ChemicalBook >> CAS DataBase List >>Trimethoprim-Sulfamethoxazole
Trimethoprim-Sulfamethoxazole
- CAS No.
- 8064-90-2
- Chemical Name:
- Trimethoprim-Sulfamethoxazole
- Synonyms
- TMP-SMX;SMZ/TMP;Septrim;Chemitrim;Trimforte;Trimethoprimsulfa;Co-Trimoxazole (CTX), 95%;Trimethoprim-Sulfamethoxazole;Sulfamethoxazole/Trimethoprim;TRIMETHOPRIM/SULPHAMETHOXAZOLE
- CBNumber:
- CB00125566
- Molecular Formula:
- C24H29N7O6S
- Molecular Weight:
- 543.6
- MDL Number:
- MOL File:
- 8064-90-2.mol
Last updated:2024-12-18 13:37:16
| storage temp. | -20°C |
|---|---|
| solubility | DMF: 10mg/mL,DMSO: 10mg/mL,DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL,Ethanol: 0.3mg/mL |
| form | liquid |
| color | colorless to faint yellow |
| BCS Class | 4/4 |
| NCI Dictionary of Cancer Terms | trimethoprim-sulfamethoxazole |
| NCI Drug Dictionary | trimethoprim-sulfamethoxazole |
| EPA Substance Registry System | Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, mixt. with 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine (8064-90-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H317-H319-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-43 |
| Safety Statements | 26-36/37 |
| WGK Germany | 3 |
| RTECS | UV8240000 |
| Hazardous Substances Data | 8064-90-2(Hazardous Substances Data) |
| Toxicity | LD50 orally in mice: 5513 mg/kg (Yamamoto) |
Trimethoprim-Sulfamethoxazole price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A2487 | Cotrimoxazole, Ready Made Solution | 8064-90-2 | 1ml | $619 | 2024-03-01 | Buy |
| TRC | C725300 | Cotrimoxazole | 8064-90-2 | 2.5g | $185 | 2021-12-16 | Buy |
| TRC | C725300 | Cotrimoxazole | 8064-90-2 | 10g | $520 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004695 | CO-TRIMOXAZOLE 95.00% | 8064-90-2 | 5MG | $550 | 2021-12-16 | Buy |
| AK Scientific | 1199CC | Sulfamethoxazoleandtrimethoprim | 8064-90-2 | 5g | $761 | 2021-12-16 | Buy |
Trimethoprim-Sulfamethoxazole Chemical Properties,Uses,Production
Uses
Cotrimoxazole is an antibiotic. Pseudomonas aeruginosa has a drug resistant rate of 66% in the years 2010-2013.
World Health Organization (WHO)
The combination of sulfamethoxazole and trimethoprim (5:1) was introduced in 1971 for the treatment of a wide variety of bacterial infections. Its use has been associated with severe sensitivity reactions, many of which have been attributed to the sulphonamide component. Elderly people seem to be more vulnerable. The World Health Organization has no information further to the above concerning restrictive action taken on this combination.
Side effects
Trimethoprim/sulfamethoxazole on a daily basis has a rapid onset of action
but has rare associated side effects of bone marrow suppression and toxic
epidermal necrolysis (TEN).
Nausea, vomiting, and anorexia are generally dose related.
Hypersensitivity reactions (including Stevens-Johnson syndrome and hematologic
reactions) occur in <5% of patients.
Dosage forms
One to two tablets a day. Trimethoprim is dosed at 200 mg/24 hours given either q.d. or b.i.d.
Trimethoprim-Sulfamethoxazole Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19741 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19885 | 58 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
| Shandong Mopai Biotechnology Co., Ltd | 13070690626 | admin@mopaikeji.com | China | 10757 | 58 |
| Shaanxi Istare Biotechnology Co., Ltd. | 18682931470 | 2142355700@qq.com | China | 4564 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19704 | 58 |
View Lastest Price from Trimethoprim-Sulfamethoxazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-25 | Sulfamethoxazole
723-46-6
|
US $15.00 / kg | 1kg | 99.912% | 10ton | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2022-01-21 | Sulfamethoxazole
723-46-6
|
US $10.00 / Kg/Bag | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd | |
 |
2019-07-06 | Sulfamethoxazole
723-46-6
|
US $8.00 / kg | 1kg | 99% | 10MT | Career Henan Chemical Co |
-
- Sulfamethoxazole
723-46-6
- US $15.00 / kg
- 99.912%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- Sulfamethoxazole
723-46-6
- US $10.00 / Kg/Bag
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
-
- Sulfamethoxazole
723-46-6
- US $8.00 / kg
- 99%
- Career Henan Chemical Co
8064-90-2(Trimethoprim-Sulfamethoxazole)Related Search:
SMZ/TMP
Sulfamethoxazole/Trimethoprim
Trimethoprim-Sulfamethoxazole Combination
TRIMETHOPRIM/SULPHAMETHOXAZOLE
Chemitrim
Septrim
Cotrimoxazole, Ready Made Solution
TMP-SMX
Trimethoprim-Sulfamethoxazole
Co-Trimoxazole (CTX), 95%
Trimethoprimsulfa
Trimforte
5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine mixture with 4-amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide
8064-90-2