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Dimethylamine Hcl

CAS No.
506-59-2
Chemical Name:
Dimethylamine Hcl
Synonyms
METHANAMINE HYDROCHLORIDE;DMACl;DIMETHYLAMINE HCL;DIMETHYLAMMONIUM CHLORIDE;DiMethylaMine hydrochlorid;Metformin EP Impurity F HCl;JACS-506-59-2;Dimethylamine hydroc;Imatinib EP Impurity I;Dacarbazine Impurity 3
CBNumber:
CB00124562
Molecular Formula:
C2H8ClN
Molecular Weight:
81.54
MDL Number:
MFCD00012477
MOL File:
506-59-2.mol
Last updated:2024-10-25 23:13:37

Dimethylamine Hcl Properties

Melting point 170-173 °C(lit.)
Boiling point 95.79°C (rough estimate)
Density 0.8949 (rough estimate)
vapor pressure <0.1 hPa (25 °C)
refractive index 1.4202 (estimate)
storage temp. Store below +30°C.
solubility H2O: soluble0.5g/10 mL
form Crystalline Powder or Crystals
color White to off-white
PH 5 (100g/l, H2O, 20℃)
Water Solubility 3000 g/L (20 ºC)
Sensitive Hygroscopic
Merck 14,3228
BRN 3589311
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey IQDGSYLLQPDQDV-UHFFFAOYSA-N
LogP -3.28
CAS DataBase Reference 506-59-2(CAS DataBase Reference)
FDA UNII 7M4CWB6AOK
EPA Substance Registry System Methanamine, N-methyl-, hydrochloride (506-59-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P264-P270-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36/37-37/39-36
WGK Germany  1
RTECS  IQ0220000
3-9
TSCA  Yes
HS Code  29211190
Toxicity LD50 in mice (g/kg): 1.21 i.v., 2.00 s.c. (Hazard); LC50 in mice (ppm): 7650 (48 hr), 4725 (14 day); in rats (ppm): 4540 (6 hr) (Steinhagen)
NFPA 704
1
2 0

Dimethylamine Hcl price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.03052 Dimethylammonium chloride for synthesis 506-59-2 5G $25 2024-03-01 Buy
Sigma-Aldrich 8.03052 Dimethylammonium chloride for synthesis 506-59-2 250g $42.8 2024-03-01 Buy
Sigma-Aldrich 8.03052 Dimethylammonium chloride for synthesis 506-59-2 1kg $98.9 2024-03-01 Buy
Sigma-Aldrich 8.03052 Dimethylammonium chloride for synthesis 506-59-2 25kg $1650 2024-03-01 Buy
Sigma-Aldrich 126365 Dimethylamine hydrochloride 99% 506-59-2 5g $23 2024-03-01 Buy
Product number Packaging Price Buy
8.03052 5G $25 Buy
8.03052 250g $42.8 Buy
8.03052 1kg $98.9 Buy
8.03052 25kg $1650 Buy
126365 5g $23 Buy

Dimethylamine Hcl Chemical Properties,Uses,Production

Description

Dimethylamine hydrochloride is the raw material of organic synthesis, the catalyzer of analysis as an acetylize, and the preparation of azoviolet and dimethylamine aqueous solution. Dimethylamine hydrochloride deoxidation is very capable, and corrodibility is vital, so be usually used in cleaning-type soldering flux. Preparation technology is for slowly splashing into hydrochloric acid in dimethylamine for tradition, and the speed that splashes into is no more than 15 ℃ with temperature, and pH=7-8 is limited. After the reaction finishes, activated carbon decolorizing is added, the filtrate is adjusted to pH=3-4 with hydrochloric acid, decompression is steamed water to the greatest extent, obtaining dimethylamine hydrochloride.

Chemical Properties

White, foliage-like crystals with a melting point of 171°C. Highly soluble in water, soluble in alcohol and chloroform, and insoluble in ether. Exhibits deliquescence.

Uses

Dimethylamine hydrochloride is used as an intermediate in the manufacture of pharmaceuticals like ranitidine and metformin, tramadol and amlodipine. It is used as a precursor of atrazine. It is associated with sodium acetate and used to carry out the Willgerodt- Kindler reaction to prepare amides. Its free base reacts with carbon disulfide to get dimethyldithiocarbamate which is used in rubber vulcanization. It is involved in the synthesis of dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine by reacting with 1-methyl pyrrole and formaldehyde.

Uses

Dimethylamine hydrochloride is a precursor to several industrially significant compounds.

Uses

As accelerator in vulcanizing rubber, tanning, manufacture of detergent soaps, or attracting boll weevils to exterminate them. As reagent for Mg.

Preparation

Dimethylamine hydrochloride is obtained from the salt formation of dimethylamine and hydrochloric acid.

Application

Dimethylamine hydrochloride serves as a foundational material for organic synthesis and is utilized as a catalyst and magnesium reagent in acetylation analysis. It has been used in producing hexamethylmelamine-methyl-14C and in preparing standard solutions of methylamine (MA), dimethylamine (DMA), trimethylamine (TMA), and trimethylamine-N-oxide (TMAO) to assess the presence of methylamines and trimethylamine-N-oxide in particulate matter.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise the salt from hot CHCl3 or absolute EtOH. It also recrystallises from MeOH/ether solution. Dry it in a vacuum desiccator over H2SO4, then P2O5. Hygroscopic. [Beilstein 4 IV 132.]

124-40-3
506-59-2
Synthesis of Dimethylamine Hcl from Dimethylamine
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