NP 252
- CAS No.
- 132031-81-3
- Chemical Name:
- NP 252
- Synonyms
- NP 252;2,6-Dimethyl-3-cyclopropylaminocarbonyl-4-(o-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid octyl ester
- CBNumber:
- CB01359277
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00874512
- MOL File:
- 132031-81-3.mol
NP 252 Chemical Properties,Uses,Production
Description
NP-252 is a calcium channel antagonist potentially for the treatment of angina pectoris and congestive heart failure. The vasoinhibitory effects of NP-252 were significantly stronger than those of nifedipine in canine cerebral artery. NP-252 (10(-7) and 10(-6) M) dose-dependently attenuated nifedipine-resistant Ca(++)-contraction in the presence of STA2 in both canine cerebral and coronary arteries. The inhibitory effect of combined treatment with NP-252 (10(-6) M) and nitroglycerin (10(-6) M) on nifedipine-resistant Ca(++)-contraction in the cerebral artery was additive. In aorta, only NP-252 reduced total La3+ resistant 45Ca binding. However, the increases in bound 45Ca at La3+ resistant sites and 45Ca unidirectional influx due to KCl were inhibited by both NP-252 and nifedipine.
NP 252 Preparation Products And Raw materials
Raw materials
Preparation Products
NP 252 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 1173954148q | meishipharma@126.com | China | 20035 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 58 |