Biperiden
- CAS No.
- 514-65-8
- Chemical Name:
- Biperiden
- Synonyms
- kl373;KL 373;Akineton;biperiden;Beperiden;bipariden;Akinophyl;Bibristan;Biperidine;BiperidenHcl
- CBNumber:
- CB00130478
- Molecular Formula:
- C21H29NO
- Molecular Weight:
- 311.46106
- MDL Number:
- MFCD05662335
- MOL File:
- 514-65-8.mol
- MSDS File:
- SDS
Melting point | 114°C |
---|---|
Boiling point | 451.49°C (rough estimate) |
Density | 1.0202 (rough estimate) |
refractive index | 1.5614 (estimate) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), DMSO (Slightly,Sonicated), Methanol (Slightly, Sonicated) |
form | Solid |
pka | 14.05±0.29(Predicted) |
color | White to Off-White |
Water Solubility | 25.1 mg/L |
EWG's Food Scores | 1 |
FDA UNII | 0FRP6G56LD |
ATC code | N04AA02 |
NIST Chemistry Reference | Biperiden(514-65-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P280-P305+P351+P338 |
Toxicity | LD50 in mice (mg/kg): 195 s.c., 56 i.v. (Klavehn) |
Biperiden price More Price(11)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | B397820 | Biperiden | 514-65-8 | 50mg | $160 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611544 | Bipariden | 514-65-8 | 50mg | $224.4 | 2021-12-16 | Buy |
AK Scientific | P695 | Biperiden | 514-65-8 | 5mg | $34 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0009339 | BIPERIDEN 95.00% | 514-65-8 | 100MG | $329.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611544 | Bipariden | 514-65-8 | 100mg | $345.1 | 2021-12-16 | Buy |
Biperiden Chemical Properties,Uses,Production
Description
Biperiden has a relatively weak visceral anticholinergic, but a strongnicotinolytic, action in terms of its ability to block nicotineinducedconvulsions. Therefore, its neurotropic action israther low on intestinal musculature and blood vessels.Its action on the eye, althoughmydriatic, is much lower than that of atropine. These weakanticholinergic effects add to its usefulness in Parkinson syndromeby minimizing side effects.
Uses
Biperiden is used alone or together with other medicines (e.g., levodopa) to treat Parkinson's disease. It is also used to control severe muscle reactions.
Brand name
Akineton
Pharmacology
Biperiden has an atropine-like blocking effect on all peripheral structures which are parasympathetic-innervated (e.g. cardiovascular and visceral organs). It also has a prominent central blocking effect on M1 receptors. Biperiden does also act as FIASMA (functional inhibitor of acid sphingomyelinase).
Side effects
Common side effects include blurred vision, dry mouth, sleepiness, constipation, and confusion.
Toxicity
Poison by ingestion,subcutaneous, intraperitoneal, and intravenous routes.When heated to decomposition, it emits toxic fumes ofNOx.
Precautions
Biperiden should not be used in people with a bowel obstruction or glaucoma.It is unclear if use in pregnancy or breastfeeding is safe.
Biperiden Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29900 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34571 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15395 | 58 |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9326 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9821 | 58 |
View Lastest Price from Biperiden manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-08-21 | Sodium tetraborate pentahydrate
12179-04-3
|
1kg | 99% | 100tons | Anhui Ruihan Technology Co., Ltd |
- Sodium tetraborate pentahydrate
12179-04-3
- 99%
- Anhui Ruihan Technology Co., Ltd