ETAZOLATE
- CAS No.
- 51022-77-6
- Chemical Name:
- ETAZOLATE
- Synonyms
- SQ 64442;SQ 20009;ETAZOLATE;Zinc00001379;Etazolate hydrochlor;ETAZOLATE HYDROCHLORIDE;1-Ethyl-4-[2-(1-Methylethylidene)hydrazinyl]-;1-Ethyl-4-isopropylidenehydrazino-1H-pyrazolo[3,4-b]-1-pyridine-5-carboxylic Acid Ethyl Ester;1-Ethyl-4-(2-isopropylidenehydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester;1-Ethyl-4-isopropylidenehydrazino- 1H-pyrazolo[3,4-β]-1-pyridine-5-carboxylic Acid Ethyl Ester
- CBNumber:
- CB0140566
- Molecular Formula:
- C14H19N5O2
- Molecular Weight:
- 289.33
- MDL Number:
- MFCD00600136
- MOL File:
- 51022-77-6.mol
- MSDS File:
- SDS
Melting point | 193-194°C |
---|---|
Boiling point | 427.6±55.0 °C(Predicted) |
Density | 1.25±0.1 g/cm3(Predicted) |
storage temp. | Store at RT |
solubility | H2O: >20 mg/mL Solutions should be freshly prepared. |
pka | 9.94±0.70(Predicted) |
form | solid |
color | white |
CAS DataBase Reference | 51022-77-6 |
FDA UNII | I89Y79062L |
ETAZOLATE price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | E889250 | Etazolate | 51022-77-6 | 25mg | $305 | 2021-12-16 | Buy |
Usbiological | 448517 | Etazolate Hydrochloride | 51022-77-6 | 1mg | $326 | 2021-12-16 | Buy |
Usbiological | 255268 | Etazolate hydrochloride | 51022-77-6 | 10mg | $353 | 2021-12-16 | Buy |
Usbiological | E8440 | Etazolate | 51022-77-6 | 10mg | $403 | 2021-12-16 | Buy |
TRC | E889250 | Etazolate | 51022-77-6 | 50mg | $545 | 2021-12-16 | Buy |
ETAZOLATE Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Etazolate Hydrochloride is an acyclic nucleotide phosphodiesterase 4 inhibitor, which also exhibits antidepressant-like activity in acute and chronic mouse and rat model of depression.
Uses
An inhibitor of phosphodiesterase IV, about 8 times more active for cAMP than cGMP.
Uses
PDE inhibitor
Definition
ChEBI: Etazolate is a pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties. It has a role as a neuroprotective agent, an antipsychotic agent, a phosphodiesterase IV inhibitor, an anxiolytic drug, an antidepressant, an alpha-secretase activator and a GABA agent. It is a hydrazone, an ethyl ester and a pyrazolopyridine.
Biological Activity
Phosphodiesterase inhibitor, selective for PDE4 (IC 50 = 2.0 μ M).
ETAZOLATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETAZOLATE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11605 | 64 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35906 | 56 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8072 | 58 |
Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 6463 | 55 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
51022-77-6(ETAZOLATE)Related Search:
1of3