ChemicalBook >> CAS DataBase List >>Mesalamine
Mesalamine
- CAS No.
- 89-57-6
- Chemical Name:
- Mesalamine
- Synonyms
- MESALAZINE;MESALAMINE;5-ASA;5-AMINO-2-HYDROXYBENZOIC ACID;Asacol;rowasa;3-Carboxy-4-hydroxyaniline;Canasa;Pentasa;Mesalmine
- CBNumber:
- CB00126613
- Molecular Formula:
- C7H7NO3
- Molecular Weight:
- 153.14
- MDL Number:
- MFCD00007877
- MOL File:
- 89-57-6.mol
- MSDS File:
- SDS
Last updated:2024-08-24 19:19:26
| Melting point | 275-280 °C (dec.) (lit.) |
|---|---|
| Boiling point | 276.03°C (rough estimate) |
| Density | 1.3585 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5500 (estimate) |
| Flash point | 279-281°C |
| storage temp. | 2-8°C |
| solubility | Soluble in dimethyl sulfoxide. |
| pka | 2.74, 5.84(at 25℃) |
| form | tablets |
| color | off-white to gray |
| PH | 4.0-4.1 (0.8g/l, H2O, 20℃) |
| PH Range | Non-B uorescence (3.1) to light green B uorescence (4.4) |
| Water Solubility | <0.1 g/100 mL at 21 ºC |
| Decomposition | 279-281 ºC |
| Merck | 14,5904 |
| BRN | 2090421 |
| BCS Class | 4 |
| Stability | Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents. |
| Major Application | Detergent, hair dyes, prevention of colorectal cancer, treating inflammatory bowel disease, autoimmune disorders, gastrointestinal inflammation, chemokine-mediated diseases, mucosal tissue disorder, sleep disorders, rectoanal tenesmus, ulcerative colitis |
| InChIKey | KBOPZPXVLCULAV-UHFFFAOYSA-N |
| LogP | 0.98 at 25℃ |
| CAS DataBase Reference | 89-57-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 4Q81I59GXC |
| NCI Drug Dictionary | Asacol |
| ATC code | A07EC02 |
| NIST Chemistry Reference | Mesalamine(89-57-6) |
| EPA Substance Registry System | Benzoic acid, 5-amino-2-hydroxy- (89-57-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P305+P351+P338-P261-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-52/53 | |||||||||
| Safety Statements | 26-36-24/25-61-37/39 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | VO1400000 | |||||||||
| F | 8-10-23 | |||||||||
| Autoignition Temperature | 280 °C | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29225000 | |||||||||
| Toxicity | LD50 orally in Rabbit: 2800 mg/kg LD50 dermal Rat > 5000 mg/kg | |||||||||
| NFPA 704 |
|
Mesalamine price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | BP1075 | Mesalazine British Pharmacopoeia (BP) Reference Standard | 89-57-6 | 125MG | $257 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1392705 | Mesalamine United States Pharmacopeia (USP) Reference Standard | 89-57-6 | 200mg | $436 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.20095 | 5-Amino-2-hydroxybenzoic acid for synthesis | 89-57-6 | 250g | $97.3 | 2022-05-15 | Buy |
| Sigma-Aldrich | 18858 | 5-Aminosalicylic acid analytical standard | 89-57-6 | 100mg | $55.2 | 2021-12-16 | Buy |
| TCI Chemical | A0317 | 5-Aminosalicylic Acid >98.0%(T) | 89-57-6 | 25g | $27 | 2024-03-01 | Buy |
Mesalamine Chemical Properties,Uses,Production
Description
Mesalamine (me SAL a meen) treats ulcerative colitis. It may also be used to prevent flare-ups once your symptoms are controlled. It works by decreasing inflammation in the digestive tract. It belongs to a group of medications called salicylates.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
Uses
Mesalamine is used to treat and prevent flare-ups of mild to moderately active ulcerative colitis (an inflammatory bowel disease). It works inside the bowels to reduce inflammation and other symptoms of the disease.
Side effects
Serious side effects requiring immediate reporting to your healthcare team may include:
- Allergic reactions: such as skin rash, itching, hives, or swelling of the face, lips, tongue, or throat
- Respiratory issues: including dry cough, shortness of breath, or difficulty breathing
- Cardiac complications: like unusual weakness or fatigue, chest pain, rapid or irregular heartbeat, dizziness, or swelling of the ankles, feet, or hands
- Kidney problems: indicated by decreased urine output and swelling of the ankles, hands, or feet, or the presence of kidney stones
- Liver damage: characterized by right upper abdominal pain, loss of appetite, nausea, light-colored stool, dark urine, yellowing of the skin or eyes, or unusual weakness or fatigue
- Mesalamine intolerance syndrome: presenting as stomach pain, cramping, bloody diarrhea, nausea, vomiting, headache, muscle pain, fever, or rash
- Rash, fever, and swollen lymph nodes
- Skin issues: such as redness, blistering, peeling, or loosening of the skin, including inside the mouth
Less serious side effects that may not require immediate medical attention but should be reported if they persist or become bothersome include:
- Diarrhea
- Headache
- Nausea
- Runny or stuffy nose
- Light sensitivity
- Sore throat
- Stomach pain
Mesalamine Preparation Products And Raw materials
Raw materials
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Preparation Products
Benzoic acid, 2-[[1-amino-7-[[4-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sulfo-2-naphthalenyl]azo]-2-methoxyphenyl]azo]-8-hydroxy-3,6-disulfo-2-naphthalenyl]azo]-5-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sul
Sulfasalazine
METHYL 5-AMINOSALICYLATE
BOC-3-AMINOBENZOIC ACID
OLSALAZINE
Benzoic acid, 2-[[1-amino-7-[[4-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sulfo-2-naphthalenyl]azo]-2-methoxyphenyl]azo]-8-hydroxy-3,6-disulfo-2-naphthalenyl]azo]-5-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sul
tetrasodium 2-[[2-amino-6-[[4-[[4-[(3-carboxylato-4-hydroxyphenyl)azo]-7-sulphonato-1-naphthyl]azo]-2,5-dimethoxyphenyl]azo]-5-hydroxy-7-sulphonato-1-naphthyl]azo]-5-nitrobenzoate
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Global( 863)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
| Zhejiang Kinso Technology Co., LTD. | +8619857958369 | sales@kinsopharma.com | China | 47 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5828 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 990 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20294 | 58 |
| Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 265 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 1143 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Related articles
- The Pharmacokinetics and toxicity of Mesalazine
- Mesalazine is a medication commonly used for the treatment of inflammatory bowel disease. Over the years, there has been signi....
