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Bromhexine

CAS No.
3572-43-8
Chemical Name:
Bromhexine
Synonyms
bromhexine;BroMhexine IMpurity E;Auxit;Na 274;Bromexine;Aids001646;Aids-001646;BROMOHEXINE;AKOS B015997;AURORA KA-7546
CBNumber:
CB00125747
Molecular Formula:
C14H20Br2N2
Molecular Weight:
376.13
MDL Number:
MFCD00436295
MOL File:
3572-43-8.mol
MSDS File:
SDS
Last updated:2024-07-19 18:29:52

Bromhexine Properties

Melting point 238℃
Boiling point 413.8±40.0 °C(Predicted)
Density 1.57
storage temp. 2-8°C(protect from light)
solubility DMSO: 75 mg/mL (199.40 mM);Ethanol: 75 mg/mL (199.40 mM)
pka 8.34±0.20(Predicted)
Water Solubility Water: Insoluble
FDA UNII Q1J152VB1P
ATC code R05CB02

SAFETY

Risk and Safety Statements

Signal word  Warning
Hazard statements  H410-H400
Precautionary statements  P273-P391-P501-P273-P391-P501
Toxicity Approx LD50 orally in rabbits: >10 g/kg (Boyd, Sheppard)

Bromhexine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0007117 N-(2-AMINO-3,5-DIBROMOBENZYL)-N-CYCLOHEXYL-N-METHYLAMINE 95.00% 3572-43-8 1G $477.38 2021-12-16 Buy
American Custom Chemicals Corporation API0027098 BROMHEXINE IMPURITY E 95.00% 3572-43-8 5MG $502.8 2021-12-16 Buy
American Custom Chemicals Corporation API0007117 N-(2-AMINO-3,5-DIBROMOBENZYL)-N-CYCLOHEXYL-N-METHYLAMINE 95.00% 3572-43-8 25G $1422.46 2021-12-16 Buy
American Custom Chemicals Corporation API0007117 N-(2-AMINO-3,5-DIBROMOBENZYL)-N-CYCLOHEXYL-N-METHYLAMINE 95.00% 3572-43-8 50G $2392.25 2021-12-16 Buy
Chemenu CM201336 2,4-dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline 95% 3572-43-8 1g $580 2021-12-16 Buy
Product number Packaging Price Buy
API0007117 1G $477.38 Buy
API0027098 5MG $502.8 Buy
API0007117 25G $1422.46 Buy
API0007117 50G $2392.25 Buy
CM201336 1g $580 Buy

Bromhexine Chemical Properties,Uses,Production

Description

Bromhexine is a mucolytic agent that decreases sputum thickness. In order to enable the patient to breathe freely and deeply, it is used to treat conditions characterized by abnormal mucus secretion, such as the common cold, respiratory tract infections and influenza. Because of the elevated risk of serious side effects, it should be used with caution in patients who have a history of gastric ulcers. Bromhexine improves mucus transport by lowering mucus viscosity and stimulating the ciliated epithelial layer (mucociliary clearance). Cough is relieved and the expectoration is made easier by secretolytic and secretomotor effects in the bronchial tract.

Uses

Bromhexine is a drug that aids the body's mucus-clearing processes in the respiratory tract. It is used to relieve chest congestion. The medication belongs to a class of drugs called mucolytics, which break down mucus to make it easier to cough up. As a result, to treat cough, this medication is added to cough syrups. In order to prevent chest congestion, mucus in the respiratory tract should be expelled on a regular basis. Bromhexine can help the body's natural mechanisms to remove inflammation by expelling mucus. Bromhexine is a mucolytic.

Mechanism of action

Bromhexine works by lowering mucous viscosity. It will be accompanied by a rise in lysosomal activity. The hydrolysis of acid mucopolysaccharide polymers will be accelerated if the lysosomal activity is increased. This can lead to normal mucus viscosity. The mucous viscosity in the bronchus would be higher if you have purulent bronchial inflammation. The presence of a significant amount of DNA in the mucus is the basis for the mucus. Coughing can increase in the beginning as Bromhexine breaks down the mucous.

Side effects

Some of the common and major side effects of Bromhexine are:
Irritation of ear; Allergic skin rash; Dizziness; Headache; Diarrhea; Difficulty while breathing; Rash; Sweating; Vomiting; Headache; Respiratory tract infection; Throat infection.

Precautions

Before using Bromhexine talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other serious problems. Before taking the drug talk with your doctor if you have any medical history such as peptic ulceration, asthma, kidney disease, stomach disease, stomach ulcer, abdominal pain and severe hepatic or renal impairment.

Bromhexine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 65)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387 1057@dideu.com China 3921 58
airuikechemical co., ltd.
+undefined86-15315557071 sales06@airuikechemical.com China 983 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177 sarah@tnjone.com China 1143 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21668 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32760 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10326 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 info@afinechem.com China 15395 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923 1026@dideu.com China 8722 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58

View Lastest Price from Bromhexine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Bromhexine pictures 2024-04-10 Bromhexine
3572-43-8
US $0.00-0.00 / mg 10mg 90%+ 10g Guangzhou PI PI BIOTECH INC
bromhexine pictures 2024-04-03 bromhexine
3572-43-8
US $0.00-0.00 / g 1g 99.99% 20 tons airuikechemical co., ltd.
bromhexine pictures 2021-08-12 bromhexine
3572-43-8
US $900.00 / KG 1KG 99 20tons Shanghai Dumi Biotechnology Co.,ltd
  • Bromhexine pictures
  • Bromhexine
    3572-43-8
  • US $0.00-0.00 / mg
  • 90%+
  • Guangzhou PI PI BIOTECH INC
  • bromhexine pictures
  • bromhexine
    3572-43-8
  • US $0.00-0.00 / g
  • 99.99%
  • airuikechemical co., ltd.
  • bromhexine pictures
  • bromhexine
    3572-43-8
  • US $900.00 / KG
  • 99
  • Shanghai Dumi Biotechnology Co.,ltd
AKOS B015997 BROMOHEXINE AURORA KA-7546 ART-CHEM-BB B015997 Auxit 32184-12-6 (X Hydrochloride) 611-75-6 (Hydrochloride) Aids001646 Aids-001646 BROMHEXINE, PHARMA 2,4-Dibromo-6-((cyclohexyl(methyl) N-2-AMINO-3,5-DIBROMOBENZYL-N-CYCLOHEXYLMETHYLAMINE 2,4-Dibromo-6-([cyclohexyl(methyl)amino]methyl)aniline 2-Amino-3,5-dibromo-N-cyclohexyl-N-methyl benzenemethanamine 2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzenemathanamine Benzenemethanamine, 2-amino-3,5-dibromo-N-cyclohexyl-N-methyl- Bromexine Na 274 Toluene-alpha,2-diamine, 3,5-dibromo-Nalpha-cyclohexyl-Nalpha-methyl- N-(2-amino-3,5-dibromobenzyl)-N-cyclohexyl-N-methylamine BROMOHEXINE USP/EP/BP bromhexine BroMhexine IMpurity E Bromhexine HCL Base 3572-43-8 208538-73-3 C14H20Br2N2