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kauran-16,17-diol

kauran-16,17-diol Structure
kauran-16,17-diol structure
CAS No.
16836-31-0
Chemical Name:
kauran-16,17-diol
Synonyms
ent-kauran;kauran-16,17-diol;ent-kauran-16β,17-diol;ent-Kaurane-16β,17-diol;kauran-16,17-diol, 10 mM in DMSO;Kauran-16,17-diol (ent-Kauran-16beta,17-diol);inhibit,Inhibitor,Apoptosis,kauran16,17diol,kauran 16,17 diol;(4aR,6aS,8R,9S,11aR,11bR)-8-(Hydroxymethyl)-4,4,11b-trimethyltetradecahydro-6a,9-methanocyclohepta[a]naphthalen-8-ol
CBNumber:
CB01308437
Molecular Formula:
C20H34O2
Molecular Weight:
306.48
MDL Number:
MOL File:
16836-31-0.mol
Last updated:2025-04-18 09:51:26
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kauran-16,17-diol Properties

Melting point 193-194 °C
Boiling point 422.3±18.0 °C(Predicted)
Density 1.09±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 14.48±0.60(Predicted)
color White to off-white

kauran-16,17-diol Chemical Properties,Uses,Production

Uses

Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages[1][2].

References

[1] Alvaro Morales, et al. The natural diterpene ent-16β-17α-dihydroxykaurane down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells. Apoptosis. 2011 Dec;16(12):1245-52. DOI:10.1007/s10495-011-0638-5
[2] Nguyen Xuan Nhiem, et al. New ent-kauranes from the fruits of Annona glabra and their inhibitory nitric oxide production in LPS-stimulated RAW264.7 macrophages. Bioorg Med Chem Lett. 2015 Jan 15;25(2):254-8. DOI:10.1016/j.bmcl.2014.11.059

kauran-16,17-diol synthesis

14506-80-0
16836-31-0
Synthesis of kauran-16,17-diol from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

kauran-16,17-diol Preparation Products And Raw materials

Raw materials

Preparation Products

kauran-16,17-diol Suppliers

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3772 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Jiangsu Yongjian Pharmaceutical Co.,Ltd 		+86-0523-80183620 +86-17701422015 982552664@qq.com China 258 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38630 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Mensura Group Limited 		+8618109034517 1058503172@qq.com China 2900 58
Hubei Danding Pharmaceutical Technology Co., Ltd 		+86-18917019315 +86-13173601896 3582572959@qq.com China 496 58
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6905 55
Supplier Advantage
Chengdu GLP biotechnology Co Ltd 		58
Chengdu Biopurify Phytochemicals Ltd. 		58
TargetMol Chemicals Inc. 		58
Jiangsu Yongjian Pharmaceutical Co.,Ltd 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Mensura Group Limited 		58
Hubei Danding Pharmaceutical Technology Co., Ltd 		58
Chengdu Biopurify Phytochemicals Ltd. 60
Wuhan ChemFaces Biochemical Co., Ltd. 55

View Lastest Price from kauran-16,17-diol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
kauran-16,17-diol pictures 2024-11-19 kauran-16,17-diol
16836-31-0
 US $88.00-388.00 / mg 99.87% 10g TargetMol Chemicals Inc.

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kauran-16,17-diol ent-kauran-16β,17-diol ent-kauran ent-Kaurane-16β,17-diol (4aR,6aS,8R,9S,11aR,11bR)-8-(Hydroxymethyl)-4,4,11b-trimethyltetradecahydro-6a,9-methanocyclohepta[a]naphthalen-8-ol Kauran-16,17-diol (ent-Kauran-16beta,17-diol) inhibit,Inhibitor,Apoptosis,kauran16,17diol,kauran 16,17 diol kauran-16,17-diol, 10 mM in DMSO 16836-31-0