4-(2-Hydroxyethyl)-1-piperazinpro-pansulfonsäure

16052-06-5

CAS-Nr.: 16052-06-5

Bezeichnung:: 4-(2-Hydroxyethyl)-1-piperazinpro-pansulfonsäure

Englisch Name:: HEPPS

Synonyma:: HEPE;EPPS;aEPPS;HEPPS;EPPS,99%;HEPPS(EPPS);HEPPS Buffer;EPPS USP/EP/BP;EPPS SIGMAULTRA;HEPPS ULTRAPURE

CBNumber:: CB9310937

Summenformel:: C9H20N2O4S

Molgewicht:: 252.33

MOL-Datei:: 16052-06-5.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 357

4-(2-Hydroxyethyl)-1-piperazinpro-pansulfonsäure Eigenschaften

Schmelzpunkt:: 237-239 °C(lit.)

Dichte: 1.2684 (rough estimate)

Brechungsindex: 1.6800 (estimate)

storage temp.: Sealed in dry,Room Temperature

Löslichkeit: H₂O: 1 M at 20 °C, clear, colorless

Aggregatzustand: Powder/Solid

Farbe: White

PH: 5.0-6.5 (25℃, 0.1M in H2O)

pka: 8.0(at 25℃)

Säure-Base-Indikators(pH-Indikatoren): 7.3 - 8.7

Wasserlöslichkeit: Soluble in water. 25.2 g/L (20°C)

maximale Wellenlänge (λmax): λ: 260 nm Amax: 0.055
λ: 280 nm Amax: 0.045

BRN: 3957385

CAS Datenbank: 16052-06-5(CAS DataBase Reference)

EPA chemische Informationen: 1-Piperazinepropanesulfonic acid, 4-(2-hydroxyethyl)- (16052-06-5)

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38-22
S-Sätze:	24/25-36-26
WGK Germany	3
RTECS-Nr.	TM2649130
TSCA	Yes
HazardClass	IRRITANT
HS Code	29335995
Toxizität	quail,LD50,oral,> 316mg/kg (316mg/kg),Ecotoxicology and Environmental Safety. Vol. 6, Pg. 149, 1982.

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H302	Gesundheitsschädlich bei Verschlucken.	Akute Toxizität oral	Kategorie 4	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P270, P301+P312, P330, P501
H315	Verursacht Hautreizungen.	Hautreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P302+P352, P321,P332+P313, P362
H319	Verursacht schwere Augenreizung.	Schwere Augenreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P305+P351+P338,P337+P313P
H332	Gesundheitsschädlich bei Einatmen.	Akute Toxizität inhalativ	Kategorie 4	Warnung	src="/GHS07.jpg" width="20" height="20" />	P261, P271, P304+P340, P312
H335	Kann die Atemwege reizen.	Spezifische Zielorgan-Toxizität (einmalige Exposition)	Kategorie 3 (Atemwegsreizung)	Warnung	src="/GHS07.jpg" width="20" height="20" />

Sicherheit

P280	Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338	BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P310	Sofort GIFTINFORMATIONSZENTRUM/Arzt/ anrufen.

4-(2-Hydroxyethyl)-1-piperazinpro-pansulfonsäure Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Chemische Eigenschaften

white crystalline powder

Verwenden

HEPPS (EPPS) is a commonly used Good's buffer. It is often used as separator in ultrathin isoelectric focusing gels and enhances the resolution of phosphoglucomutase. It is used as a buffering agent in biology and biochemistry. HEPPS is a biological buffer with a useful pH range of 7.3-8.7 and a pKa=8.0 at 25°C. Research on mice with Alzheimer's disease-like amyloid beta plaques has shown that HEPPS can cause the plaques to break up, reversing some of the symptoms in the mice. HEPPS was reported to dissociate amyloid beta oligomers in patients' plasma samples enabling blood diagnosis of Alzheimer's disease.

Allgemeine Beschreibung

HEPPS, or N-(2-Hydroxyethyl)piperazine-N′-(3-propanesulfonic acid), is a zwitterionic buffering agent commonly used in biochemical and molecular biology research. Its mechanism of action is rooted in its ability to maintain a stable pH environment, which is crucial for various enzymatic reactions and protein studies. HEPPS is especially favoured for its buffering capacity in the physiological pH range, typically between pH 6.8 and 8.2, making it ideal for biological assays and cell culture experiments. This compound is extensively utilized in preparing cell culture media, where maintaining a consistent pH is essential for cell viability and growth. Additionally, HEPPS is employed in biochemical assays, such as enzyme kinetics studies, where precise pH control is necessary to accurately measure enzymatic activity. Furthermore, HEPPS has found applications in molecular biology techniques, including nucleic acid purification, PCR (polymerase chain reaction), and protein analysis by SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis). Its compatibility with various biological systems and stability under physiological conditions make HEPPS a valuable tool in research laboratories for maintaining optimal pH conditions and ensuring reliable experimental outcomes in various biochemical and molecular biology studies.

