Bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,4-diphenylcyclobutan-1,3-dicarboxylat, stereoisomer

bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 2,4-diphenylcyclobutane-1,3-dicarboxylate, stereoisomer Struktur

490-17-5

CAS-Nr.: 490-17-5

Bezeichnung:: Bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,4-diphenylcyclobutan-1,3-dicarboxylat, stereoisomer

Englisch Name:: bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 2,4-diphenylcyclobutane-1,3-dicarboxylate, stereoisomer

Synonyma:: α-Truxilline;a-Truxilline;EINECS 207-707-5;2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester;bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 2,4-diphenylcyclobutane-1,3-dicarboxylate, stereoisomer;bis[(1R,2R,3S,5S)-2-methoxycarbonyl-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2,4-di(phenyl)cyclobutane-1,3-dicarboxylate;2,4-di(phenyl)cyclobutane-1,3-dicarboxylic acid bis[(1R,2R,3S,5S)-2-carbomethoxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester;bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl](1r,2c,3t,4t)-2,4-diphenylcyclobutane-1,3-dicarboxylate(α-truxilline)

CBNumber:: CB8913001

Summenformel:: C38H46N2O8

Molgewicht:: 658.78

MOL-Datei:: 490-17-5.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 5

Bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,4-diphenylcyclobutan-1,3-dicarboxylat, stereoisomer Eigenschaften

Schmelzpunkt:: 80°C

Löslichkeit: Chloroform (Slightly), DMSO (Slightly)

Aggregatzustand: Solid

Farbe: Off-White to Pale Yellow

EPA chemische Informationen: 1,3-Cyclobutanedicarboxylic acid, 2,4-diphenyl-, bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester, (1.alpha.,2.alpha.,3.beta.,4.beta.)- (490-17-5)

Sicherheit

Bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,4-diphenylcyclobutan-1,3-dicarboxylat, stereoisomer Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

From the leaves of Erythroxylon truxillense Rusby, Hesse isolated an amorphous alkaloid which he designated Cocamine. This was subsequently shown by Liebermann to be a mixture of two isomeric bases and, although the pure alkaloids have not yet been obtained from the alkaloidal mixture owing to difficulties in their separation, each has been prepared synthetically. This particular alkaloid is an amorphous white powder which is soluble in all organic solvents except light petroleum and also insoluble in H20. Solutions of the base are alllaevorotatory and have an intensely bitter taste. Acid hydrolysis with dilute HCl yields MeOH, (-)-ecgonine and Q-truxillic acid, m.p. 228°C. The alkaloid is synthesized by the action of α-truxillic anhydride on (-)-ecgonine followed by methylation of the resulting α-truxilloylecgonine.

Einzelnachweise

Hesse., Pharm. Zeit., 407,668 (1887)
Liebermann., Ber., 21,2342 (1888)
Hesse., ibid, 22, 665 (1889)
Liebermann, Drory., ibid, 22,682 (1889)

Bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,4-diphenylcyclobutan-1,3-dicarboxylat, stereoisomer Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,4-diphenylcyclobutan-1,3-dicarboxylat, stereoisomer Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 5)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Sichuan BioCrick Biotech Co., Ltd	28-85433893	info@biocrick.com	CHINA	4988	58
Zhuhai Anzhe Biotechnology Co,Ltd.	13169972583	513211116@qq.com	China	3015	58
Shaanxi Dideu Medichem Co. Ltd	029-81124267 15229202216	1073@dideu.com	China	10011	58

a-Truxilline
bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 2,4-diphenylcyclobutane-1,3-dicarboxylate, stereoisomer
EINECS 207-707-5
2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester
2,4-di(phenyl)cyclobutane-1,3-dicarboxylic acid bis[(1R,2R,3S,5S)-2-carbomethoxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester
bis[(1R,2R,3S,5S)-2-methoxycarbonyl-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2,4-di(phenyl)cyclobutane-1,3-dicarboxylate
α-Truxilline
bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl](1r,2c,3t,4t)-2,4-diphenylcyclobutane-1,3-dicarboxylate(α-truxilline)
490-17-5