Dimethocaine Hydrochloride
- CAS No.
- 553-63-9
- Chemical Name:
- Dimethocaine Hydrochloride
- Synonyms
- diMethocaine hcl;Larocaine HCl;Larocaine hydrochloride;Dimethylcaine hydrochloride;3-(diethylamino)-2;Dimethyl hydrochloride;Dimethocaine hydrochloride;Dimethocaine/Larocaine hcl;1-Propanol,3-(diethylamino)-2;3-Diethylamino-2,2-dimethylpropyl p-amin...
- CBNumber:
- CB01509593
- Molecular Formula:
- C16H26N2O2.ClH
- Molecular Weight:
- 314.854
- MDL Number:
- MFCD01697031
- MOL File:
- 553-63-9.mol
- MSDS File:
- SDS
Melting point | 195-196℃ |
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storage temp. | Refrigerator |
solubility | DMSO (Slightly), Water (Slightly) |
form | Solid |
color | White to Pale Beige |
InChI | InChI=1S/C16H26N2O2.ClH/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13;/h7-10H,5-6,11-12,17H2,1-4H3;1H |
InChIKey | WWTWKTDXBNHESE-UHFFFAOYSA-N |
SMILES | C1(=CC=C(N)C=C1)C(=O)OCC(C)(C)CN(CC)CC.Cl |
FDA UNII | Z768GH360Q |
SAFETY
Risk and Safety Statements
Toxicity | MLD in mice, rabbits (g/kg): 0.30, 0.15 s.c.; 0.04, 0.015 i.v. (Hirschfelder, Bieter) |
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Dimethocaine Hydrochloride price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 11159 | Dimethocaine (hydrochloride) ≥98% | 553-63-9 | 1mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 11159 | Dimethocaine (hydrochloride) ≥98% | 553-63-9 | 5mg | $270 | 2024-03-01 | Buy |
Cayman Chemical | 11159 | Dimethocaine (hydrochloride) ≥98% | 553-63-9 | 10mg | $477 | 2024-03-01 | Buy |
Usbiological | 010123 | Dimethocaine Hydrochloride | 553-63-9 | 25mg | $460 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0079913 | (3-DIETHYLAMINO-2,2-DIMETHYLPROPYL) 4-AMINOBENZOATE HYDROCHLORIDE 95.00% | 553-63-9 | 25MG | $750.75 | 2021-12-16 | Buy |
Dimethocaine Hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
A local anesthetic with stimulant properties. Studies have shown its potency to be about half that of Cocaine (C633500).
Uses
Dimethocaine Hydrochloride is a local anesthetic, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.[Cayman Chemical]
Application
Dimethocaine Hydrochloride is a drug that belongs to the amide class. It has been shown to have significant effects on neuronal function in vivo, as well as on dopamine neurotransmission in vitro. It is also a substrate for uptake by the dopamine transporter and can inhibit locomotor activity in rats, suggesting it may be a potential therapeutic agent for the treatment of Parkinson's disease. It has been shown to be effective against cocaine addiction and can reduce angiogenic factors in vivo. The drug also interacts with other drugs, including synthetic cannabinoids and amphetamines, which are metabolized by CYP2B6 enzymes. These interactions may result in reduced efficacy of Dimethocaine Hydrochloride therapy.
Side effects
Its positive effects are euphoria, stimulation, increased talkativeness and mood lift. However, because the drug acts similar as cocaine, it has comparable negative side effects. These side effects include: tachycardia, difficulty with breathing, pain on the chest, vasoconstriction, insomnia, paranoia and anxiety.
Dimethocaine Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Guangzhou Tengyue Chemical Co., Ltd. | +86-86-18148706580 +8618826483838 | evan@tyvovo.com | China | 153 | 58 |
Wuhan Aoliqisi New Material Technology Co., Ltd. | +86-13545906766; +8613545906766 | sales@whaop.com | China | 265 | 58 |
Hong Kong Excellence Biotechnology Co., Ltd. | ada@sh-teruiop.com | China | 882 | 58 | |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3582 | 58 |
Wuhan Quanjinci New Material Co.,Ltd. | +8615271838296 | kyra@quanjinci.com | China | 1534 | 58 |
Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | Ethan@dornechem.com | China | 3145 | 58 |
Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | Sara@xmwonderfulbio.com | China | 305 | 58 |
Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | hanson@sdhanjiang.com | China | 975 | 58 |
View Lastest Price from Dimethocaine Hydrochloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-25 | Dimethocaine Hydrochloride
553-63-9
|
US $10.00 / ASSAYS | 1ASSAYS | 99% | 1 ton | Dorne Chemical Technology co. LTD | |
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2024-08-24 | Dimethocaine Hydrochloride
553-63-9
|
US $50.00 / kg | 1kg | 99% | 10000 Kilogram/Kilograms per Day | Hebei Miaoyin Technology Co.,Ltd | |
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2024-08-23 | Dimethocaine HCL
553-63-9
|
US $1.00 / g | 1g | 0.98 | 1000 | Apeloa production Co.,Limited |
-
- Dimethocaine Hydrochloride
553-63-9
- US $10.00 / ASSAYS
- 99%
- Dorne Chemical Technology co. LTD
-
- Dimethocaine Hydrochloride
553-63-9
- US $50.00 / kg
- 99%
- Hebei Miaoyin Technology Co.,Ltd
-
- Dimethocaine HCL
553-63-9
- US $1.00 / g
- 0.98
- Apeloa production Co.,Limited