ChemicalBook >> CAS DataBase List >>4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)-

4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)-

4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)- structure

CAS No.: 934005-36-4

Chemical Name:: 4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)-

Synonyms: Protectin D1 methyl ester;4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)-

CBNumber:: CB012281075

Molecular Formula:: C23H34O4

Molecular Weight:: 374.51

MDL Number:

MOL File:: 934005-36-4.mol

Last updated:2023-06-08 09:03:09

Request For Quotation

4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)- Properties

Boiling point	516.5±50.0 °C(Predicted)
Density	1.014±0.06 g/cm3(Predicted)
solubility	Ethanol: 1 mg/ml
pka	13.75±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Danger

Hazard statements

H225-H319

Precautionary statements

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501

NFPA 704

	3
2		0

4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)- Chemical Properties,Uses,Production

Description

Protectin D1 methyl ester is an esterified form of the specialized pro-resolving mediator protectin D1 . It is an intermediate in the synthesis of protectin D1.¹ Protectin D1 methyl ester (333 μg/kg) reduces infarct area and volume and increases blood vessel density in the tissue surrounding the infarct in a rat model of ischemic stroke induced by middle cerebral artery occlusion (MCAO).²

References

1. Rodriguez, A.R., and Spur, B.W. Total synthesis of the potent anti-inflammatory lipid mediator Protectin D₁ Tetrahedron Lett. 55(43),6011-6015(2014).
2. Bazan, N.G., Eady, T.N., Khoutorova, L., et al. Novel aspirin-triggered neuroprotectin D₁ attenuates cerebral ischemic injury after experimental stroke Exp. Neurol. 236(1),122-130(2012).

4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)- Preparation Products And Raw materials

Raw materials

Preparation Products

4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)- Suppliers

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4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, methyl ester, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)- Protectin D1 methyl ester 934005-36-4