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- A useful anti-inflammatory agent: Mesalazine
- Mesalazine is an anti-inflammatory agent, structurally related to salicylates, which is active in inflammatory bowel disease.
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Related Qustion
- Q:What is the Mechanism of action of 5-Aminosalicylic acid
- A:In vitro, 5-ASA shares many pharmacological properties of non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin.
- Aug 19，2024
View Lastest Price from Mesalamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-11 | Mesalamine EP Impurity A
123-30-8
|
US $0.00 / mg | 1mg | above 96% | 50mg | Guangzhou Tosun Pharmaceutical Limited | |
 |
2023-01-31 | 5-Aminosalicylic Acid / Mesalamine / Mesalazine Powder
89-57-6
|
US $57.00 / KG | 25KG | 99% | 200ton | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-01-31 | mesalamine
89-57-6
|
US $52.00 / Kg/Bag | 25Kg/Bag | 99.99% | 200ton | Hebei Mojin Biotechnology Co., Ltd |
-
- Mesalamine EP Impurity A
123-30-8
- US $0.00 / mg
- above 96%
- Guangzhou Tosun Pharmaceutical Limited
-
- 5-Aminosalicylic Acid / Mesalamine / Mesalazine Powder
89-57-6
- US $57.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- mesalamine
89-57-6
- US $52.00 / Kg/Bag
- 99.99%
- Hebei Mojin Biotechnology Co., Ltd
89-57-6(Mesalamine)Related Search:
5-AMINOSALICYLIC ACID
5-AS
LABOTEST-BB LT00134704
IFLAB-BB F1918-0003
BENZOIC ACID, 5-AMINO-2-HYDROXY-
M-AMINOSALICYLIC ACID
5-Amino-2-hydroxybenzoic acid~Mesalamine
5-Aminosalicylic acid;5-Amino-2-hydroxybenzoic acid; 5-ASA
5-Amino-2-Hydroxybenzoic Acid 5-Amino Salicylic Acid
Malasazine
5-Aminosalicylic acid (Mesalazine)
5-AMINOSALICYLIC ACID 100 MG TABLETS,TRU -MEASURE C
5-AMINOSALICYLIC ACID 95-98%
5-AMINOSALICYLIC ACID APPROX 99%
N-AMINOSALICYLIC ACID TABL. APPROX. 10
3&5-AminoSalicylicAcid(MixSalicylicAcid)
5-Aminosalicylicacid,95%
5-Aminosalicylic acid, purified, 99%
MESALAMINE,USP
META-AMINOSALICYLICACID
5-Aminosalicylsure
5-AMINOSALICYLIC ACID 99% USP
5-AMINOSALICYLIC ACID =99%
5-AMINOSALICYLIC ACID USP
5-ASA/5-AS
Mesalazine for system suitability
5-Amino-2-hydroxybenzoic acid for synthesis
Salozinal
5-amino-2-hydroxy-benzoicaci
5-Aminosalicyclic acid
5-amino-salicylicaci
Asacolitin
Claversal
Fisalamine
Lixacol
Mesasal
p-Aminosalicylsaeure
Salicylic acid, 5-amino-
Salofalk
3-Amino-hydroxybenzoicacid
5-Aminosalicylic acid ,98.50%
5-AMINOSALICYLIC ACID, 99%, PURIFIED
5-Aminosalicylic Acid [for Biochemical Research]
5-Aminosalicylic acid ,98.5%
5-Aminosalicylic acid,5-AS, 5-Amino-2-hydroxybenzoic acid, Mesalamine
Mesalamine (200 mg)
5-AMino-2-hydroxybenzene-1-carboxylic acid
5-AMino-2-hydroxybenzoicacid,M-AMinosalicylic acid
5-AMinosalicylic Acid, 99 Percent
5-AMino saliclic acid
NSC 38877
5-Amino-2-hydroxybenzoic Acid
Mesalamine
Mesalazine
5-Amino-2-hydroxybenzoic Acid
5-ASA
Asacolon
Asalit
Ipocol
Mesacol
5-Amino-2-hydroxybenzoic acid, 5-AS, Mesalamine