N-[[[(1S)-1-CARBOXY-3-METHYLBUTYL]AMINO]CARBONYL]-L-GLUTAMIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden
Biologische Aktivität
Potent inhibitor of glutamate carboxypeptidase II and III (GCP II and III/NAAG peptidase/NAALADase) (K i values are 0.8 and 23 nM respectively) that inhibits the hydrolysis of NAAG (IC 50 = 2.4 nM) . Does not directly interact with NMDA or metabotropic glutamate receptors. Reduces neuronal degeneration in a rat model of? traumatic brain injury (TBI) and reduces locomotor activity in the PCP-model of schizophrenia.
N-[[[(1S)-1-CARBOXY-3-METHYLBUTYL]AMINO]CARBONYL]-L-GLUTAMIC ACID Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte