Hydroxyecdysone

Hydroxyecdysone Properties

Melting point	242-244 °C
Boiling point	498.63°C (rough estimate)
Density	1.0760 (rough estimate)
refractive index	1.5800 (estimate)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	alcohol: soluble
form	powder
pka	14.13±0.70(Predicted)
color	white
Merck	13,3525
BRN	1917578
InChIKey	NKDFYOWSKOHCCO-YPVLXUMRSA-N
SMILES	O[C@@]12CC[C@]([H])([C@](O)(C)[C@H](O)CCC(O)(C)C)[C@]1(CC[C@]1([H])[C@]3(C[C@H](O)[C@H](O)C[C@@]3([H])C(=O)C=C21)C)C \|&1:1,4,6,9,17,20,22,24,26,29,r\|
LogP	-0.270 (est)
CAS DataBase Reference	5289-74-7(CAS DataBase Reference)
FDA UNII	779A7KPL0Y
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS09
Signal word	Warning
Hazard statements	H410
Precautionary statements	P501-P273-P391
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25-36-26
WGK Germany	2
RTECS	FZ8060000
F	10
HS Code	29372900

Hydroxyecdysone price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H5142	20-Hydroxyecdysone ≥93% (HPLC), powder	5289-74-7	5mg	$196	2024-03-01	Buy
Sigma-Aldrich	H5142	20-Hydroxyecdysone ≥93% (HPLC), powder	5289-74-7	10mg	$357	2024-03-01	Buy
Alfa Aesar	J63091	Ecdysterone	5289-74-7	10mg	$213.65	2024-03-01	Buy
Alfa Aesar	J63091	Ecdysterone	5289-74-7	50mg	$768.65	2024-03-01	Buy
Cayman Chemical	16145	20-hydroxy Ecdysone ≥98%	5289-74-7	5mg	$49	2024-03-01	Buy

Product number	Packaging	Price	Buy
H5142	5mg	$196	Buy
H5142	10mg	$357	Buy
J63091	10mg	$213.65	Buy
J63091	50mg	$768.65	Buy
16145	5mg	$49	Buy

Hydroxyecdysone Chemical Properties,Uses,Production

Description

20-Hydroxyecdysone (also known as Ecdysterone) is a hormone-like substance widely found in animals and plants, with a steroid ring at the core of its structure. It has the function of promoting arthropod molting and protecting plants from insects. Studies have shown that when used as a supplement, ecdysterone has a positive effect on human measurements and performance parameters, and is included in the World Anti-Doping Agency's banned list, but it has recently been found that there is a lack of scientific evidence to support WADA's ban on this substance.

Chemical Properties

White or off-white powder, odorless, hygroscopic, the color gradually becomes darker when exposed to light. Soluble in ethanol, slightly soluble in acetone, slightly soluble in hot water, ethyl acetate, chloroform, almost insoluble in ether, derived from Leulu, Achyranthes bidentata, Cyanotis, arachnoidea, Pfaffia glomerata.

Uses

20-Hydroxyecdysone has been used:
in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
as an insect molting hormone

Definition

ChEBI: 20-hydroxyecdysone is an ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. It has a role as a plant metabolite and an animal metabolite. It is a 20-hydroxy steroid, an ecdysteroid, a 14alpha-hydroxy steroid, a 3beta-sterol, a 2beta-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid and a phytoecdysteroid. It is functionally related to an ecdysone.

Biochem/physiol Actions

20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).

storage

+4°C

Purification Methods

Crystallise -ecdyson from water, tetrahydrofuran/pet ether, MeOH and EtOAc after chromatographic purification. It has max (EtOH) at 240nm ( 12,670 M-1cm-1). [Also IR & NMR: Hüppi & Siddall J Am Chem Soc 89 6799 1967, Kametani et al. Tetrahedron Lett 21 4855 1980, Beilstein 8 IV 343.]

Hydroxyecdysone synthesis

Synthesis of Hydroxyecdysone from turkesterone

Hydroxyecdysone Preparation Products And Raw materials

Raw materials

turkesterone

Preparation Products

20-Hydroxyecdysone 25-acetate

Hydroxyecdysone Suppliers

Global( 561)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.	+86-029-86333380 +86-18829239519	sales06@tgybio.com	China	898	58
Xi'an ZB Biotech Co.,Ltd	+8618591943808	sales01@xazbbio.com	China	815	58
Chengdu Greenpure Biopharma CO.,Ltd	18283602253; +8618283602253	jancyzheng@gcgreenpure.com	China	953	58
Shaanxi LonierHerb Bio Technology Co Ltd	+86-86-+86-86-029-87551862 +8617702909819	sales006@ingredients-lonier.com	China	2639	58
Wuhan Haorong Biotechnology Co.,ltd	+86-18565342920; +8618565342920	sales@chembj.net	China	303	58
Hovane Phytochemicals Co., Ltd	+86-17340288373	victor.liu@hovane.com	China	33	58
Hubei KDG Web Science&Technology Co., Ltd	18672314556 +8618672314556	sales@kdg-tech.com	China	933	58
Hebei Chuanghai Biotechnology Co., Ltd	+86-15531157085 +86-15531157085	abby@chuanghaibio.com	China	8809	58
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12817	58
Sinoway Industrial co., ltd.	0592-5800732; +8613806035118	xie@china-sinoway.com	China	987	58

