ChicoricAcid

Chicory extract

Cicory acid is a water-soluble phenolic acid compound extracted from the dry whole grass of the Compositae.It is anti-inflammatory, can enhance immune function and induce cell apoptosis. It can also inhibit hyaluronidase and protect collagen from the free radical that can be degraded.

Plant origin

Base source
The dry roots, stems, leaves and flowers of the Compositae.

Plant morphology
Perennial herb, 40~120 cm high, with a gray whiteplant. The root is hypertrophy.Stems are erect, prismatic and hollow. The branches are skewed and  thick at the apex with sparsely coarse hair or sericite and rarely no hair case.The basal leaves and the lower leaves of the stem split in the form ofupside pinniform down to the whole, 5~11 cm long and 1~2 cm wide. Apex lobes are larger and lateral lobes are triangular. Basal part is gradually narrowed into winged petioles; Stem leaves are sessile and the leaves gradually become smaller witha small number. Lanceolate ovate to lanceolate and the upper leaves are small. Below all the leaves are sparsely coarse hair or sericite. For the capitulum inflorescence single stem and branch end, 2~3 will cluster in the upper middle axillary fascicles; Involucre is cylindrical, 8~14 mm long; The outer layer of the involucre is of different shapes and lengths. The length of the length is different. The lower part feels like soft leather with lashes and hairy or non-hairy outside. All the flowers are ligulate and the Corolla is blue. The apex of the achenes is truncated and pappus is short, shaping like Scale and the apex is finely toothed. The flowering period is from July to August, and the fruit period is September.

Habitat and distribution
It grows in the foot of the mountain wetland, the beach barren hills and other places. It is produced in Shenyang, Dalian and other cities.

Figure 1 Chicory

Stability

• The effect of pH value on the stability of chicory acid

• The effect of temperature on the stability

• The effect of metal ions on the stability

• Effect of UV on the stability of chicory acid

• Study on its stability in fruit juice and beverage

• Study on its stability in milk powder

• Study on its stability in jelly

Uses

Chicoric Acid is an effective inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. Also a class of cannabinomimetics with CB2 receptor-dependent and independent

Definition

ChEBI: Chicoric acid is an organooxygen compound. It has a role as a HIV-1 integrase inhibitor and a geroprotector. It is functionally related to a tetracarboxylic acid.

in vivo