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8-Bromotheophylline

CAS No.
10381-75-6
Chemical Name:
8-Bromotheophylline
Synonyms
Nsc164940;AKOS NCG-0005;bromotheophylline;8-Bromotheophyline;8-BROMOTHEOPHYLLINE;LABOTEST-BB LT00134545;Theophylline, 8-bromo-;8-BROMOTHEOPHYLLINE 97%;8-Bromotheophylline >8-Bromotheophylline ,97%
CBNumber:
CB0105862
Molecular Formula:
C7H7BrN4O2
Molecular Weight:
259.06
MDL Number:
MFCD00022664
MOL File:
10381-75-6.mol
MSDS File:
SDS
Last updated:2024-12-18 13:37:16

8-Bromotheophylline Properties

Melting point 295-297°C
Boiling point 469.5±55.0 °C(Predicted)
Density 1.862±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka pKa 5.45±0.1(H2O t=24) (Uncertain)
form Solid
color White to Off-White
BRN 203069
CAS DataBase Reference 10381-75-6
FDA UNII FZG87K1MQ6
EPA Substance Registry System 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl- (10381-75-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312+P330-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501
Risk Statements  20/21/22
Safety Statements  24/25-36/37
RIDADR  2811
HazardClass  6.1(b)
PackingGroup  III
HS Code  29395900

8-Bromotheophylline price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S168378 8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE Aldrich 10381-75-6 50mg $110 2024-03-01 Buy
Sigma-Aldrich 1077708 8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE 10381-75-6 400mg $1310 2024-03-01 Buy
TCI Chemical B3456 8-Bromotheophylline >98.0%(HPLC)(T) 10381-75-6 1g $148 2024-03-01 Buy
TCI Chemical B3456 8-Bromotheophylline >98.0%(HPLC)(T) 10381-75-6 5g $509 2024-03-01 Buy
TRC B688150 8-Bromotheophylline 10381-75-6 10g $690 2021-12-16 Buy
Product number Packaging Price Buy
S168378 50mg $110 Buy
1077708 400mg $1310 Buy
B3456 1g $148 Buy
B3456 5g $509 Buy
B688150 10g $690 Buy

8-Bromotheophylline Chemical Properties,Uses,Production

Description

Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive state since March, 1980. It is also approved by Health Canada to be used alone or in combination with [DB00316] in OTC products.

Chemical Properties

White Crystalline Powder

Uses

The active component in the diuretic Diurex.

Purification Methods

It is purified by dissolving in the minimum volume of dilute NaOH (charcoal), filtering and acidifying to pH ca 3.5-4. The solid that separates is collected, dried in vacuo at 100o and stored in a dark container. It has also been recrystallised from EtOH or AcOH. [Blitz & Beck J Prakt Chem [2] 118 158 1928, Fischer & Ach Chem Ber 28 3142 1895, Beilstein 26 H 476, 26 II 227, 26 III/IV 2447.]

Global( 130)Suppliers
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Capot Chemical Co.,Ltd.
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Accela ChemBio Inc.
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Chongqing Chemdad Co., Ltd
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career henan chemical co
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TargetMol Chemicals Inc.
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Dayang Chem (Hangzhou) Co.,Ltd.
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LEAP CHEM CO., LTD.
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Coresyn Pharmatech Co., Ltd.
+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9984 58

View Lastest Price from 8-Bromotheophylline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
8-Bromotheophylline pictures 2024-11-14 8-Bromotheophylline
10381-75-6
US $29.00 / mL 98.49% 10g TargetMol Chemicals Inc.
8-Bromotheophylline pictures 2021-07-02 8-Bromotheophylline
10381-75-6
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
8-BROMOTHEOPHYLLINE pictures 2020-01-22 8-BROMOTHEOPHYLLINE
10381-75-6
US $1.00 / KG 1KG 98%HPLC 10tons Career Henan Chemical Co
  • 8-Bromotheophylline pictures
  • 8-Bromotheophylline
    10381-75-6
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

8-Bromotheophylline Spectrum

8-bromo-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione AKOS NCG-0005 8-BROMOTHEOPHYLLINE 8-BROMO-3,7-DIHYDRO-1,3-DIMETHYL-1H-PURINE-2,6-DIONE 8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE LABOTEST-BB LT00134545 8-BROMOTHEOPHYLLINE 97% 1,3-Dimethyl-8-bromoxanthine bromotheophylline 8-Bromotheophylline ,97% 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl- 8-Bromotheophyline Nsc164940 Theophylline, 8-bromo- 8-bromo-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione(SALTDATA: FREE) 8-Bromotheophylline (400 mg) 8-BroMo-1,3-diMethyl-1H-purine-2,6(3H,9H)-dione 8-broMo-1,3-diMethyl-1H-purine-2,6(3H,7H)-dione 8-Bromo-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione 8-bromo-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione 8-Bromotheophylline, ≥98% 8-Bromotheophylline > 1H-Purine-2,6-dione, 8-bromo-3,9-dihydro-1,3-dimethyl- 8-Bromotheophylline (1077708) 10381-75-6 C7H7BrN4O2 Pharmaceutical Raw Materials Nucleotides and Nucleosides Bases & Related Reagents Nucleotides