Anti-Transcription factor a, mitochondrial Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Rabbit Anti-TFAM (AB1) antibody can be used for western blotting applications at 0.25μg/ml.
Allgemeine Beschreibung
Mitochondrial transcription factor A (TFAM) belongs to the high mobility group proteins and is required for mitochondrial DNA (mtDNA) maintenance. Studies have reported that human mtDNA is packed with TFAM.
Rabbit Anti-TFAM (AB1) antibody recognizes bovine, canine, human, mouse, and pig TFAM.
Biochem/physiol Actions
TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Anti-Transcription factor a, mitochondrial Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
