Procathepsin K, Human, Recombinant, E. coli

Procathepsin K, Human, Recombinant, E. coli Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Recombinant, human procathepsin K (amino acids 19-329) (GenBank target symbol = S79895, ACC No. P43235) expressed in E. coli with a methionine residue inserted at amino acid 18 to create a new N-terminal initiation site. Cathepsin K, a member of the papain superfamiliy of cysteine proteinases, plays an important role in osteoclast-mediated bone resorption and collagen degradation. Cathepsin K is synthesized as an inactive proenzyme that is converted to its mature, active form by proteolytic cleavage of the 99 amino acid propeptide domain. Inhibitors of cathepsin K include leupeptin (Cat. No. 108975) (IC₅₀ = 70 nM), E-64 (Cat. No. 324890) (IC₅₀ = 5 nM), and cystatin (Cat. No. 324891 or 324896). Requires activation prior to use.

Procathepsin K, Human, Recombinant, E. coli Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Procathepsin K, Human, Recombinant, E. coli Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

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• Procathepsin K, Human, Recombinant, E. coli