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2,6-Dimethoxyphenol

CAS No.
91-10-1
Chemical Name:
2,6-Dimethoxyphenol
Synonyms
MCP;Phenol, 2,6-dimethoxy-;aldrich;Dimethoxyphenol;2,6-Dimethoxyphenyl;2,6-Dimethoxyphenol (syringol);2,6-Dwumetoksyfenol;2,6-dimethoxy-pheno;2,6-Dimethoxyphenol;1,3-dimethylpyrogallate
CBNumber:
CB0112026
Molecular Formula:
C8H10O3
Molecular Weight:
154.16
MDL Number:
MFCD00064434
MOL File:
91-10-1.mol
MSDS File:
SDS
Last updated:2024-11-22 13:59:06

2,6-Dimethoxyphenol Properties

Melting point 50-57 °C(lit.)
Boiling point 261 °C(lit.)
Density 1.1690 (rough estimate)
refractive index 1.4745 (estimate)
FEMA 3137 | 2,6-DIMETHOXYPHENOL
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Crystalline Powder, Crystals, or Crystalline Solid
pka 9.97±0.10(Predicted)
color Off-white or gray to brown
Odor at 1.00 % in dipropylene glycol. smoky phenolic balsamic bacon powdery woody
Odor Type smoky
Water Solubility 2 g/100 mL (13 ºC)
JECFA Number 721
BRN 1526871
InChIKey KLIDCXVFHGNTTM-UHFFFAOYSA-N
LogP 0.77
Substances Added to Food (formerly EAFUS) 2,6-DIMETHOXYPHENOL
CAS DataBase Reference 91-10-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 4UQT464H8K
NIST Chemistry Reference Phenol, 2,6-dimethoxy-(91-10-1)
EPA Substance Registry System Phenol, 2,6-dimethoxy- (91-10-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P301+P312+P330-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36-37/39
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
RTECS  SL0900000
Hazard Note  Irritant
TSCA  Yes
HS Code  29095090
NFPA 704
1
2 0

2,6-Dimethoxyphenol price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W313726 2,6-Dimethoxyphenol natural, ≥96% 91-10-1 100g $435 2024-03-01 Buy
Sigma-Aldrich W313726 2,6-Dimethoxyphenol natural, ≥96% 91-10-1 1kg $2810 2024-03-01 Buy
Sigma-Aldrich W313718 2,6-Dimethoxyphenol ≥98%, FG 91-10-1 100g $138 2024-03-01 Buy
Sigma-Aldrich W313718 2,6-Dimethoxyphenol ≥98%, FG 91-10-1 1kg $604 2024-03-01 Buy
Sigma-Aldrich W313718 2,6-Dimethoxyphenol ≥98%, FG 91-10-1 5kg $2140 2024-03-01 Buy
Product number Packaging Price Buy
W313726 100g $435 Buy
W313726 1kg $2810 Buy
W313718 100g $138 Buy
W313718 1kg $604 Buy
W313718 5kg $2140 Buy

2,6-Dimethoxyphenol Chemical Properties,Uses,Production

Chemical Properties

2,6-Dimethoxyphenol is an off-white or grey to brown crystalline powder that has a woody, medicinal, rather dry odor.

Occurrence

Reported found in beechwood tar creosote, onion, garlic, leek, chive, nira (Allium tuberosum Rotti), nobira (Allium grayi Regal) and caucus (Allium victoralis L.)

Uses

2,6-Dimethoxyphenol has been used as a metabolite of lignin depolymerisation.It is also used as flavoring agent or adjuvant.It is reported to be the single most important flavor chemical in smoke flavors. It is used in smoke flavors, whisky, rum, tea, spice, savory, seafood, meat, liquorices, coffee, and nut flavors.

Preparation

2,6-Dimethoxyphenol is prepared by reacting pyrogallol with methyl iodide in alkaline aqueous medium; by demethylation of pyrogallol trimethyl ether in aqueous alkali or in alcohol.

Definition

ChEBI: 2,6-dimethoxyphenol is a member of the class of phenols that is phenol substituted by methoxy groups at positions 2 and 6. It has a role as a plant metabolite. It is a member of phenols and a dimethoxybenzene.

Aroma threshold values

Detection: 400 ppb to 1.85 ppm

Taste threshold values

Taste characteristics at 60 ppm: sweet, medicinal, creamy, meaty, vanilla, spice.

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 4444, 1979 DOI: 10.1021/jo01338a043
Tetrahedron Letters, 34, p. 7667, 1993 DOI: 10.1016/S0040-4039(00)61534-4

General Description

2,6-Dimethoxyphenol has been identified as one of the volatile flavor constituents in shoyu (soy sauce), wine and wood smoke.

Purification Methods

Purify the phenol by zone melting or sublimation in a vacuum. [Beilstein 6 IV 7329.]

140455-39-6
91-10-1
100-09-4
Synthesis of 2,6-Dimethoxyphenol from Ethanone, 2-(2,6-dimethoxyphenoxy)-1-(4-methoxyphenyl)-
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View Lastest Price from 2,6-Dimethoxyphenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,6-Dimethoxyphenol pictures 2024-11-22 2,6-Dimethoxyphenol
91-10-1
US $1.00 / kg 1kg 99% 10 mt Hebei Weibang Biotechnology Co., Ltd
2,6-Dimethoxyphenol pictures 2024-11-19 2,6-Dimethoxyphenol
91-10-1
US $38.00 / g 97.1% 10g TargetMol Chemicals Inc.
2,6-Dimethoxyphenol pictures 2024-08-08 2,6-Dimethoxyphenol
91-10-1
US $6.00 / kg 1kg 0.99 10000 Hebei Fengjia New Material Co., Ltd
1,3-Dimethoxy-2-hydroxybenzene 1,3-Dimethyl pyrogallate 1,3-dimethylpyrogallate 2,6-dimethoxy-pheno 2,6-Dwumetoksyfenol 2-Hydroxy-1,3-dimethoxybenzene Pyrogallol 1,3-dimethyl ether~Syringol 6-CYCLOHEXYL-4-METHYL PYRONE 2 6-DIMETHOXYPHENOL 98+% 2 6-DIMETHYLPHENOL 96+% NATURAL syringol,2,6-dimethoxyphenol 2,6-Dimethoxyphenol 2,6-DIMETHOXYPHENOL CONGEALED SOLID 2,6-DIMETHOXYPHENOL CRYSTALLINE POWDER 2,6-DiMethoxyphenol, 99% 25GR 2,6-Dimethoxyphenol > 2,6-Dimethoxyphenol USP/EP/BP 2,6-Dimethoxyphenol(Chunk or Granule or Flakes) 2,6-Dimethoxyphenol, ≥96% TIANFU CHEM -- 2,6-Dimethoxyphenol(NATURAL) 2,6-DIMETHOXYPHENOL Extra Pure 2,6-Dimethoxyphenol (syringol) 2,6-Dimethoxyphenyl aldrich Dimethoxyphenol MCP Phenol, 2,6-dimethoxy- Inhibitor,plant,2,6-Dimethoxyphenol,2,6Dimethoxyphenol,inhibit,2,6 Dimethoxyphenol,phenolic compound,substrate,33512 2,6-Dimethoxyphenol in Methanol 91-10-1 1991-10-01 91-10-1;33-51-2 Building Blocks Organic Building Blocks Phenols Oxygen Compounds phenol Flavor Flavor Aromatic Hydrocarbons (substituted) & Derivatives