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Trazodone Hcl

CAS No.
25332-39-2
Chemical Name:
Trazodone Hcl
Synonyms
TRAZODONE HCL;TRAZADONE;Trazodone Hydrochloride Tablets;2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one hydrochloride;kb-831;af1161;tombran;Undepre;BiMaran;Mesyrel
CBNumber:
CB00127703
Molecular Formula:
C19H23Cl2N5O
Molecular Weight:
408.32
MDL Number:
MFCD00079603
MOL File:
25332-39-2.mol
MSDS File:
SDS
Last updated:2024-12-02 17:19:06

Trazodone Hcl Properties

Melting point 223-226?C
Flash point 9℃
storage temp. 2-8°C
solubility 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 23.3 mg/mL
form powder
color off-white
PH pH (10g/l, 25℃) : 3.9~4.5
Water Solubility Soluble at 25mg/ml in methanol. Also soluble in 0.1M HCl or DMSO. Insoluble in water /n
InChIKey OHHDIOKRWWOXMT-UHFFFAOYSA-N
CAS DataBase Reference 25332-39-2(CAS DataBase Reference)
FDA UNII 6E8ZO8LRNM

Pharmacokinetic data

Protein binding 89-95%
Excreted unchanged in urine <5%
Volume of distribution 1-2(L/kg)
Biological half-life 5-13 / -

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H351
Precautionary statements  P280-P301+P312+P330
Hazard Codes  Xn,Xi,T,F
Risk Statements  22-40-36/37/38-39/23/24/25-23/24/25-11
Safety Statements  22-36-37/39-26-45-36/37-16-7
RIDADR  3249
WGK Germany  3
RTECS  XZ5660000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29335990
Toxicity LD50 i.v. in mice: 96 mg/kg (Silvestrini, Quadri)
NFPA 704
0
3 0

Trazodone Hcl price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T-030 Trazodone hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 25332-39-2 1mL $38.1 2024-03-01 Buy
Sigma-Aldrich PHR3372 Trazodone Hydrochloride certified reference material, pharmaceutical secondary standard 25332-39-2 500MG $228 2024-03-01 Buy
Sigma-Aldrich 1673500 Trazodone hydrochloride United States Pharmacopeia (USP) Reference Standard 25332-39-2 200mg $436 2024-03-01 Buy
Alfa Aesar J63070 Trazodone hydrochloride 98+% 25332-39-2 1g $61.65 2024-03-01 Buy
Alfa Aesar J63070 Trazodone hydrochloride 98+% 25332-39-2 5g $234.65 2024-03-01 Buy
Product number Packaging Price Buy
T-030 1mL $38.1 Buy
PHR3372 500MG $228 Buy
1673500 200mg $436 Buy
J63070 1g $61.65 Buy
J63070 5g $234.65 Buy

Trazodone Hcl Chemical Properties,Uses,Production

Description

Trazodone Hcl belongs to the hydrochloride salt form of trazodone with antidepressant and sedative activities, which is primarily used in the treatment of major depression. It is an oral drug that affects the balance of chemicals (neurotransmitters) within the brain that nerves use to communicate with (stimulate) each other.

Uses

Trazodone Hcl serves as a serotonin uptake inhibitor that is effective for patients suffering from major depressive disorders and other subsets of depressive disorders, which is especially helpful for geriatric patients with severe agitation and certain depressive disorders associated with insomnia and anxiety since it has proved that trazodone also has anti-anxiety (anxiolytic) and sleep-inducing (hypnotic) effects. Besides, it is often prescribed as a sedative that is used for the treatment of panic attacks, aggressive behavior, agoraphobia, and cocaine withdrawal in combination with other drugs.

Side effects

Nausea, vomiting, diarrhea, drowsiness, dizziness, tiredness, blurred vision, changes in weight, headache, muscle ache/pain, dry mouth, bad taste in the mouth, stuffy nose, constipation, or change in sexual interest/ability may occur.

19794-93-5
25332-39-2
Synthesis of Trazodone Hcl from Trazodone

Trazodone Hcl Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 347)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Weibang Biotechnology Co., Ltd
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Hebei Mojin Biotechnology Co., Ltd
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Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5889 58
Henan Bao Enluo International TradeCo.,LTD
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Capot Chemical Co.,Ltd.
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Henan Tianfu Chemical Co.,Ltd.
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Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
career henan chemical co
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Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58

View Lastest Price from Trazodone Hcl manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Trazodone pictures 2024-11-19 Trazodone
19794-93-5
US $47.00-72.00 / mg 99.29% 10g TargetMol Chemicals Inc.
Trazodone pictures 2020-01-05 Trazodone
19794-93-5
US $7.00 / KG 1KG 99% 100KG Career Henan Chemical Co
  • Trazodone pictures
  • Trazodone
    19794-93-5
  • US $47.00-72.00 / mg
  • 99.29%
  • TargetMol Chemicals Inc.
  • Trazodone pictures
  • Trazodone
    19794-93-5
  • US $7.00 / KG
  • 99%
  • Career Henan Chemical Co

Trazodone hydrochloride Spectrum

TRAZODONE HYDROCHLORIDE )-onehcl 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-s-triazolo(4,3-a)pyridin-3(2h af1161 kb-831 molipaxin pragmazone thombran tombran 2-[3-[4-(3-CHLOROPHENYL)-1-PIPERAZINYL]PROPYL]-1,2,4-TRIAZOLO-[4,3,A]PYRIDIINE-3(2H)-ONE HYDROCHLORI 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2h)-one hydrochloride 2-[3-[4-(3-CHLOROPHENYL)-1-PIPERAZINYL]PROPYL]-1,2,4-TRIAZOLO-[4,3,A]PYRIDINE-3(2H)-ONE HYDROCHLORIDE 2-[3-[4-(3-chlorophenyl)piperazin-1-y]propyl]-1,2,4-triazolo[4,3-a]pyridine-3(2H)-one hydrochloride 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one TRAZODONEHYDROCHLORIDE,USP TRAZODONE HYDROCHIORIDE TRAZODONE HYDROCHLORIDE USP29/EP5 Undepre Trazodone Hydrochloride (200 mg) Trazodone hydrochloride (Desyrel) BiMaran Mesyrel Trittico 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one,2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-,hydrochloride (1:1) 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one,hydrochloride (1:1) Trazodone hydrochloride 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride Trazodone hydrochloride solution TrazodonHCL Trazodone HCl,trazodone hydrochloride Trazodone (hydrochloride) (CRM) Trazodone Hydrochloride (1.0 mg/mL in Methanol) trazodone hydrochloride: trazodone hcl razodonehydrochloride Trazodone hydrochloride USP/EP/BP Trazodone HCl (AF-116 Trazodone HydrochlorideQ: What is Trazodone Hydrochloride Q: What is the CAS Number of Trazodone Hydrochloride Q: What is the storage condition of Trazodone Hydrochloride Q: What are the applications of Trazodone Hydrochloride Trazodone Hydrochloride (1673500) TRAZODONE HCL TRAZADONE 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one hydrochloride Trazodone Hydrochloride Tablets Trazadone hydrochloride Trazodone hydrochloride in methanol CID 657357 25332-39-2 156-1-11 C19H22C1N5 C19H22ClN5OxHCl C19H22ClN5OHClC19H23Cl2N5 C19H22ClN5OHClC19H23Cl2N5O C19H22ClN5OHCl C19H23Cl2N5O C18H22N5OHCl 40832 Enzymes, Inhibitors, and Substrates Substrates Xenobiotics and Drug Metabolism BioChemical