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(R)-1-N-Boc-2-(hydroxymethyl)piperazine

(R)-1-N-Boc-2-(hydroxymethyl)piperazine Struktur
169448-87-7
CAS-Nr.
169448-87-7
Englisch Name:
(R)-1-N-Boc-2-(hydroxymethyl)piperazine
Synonyma:
Nicotinamide Impurity 202;(R)-1-Boc-2-Hydroxymethyl-piperazine;(R)-1-Boc-2-(hyroxyMethyl)piperazine;(R)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE HCl;(S)-1-Boc-2-Hydroxymethyl-piperazine ,98%;(R)-1-Boc-2-Hydroxymethyl-piperazine ,98%;(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate;tert-butyl (R)-2-(hydroxymethyl)piperazine-1-carboxylate;tert-Butyl (2R)-2-(hydroxymethyl)piperazin-1-carboxylate;tert-Butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
CBNumber:
CB8948025
Summenformel:
C10H20N2O3
Molgewicht:
216.28
MOL-Datei:
169448-87-7.mol
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(R)-1-N-Boc-2-(hydroxymethyl)piperazine Eigenschaften

Siedepunkt:
324.0±17.0 °C(Predicted)
Dichte
1.085±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
14.97±0.10(Predicted)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
HS Code  2933599590
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H332 Gesundheitsschädlich bei Einatmen. Akute Toxizität inhalativ Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P271, P304+P340, P312
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

(R)-1-N-Boc-2-(hydroxymethyl)piperazine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate is used in preparation of novel substituted quinoline-8-carbonitrile derivatives with androgen receptor degradation activity and uses thereof.

Synthese

Lithium aluminum hydride (1M in THF, 26 ml) was added to a solution of L-TERT- butyl 2-methyl (2R)-piperazine-1, 2-dicarboxylate (2. 55 g) in THF (70 ml) at-40°C, and then the reaction was warmed to room temperature. After stirring for 1 h, this reaction system was cooled to 0°C and quenched by sequential addition of water (1 ml), sodium hydroxide (2N, 1 ml), and then water (2 ml). The resulting slurry was filtered and concentrated in vacuo to give (R)-1-N-Boc-2-(hydroxymethyl)piperazine.
(R)-1-N-Boc-2-(hydroxymethyl)piperazine

(R)-1-N-Boc-2-(hydroxymethyl)piperazine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

(R)-N-Boc-piperazine-2-carboxylic acid methyl ester

Downstream Produkte

(R)-1-N-Boc-2-(hydroxymethyl)piperazine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 130)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Boc Chemical Co., Ltd.
021-34975602; +8618721111801
 shangli@bocchem.com China 138 58
Hangzhou FandaChem Co.,Ltd. 		+8615858145714
 FandaChem@Gmail.com China 9206 55
Accela ChemBio Inc. 		+1-858-6993322
info@accelachem.com United States 17453 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873
 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49374 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29811 58
Antai Fine Chemical Technology Co.,Limited 		18503026267
 info@antaichem.com CHINA 9636 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051
 joe@yuhengpharm.com CHINA 21142 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196
 sale04@alfachem.cn China 13415 58
  • (R)-1-Boc-2-Hydroxymethyl-piperazine
  • 1-Piperazinecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2R)-
  • tert-butyl (R)-2-(hydroxymethyl)piperazine-1-carboxylate
  • (R)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE HCl
  • 2-Methyl-2-propanyl(2R)-2-(hydroxymethyl)-1-piperazinecarboxylate
  • (R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate
  • (R)-1-Boc-2-Hydroxymethyl-piperazine ,98%
  • (S)-1-Boc-2-Hydroxymethyl-piperazine ,98%
  • tert-Butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
  • (R)-1-Boc-2-(hyroxyMethyl)piperazine
  • (R)-1-N-Boc-2-(hydroxymethyl)piperazine###(R)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • (2R)-2-(hydroxymethyl)-1-Piperazinecarboxylic acid tert-butyl ester
  • tert-Butyl (2R)-2-(hydroxymethyl)piperazin-1-carboxylate
  • Nicotinamide Impurity 202
  • 169448-87-7
  • 16944-87-7
  • 169448-87-8
  • Piperaizine
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