: white

Sicherheit

WGK Germany	3

REVERSIN 121 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a K_d value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma membrane vesicles from multidrug-resistant cells, and reconstituted proteoliposomes as well as in a variety of MDR1-expressing intact tumor cells.

Verwenden

Reversin 121 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.

Allgemeine Beschreibung

Reversin 121 is an analog of reversin and a dipeptide derivative.

REVERSIN 121 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

REVERSIN 121 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 32)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9708	58
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919	eric@peptidego.com	China	6526	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD	0571-87213919 17306812703	3007955328@qq.com	China	6213	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28118	58

REVERSIN 121
BOC-ASP(OBZL)-LYS(Z)-OTBU
L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester
174630-04-7
C34H47N3O9
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors
Enzyme Inhibitors by Enzyme
P-Glycoprotein
P to Q
Biochemicals and Reagents
BioChemical