BTS

BTS Struktur
1576-37-0
CAS-Nr.
1576-37-0
Englisch Name:
BTS
Synonyma:
BTS;CLN3;Battenin;NSC 37123;N-Tosylbenzylamine;N-Benzyl-p-tosylaMide;LABOTEST-BB LT00786416;N-Tosylphenylmethanamine;N-Tosylbenzenemethaneamine;n-benzyl-p-toluenesulfonamid
CBNumber:
CB9457528
Summenformel:
C14H15NO2S
Molgewicht:
261.34
MOL-Datei:
1576-37-0.mol

BTS Eigenschaften

Schmelzpunkt:
115 °C
Siedepunkt:
419.1±48.0 °C(Predicted)
Dichte
1.204±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit
Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly)
Aggregatzustand
White crystalline solid
pka
11.54±0.30(Predicted)
Farbe
White to Off-White
Sensitive 
Light Sensitive
CAS Datenbank
1576-37-0(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
RTECS-Nr. XT5490000
HS Code  2935.90.9500
Toxizität rat,LD,oral,> 500mg/kg (500mg/kg),National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 41, 1953.
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

BTS Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

BTS is an inhibitor of skeletal muscle myosin II ATPase activity that reduces the affinity of ADP-myosin for actin. It inhibits calcium-stimulated ATPase activity of rabbit muscle myosin subfragment 1 (S1) in an actin-independent manner with an IC50 value of approximately 5 μM. It is selective for calcium-stimulated myosin II over human platelet myosin II, kinesin, pyruvate kinase, and lactate dehydrogenase at 100 μM. BTS (2 μM) inhibits the activity of skeletal muscle myosin, reversibly reducing the sliding velocity of heavy meromyosin in a gliding-filament assay. It inhibits isometric calcium-activated tension in isolated fast-twitch rabbit psoas muscle fibers (IC50 = ~3 μM) but not in isolated slow-twitch rat trabeculae and papillary cardiac muscle. BTS is also an intermediate in the synthesis of sulfonamides.

Chemische Eigenschaften

White Solid

Verwenden

A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II

Biologische Aktivität

Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC 50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.

BTS Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


BTS Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 136)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20324 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32760 60
Accela ChemBio Inc.
(+1)-858-699-3322
info@accelachem.com United States 19965 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29826 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
sales@tnjchem.com China 34571 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6313 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739
info@dycnchem.com China 52861 58
Hebei Duling International Trade Co. LTD
+8617333973358
sales01@hbduling.cn China 15437 58
TargetMol Chemicals Inc.
+1-781-999-5354
support@targetmol.com United States 19973 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490
info@gihichemicals.com China 49999 58

1576-37-0()Verwandte Suche:


  • n-benzyl-p-toluenesulfonamid
  • N-BENZYL-P-TOLUENESULFONAMIDE
  • N-BENZYL-P-TOLUENESULPHONAMIDE
  • LABOTEST-BB LT00786416
  • BTS
  • 4-METHYL-N-(PHENYLMETHYL)BENZENESULFONAMIDE
  • N-BENZYL-4-METHYL-BENZENESULFONAMIDE
  • N-Tosylbenzylamine
  • N-Methyl-N-(phenylmethyl)benzenesulfonamide
  • N-Tosylbenzenemethaneamine
  • N-Tosylphenylmethanamine
  • Benzyl(4-toluenesulfonyl)aMine
  • N-Benzyl-p-tosylaMide
  • NSC 37123
  • ANTI-CLN3 (CENTER) antibody produced in rabbit
  • Battenin
  • CLN3
  • 4-methyl-n-(phenylmethyl)-benzenesulfonamid
  • N-Benzyl-p-ToluenesulfonaMide (BTS)
  • BTS - CAS 1576-37-0 - Calbiochem
  • Benzenesulfonamide,4-methyl-N-(phenylmethyl)-
  • BTS (N-Benzyl-p-toluenesulfonamide
  • N-Benzyl-p-toluenesulfonamide >
  • 1576-37-0
  • A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~5 μM) and reversibly blocks the gliding motility.
  • Inhibitors
  • ATPase
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