indigoidine

indigoidine Struktur
2435-59-8
CAS-Nr.
2435-59-8
Englisch Name:
indigoidine
Synonyma:
Indigoidin;Indigoidine;Veretexyn Blue;5,5'-Diamino-Δ3,3'(2H,2'H)-bipyridine-2,2',6,6'(1H,1'H)-tetraone;2,6(1H,3H)-Pyridinedione, 5-amino-3-(5-amino-1,6-dihydro-2,6-dioxo-3(2H)-pyridinylidene)-;5-Amino-3-(5-amino-1,2,3,6-tetrahydro-2,6-dioxopyridin-3-ylidene)-2,6(1H,3H)-pyridinedione
CBNumber:
CB92334234
Summenformel:
C10H8N4O4
Molgewicht:
248.19
MOL-Datei:
2435-59-8.mol

indigoidine Eigenschaften

Siedepunkt:
285.6±40.0 °C(Predicted)
Dichte
1.637±0.06 g/cm3(Predicted)
pka
5.88±0.40(Predicted)

Sicherheit

indigoidine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Indigoidine is a blue-violet organic pigment related to the Azaquinones group and synthesized by bacterial strains. It is biosynthesized by bacterial species such as Streptomyces chromofuscus,E. coli,and Corynebacterium insidiosum (Gangulyet al. 2019). It is used as a food colorant in cereal, baking, and ice-cream industries.

Verwenden

Indigoidine natural blue dye is a promising alternative to the synthetic dyes used to colored jeans, leather, food, beverages, cosmetics and paper. The blue color of the indigoidine compound is bright and sustainable. As a natural dye, it has promising health benefits as an antioxidant and antimicrobial actor. Because of a new purification process patented with the compound, indigoidine natural blue dye is safe to use in food and drinks.

Definition

ChEBI: Indigoidine is a member of the class of pyridone that is a dimeric blue pigment biosynthesised from L-glutamine. It has a role as a bacterial metabolite and a biological pigment. It is a pyridone, a ring assembly, a dicarboximide and an enamine. It derives from a L-glutamine.

Biosynthese

Indigoidine is a water-insoluble blue pigment that was first isolated from phytopathogenic Erwinia as a powerful radical scavenger that enables phytopathogens to tolerate oxidative stress, organic peroxides, and superoxides during the plant defense response due to its structure of carbon–carbon double bonds conjugated with a carbonyl group. This bacterial pigment shows a bright blue color similar to that of indigo. Several different strains are reported to produce it. Indigoidine is assembled from two units of L-glutamine by a nonribosomal peptide synthetase (e.g. IndC from Erwinia chrysanthemi and Streptomyces aureofaciens CCM 3239, BpsA from Streptomyces lavendulae and Sc-indC from Streptomyces chromofuscus ATCC 49982) (Figure 1.7b). Recently, an indigoidine biosynthetic gene cluster was located in the genome of S. chromofuscus ATCC 49982. The gene cluster is silent and consists of five open reading frames, called orf1, Sc-indC, Sc-indA, Sc-indB, and orf2. Sc-IndC was functionally characterized as an indigoidine synthase through heterologous expression of the enzyme in both Streptomyces coelicolor CH999 and E. coli BAP1. The titer of indigoidine in E. coli BAP1 was reported to be 2.78 g/L under optimized conditions. Its production was dramatically increased (by 41.4%/3.93 g/L) when Sc-IndB was co-expressed with it in E. coli BAP1 (Yu et al. 2013). In order to further improve production, a glutamine synthetase gene was amplified from E. coli and co-expressed with Sc-indC and Sc-indB in E. coli BAP1. At 2.5 mM (NH4)2HPO4, the titer can reach 7.08±0.11 g/L (Xu et al. 2015). This provides a green, efficient production process for this promising blue dye.

Solubility in water

Indigoidine is found in two redox states, an oxidized blue form which is insoluble in water and a reduced colorless form which is water soluble and historically referred to as leucoindigoidine[1].

indigoidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


indigoidine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 7)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ROSEWA HOLDING GROUP CO.,LIMITED
+86-023-62871537
sales@rosewachem.com China 2850 58
Hubei Wande Chemical Co., Ltd 027-59210159 15377098680
1148280011@qq.com China 9978 58
Jiangsu Runfeng Synthetic Technology Co., Ltd. 0513-66017678 18551497631
507167383@qq.com China 4724 58
Hubei DAHAO Chemical Co., Ltd. 027-59106191 13986034860
1400828855@qq.com China 9689 58
Wuhan beileye Biomedical Technology Co., Ltd 18086118076
1784708432@qq.com China 4150 58
jinkui(taizhou)technology co ltd 18969655221
530532315@qq.com China 207 58
Guangdong Wengjiang Chemical Reagent Co.,Ltd. 0751-2815983 13927872582
3008325437@qq.com China 2335 58

2435-59-8()Verwandte Suche:


  • 5,5'-Diamino-Δ3,3'(2H,2'H)-bipyridine-2,2',6,6'(1H,1'H)-tetraone
  • 5-Amino-3-(5-amino-1,2,3,6-tetrahydro-2,6-dioxopyridin-3-ylidene)-2,6(1H,3H)-pyridinedione
  • Indigoidin
  • Indigoidine
  • 2,6(1H,3H)-Pyridinedione, 5-amino-3-(5-amino-1,6-dihydro-2,6-dioxo-3(2H)-pyridinylidene)-
  • Veretexyn Blue
  • 2435-59-8
  • 2345-59-8
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