4-(2-Hydroxyethyl)-1-piperazinpro-pansulfonsäure Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4-(2-Hydroxyethyl)-1-piperazinpro-pansulfonsäure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 357)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hubei Yiling biotechnology Co Ltd	+86-18163349544 +86-18163349544	mollylucking@foxmail.com	China	480	58
Suzhou Genemill Biotechnology Co.,Ltd	+8615862502491	aimeegao@genemill.com	China	39	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12459	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	973	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3002	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	16216	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21670	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55

16052-06-5(4-(2-Hydroxyethyl)-1-piperazinpro-pansulfonsäure)Verwandte Suche:

Natrium-2-hydroxyethansulfonat 4-(2-Hydroxyethyl)piperazin-1-ylethansulfonsure Piperazin Hydroxyethyl Cellulose 1-Ethylpiperazin Folsure Calciumdobesilat 2-(Methylsulfonyl)ethanol Zitronensure 2-Hydroxyethansulfonsure Natriumethylensulfonat 2-Ethylpiperazine 2-Piperazin-1-ylethylamin 2-Piperidinoethanol Hydroxyethyl starch 2-Piperazin-1-ylethanol ASCORBICACID β-Hydroxy-4-(2-hydroxyethyl)piperazin-1-propansulfonsure

HEPPS(EPPS)
4-(2-Hydroxyethyl)pi
HEPE
3-[4-(2-HYDROXYETHYL)-1-PIPERAZINE]PROPANESULFONIC ACID
3-[4-(2-HYDROXYETHYL)-1-PIPERAZINYL]PROPANESULFONIC ACID
N-(2-HYDROXYETHYL)-N'-(3-SULFOPROPYL)-PIPERAZINE
N-[2-HYDROXYETHYL]PIPERAZINE-N'-[3-PROPANESULFONIC ACID]
N-2-HYDROXYETHYLPIPERAZINE-N'-3-PROPANESULPHONIC ACID
aEPPS
HEPPS N-(2-Hydroxyethyl)piperazine-N-3-propanesulfonic acid
HEPPS, ULTROL Grade
HEPPS~4-(2-Hydroxyethyl)-1-piperazinepropanesulphonic acid
EPPS FREE ACID, BIOTECHNOLOGY PERFORMANC E CERTIFIED
EPPS, 99% (4-(2-HYDROXYETHYL)-1-PIPERAZI NE -PROPANESULFONIC ACID)
EPPS SIGMAULTRA
HEPPS CELL CULTURE REAGENT CRYSTALLINE
EPPS 99% (4-(2-HYDROXYETHYL)-1-PIPERAZINE -PROPANESULFONIC ACID) 99+% ULTRA PURE BUFFER GRADE
EPPS, for biochemistry, 99%
Hydroxyethyl)piperazine-N'-3-propane-sulfonic acid
1-Piperazinepropanesulfonic acid, 4-(2-hydroxyethyl)-
4-(2-hydroxyethyl)-1-piperazinepropanesulphonic acid
N-(hydroxyethyl)piperazine-N’-propanesulfonic acid (HEPPS)
4-(2-HYDROXYETHYL)-1-PIPERAZINEPROPANESULFONIC ACID EPPS
HEPPS ULTRAPURE
HEPPS (4-(2-HYDROXYETHYL)PIPERAZINE-1-PROPANESULFONIC ACID)
4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic Acid
HEPPS/EPPS/HEPE
4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid[HEPPS]
HEPPS 3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonic Acid
4-Hydroxyerhylpiperazine-1-propanesulfonic acid
EPPS,99%
EPPS Vetec(TM) reagent grade, 99%
HEPPS/ 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid
4-(2-hydroxyethyl)-1-piperazinepropanesulfonicaci
EPPS
HEPPS
LABOTEST-BB LT00138110
4-(2-HYDROXYETHYL)-1-PIPERAZINEPROPANESULFONIC ACID
4-(2-HYDROXYETHYL)PIPERAZINE-1-PROPANESULFONIC ACID
N-(2-Hydroxyethyl)piperazine-N'-3-propanesulphonic acid >99%
4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic Acid [Good's buffer component for biological research]
Epps, 99%, for biochemistry
HeppsN-(2-Hydroxyethyl)Piperazine-NPropanesulfonicAcid
Epps(N-[2-Hydroxyethyl]Piperazine-N3-PropaneSulfonicAcid])
3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid
3-[4-(2-Hydroxyethyl)piperazine-1-yl]-1-propanesulfonic acid
3-[4-(2-Hydroxyethyl)piperazino]-1-propanesulfonic acid
4-(2-Hydroxyethyl)-1-piperazinepropane-1-sulfonic acid
HEPPS Buffer
4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid, 4-(2-Hydroxyethyl)piperazine-1-propanesulfonic acid, HEPPS, N-(2-Hydroxyethyl)piperazine-Nμ-(3-propanesulfonic acid)
3-[4-(2-Hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid
[2-hydroxyethyl]piperazine-n’-[3-propancesulfonicacid]
N-(Hydroxyethyl)piperazine-N'-propane sulfonic acid
3-(4-(2-Hydroxyethyl)piperazin-1-yl)propane-1-sulfonic
N-(2-Hydroxyethyl)piperazine-N'-(propanesulphonic acid)
HEPPS, ≥99.0%(T)
HEPPS, ≥99.5%(T)
4-(2-HYDROXYETHYL)PIPERAZINE-1-PROPANESULFONIC ACID;EPPS