Supplier	Advantage
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.	58
Xi'an ZB Biotech Co.,Ltd	58
Chengdu Greenpure Biopharma CO.,Ltd	58
Shaanxi LonierHerb Bio Technology Co Ltd	58
Wuhan Haorong Biotechnology Co.,ltd	58
Hovane Phytochemicals Co., Ltd	58
Hubei KDG Web Science&Technology Co., Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Sinoway Industrial co., ltd.	58

View Lastest Price from Hydroxyecdysone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-02	Ecdysone / Ecdysterone 5289-74-7	US $180.00 / kg	1kg	99%	20ton	Hebei Zhuanglai Chemical Trading Co.,Ltd
2025-04-02	Hydroxyecdysone 5289-74-7	US $10.00 / kg	1kg	HPLC 50% 60% 90% 95% 98% UV 70% 80% 90% 95 %	1000 kg	BINBO BIOLOGICAL CO.,LTD
2025-04-02	20-Hydroxyecdysone 5289-74-7	US $0.00-0.00 / Kg	1Kg	98%HPLC	1 ton	Hovane Phytochemicals Co., Ltd

Ecdysone / Ecdysterone
5289-74-7
US $180.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co.,Ltd

Hydroxyecdysone
5289-74-7
US $10.00 / kg
HPLC 50% 60% 90% 95% 98% UV 70% 80% 90% 95 %
BINBO BIOLOGICAL CO.,LTD

20-Hydroxyecdysone
5289-74-7
US $0.00-0.00 / Kg
98%HPLC
Hovane Phytochemicals Co., Ltd

Hydroxyecdysone Spectrum

Hydroxyecdysone(5289-74-7)¹HNMR

5289-74-7(Hydroxyecdysone)Related Search:

β-Ecdysone[20-Hydroxyecdysone] 4'-Hydroxyacetophenone Dehydroepiandrosterone 2'-Hydroxyacetophenone 1-Decen-3-ol

3,7-DIMETHYL-1-OCTEN-3-OL 4-Methyl-3-decen-5-ol 2-Methyl-3-buten-2-ol turkesterone 1-N-PROPYLCYCLOPENTANOL

5-METHYL-2-HEPTEN-4-ONE 2-METHYL-1-PENTEN-3-OL TRANS-2-METHYLCYCLOPENTANOL (S)-1,2-DECANEDIOL 4-METHYL-4-HEPTEN-3-OL

(S)-1,2-OCTANEDIOL Ponesterone A Hydroxyecdysone Ecdysterone

1of4

BETA-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE 7,(5B)-CHOLESTEN-2BETA, 3BETA, 14ALPHA, 20BETA, 22R, 25-HEXOL-6-ONE 2B,3B,14A,20,22[R],25-HEXAHYDROXY-7-CHOLESTEN-6-ONE 2b,3b,14a,20b,22,25-hexahydroxycholest-7-en-6-one 2BETA,3BETA,14ALPHA,20BETA,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-TRIHYDROXY-10,13-DIMETHYL-17-((1R,2R)-1,2,5-TRIHYDROXY-1,5-DIMETHYL-HEXYL)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-6-ONE 20-HYDROXYECDYSON POLYPODINE A 2,3,14,20,22,25-hexahydroxy-,(2-beta,3-beta,5-beta,22r)-cholest-7-en-6-on 2-beta,3-beta,14,20,22,25-hexahydroxy-5-beta-cholet-7-en-6-one 3-beta,14,20,22,25-hexahydroxy-2-bet(22r)-5-beta-cholest-7-en-6-on commisterone crustecdyson SS-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE 20-HYDROXYECDYSONE (B-ECDYSTERONE) β-Ecdysone, Ecdysterone, Insect moulting hormone, Polypodine A, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one Beta Ecdysterone 95% UV, with 70% 20-hydroxyecdysterone Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2b,3b,5b,22R)- Polypodin A Viticosterone 20-beta-ecdysterone 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one β-Ecdysone, Ecdysterone, Insect moulting hormone ECDYSONE, BETA-(RG)(PLEASE CALL) Edysterone Ecdysten 20-Hydroxyecdysone,β-Ecdysone, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one, Ecdysterone, Insect moulting hormone, Polypodine A ECDYSONE, B-(P) 20-Hydroxyedysone (2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-diMethyl-17-((2R,3R)-2,3,6-trihydroxy-6-Methylheptan-2-yl)-2,3,4,5,9,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6(10H)-one 20-Hydroxyecdysone, froM Arachnoides C. B. Clarke B-ecdysone,Commisterone (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-1,2,3,4,5,10,11,12,13,15,16,17-dodecahydro-9H-cyclopenta[a]phenanthren-6(14H)-one 2β,3β,14α,20β,22,25-Hexahydroxycholest-7-en-6-one 20-Hydroxyecdysone, >=95% hydroxyecdysone HYDROXYECDYSONE, 20- INSECT MOULTING HORMONE ECDYSONE, BETA- BETA-ECDYSON isoinokosterone the-7 BETA-ECDYSONE, 99% HPLC BETA-ECDYSONE, 90% UV BETA-ECDYSONE, 95+% β-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE 20-Hydroxyecdysone（β-Ecdysone ） LEVETON 20-OH-ECDYSONE BETAYSONE 20H-ECDYSONE ECDYSONE, BETA-(P) HYDROXYECDYSONE, 20-(SH) BETA-ECDYSONE, 98+% 20-Hydroxyecdysone, 98%, from Arachnoides C. B. Clarke Hydroxyecdysterone professional manufacturer Ecdysterone 5289-74-7