tert-Butyl thiophen-2-ylcarbamate
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- CAS-Nr.
- 56267-50-6
- Englisch Name:
- tert-Butyl thiophen-2-ylcarbamate
- Synonyma:
- NSC 263609;AKOS 92405;BUTTPARK 97\57-48;2-(N-Boc-amino)thiophene;TERT-BUTYL 2-THIENYLCARBAMATE;tert-Butyl thien-2-ylcarbamate;2-Aminothiophene, 2-BOC protected;tert-Butyl thiophen-2-ylcarbaMate;TERT-BUTYL N-(2-THIENYL)CARBAMATE;2-Aminothiophene, N-BOC protected
- CBNumber:
- CB8784339
- Summenformel:
- C9H13NO2S
- Molgewicht:
- 199.27
- MOL-Datei:
- 56267-50-6.mol
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tert-Butyl thiophen-2-ylcarbamate Eigenschaften
- Schmelzpunkt:
- 151 °C
- Siedepunkt:
- 238.1±13.0 °C(Predicted)
- Dichte
- 1.186±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- Aggregatzustand
- solid
- pka
- 13.63±0.70(Predicted)
- Farbe
- Pale grey
- InChI
- InChI=1S/C9H13NO2S/c1-9(2,3)12-8(11)10-7-5-4-6-13-7/h4-6H,1-3H3,(H,10,11)
- InChIKey
- QTXXTRMGTVEBIN-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NC1SC=CC=1
tert-Butyl thiophen-2-ylcarbamate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White to off-white crystalline powder
Synthese
To a solution of thiophenecarboxylic acid (0.5 g, 3.90 mmol) in tBuOH (10 ml) was added Et3N (0.571 ml, 4.10 mmol) and DPPA (0.883 ml, 4.10 mmol). The solution was heated at 90 °C for 4 hours. The reaction mixture was cooled to RT, and the solvent was removed from the vacuum. The residue was treated with benzene, and the solution was washed with 5 per cent citric acid and NaHCO3. Solid was filtered off, and the filtrate was washed with brine. The organic layer was dried (MgSO4), concentrated in vacuo and the residue was purified by silica gel column chromatography (EtOAc/hexanes) to obtain tert-butyl thiophen-2-ylcarbamate (0.39 g, 50percent yield). 1H NMR (400 MHz, DMSO-d6): δ 10.4 (brs, 1H), 6.84 (dd, J = 1.6, and 5.2 Hz, 1H), 6.75 (dd, J = 4.0, and 5.6 Hz, 1H), 6.48 (dd, J= 1.6, and 4.0 Hz, 2H), 1.45 (s, 9H); MS (ESI) m/z: 222.0 (M+22+H+).
tert-Butyl thiophen-2-ylcarbamate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
tert-Butyl thiophen-2-ylcarbamate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 137)Lieferanten
56267-50-6()Verwandte Suche:
- TERT-BUTYL N-(2-THIENYL)CARBAMATE
- TERT-BUTYL 2-THIENYLCARBAMATE
- THIOPHEN-2-YL-CARBAMIC ACID TERT-BUTYL ESTER
- BUTTPARK 97\57-48
- AKOS 92405
- tert-Butyl thiophen-2-ylcarbaMate
- CarbaMic acid, N-2-thienyl-, 1,1-diMethylethyl ester
- tert-Butyl thien-2-ylcarbamate
- 2-Aminothiophene, 2-BOC protected
- tert-Butyl (thien-2-yl)carbamate, 2-[(tert-Butoxycarbonyl)amino]thiophene
- NSC 263609
- 2-(N-tert-Butoxycarbonylamino)thiophene
- 2-(N-Boc-amino)thiophene
- tert-ButylN-(2-thienyl)carbamate≥ 96% (NMR)
- 2-Aminothiophene, N-BOC protected
- TERT-BUTYL N-(2-THIENYL)CARBAMATE ISO 9001：2015 REACH
- 56267-50-6
