ChemicalBook >> CAS DataBase List >>N-Methyl-N-(trimethylsilyl)trifluoroacetamide
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
- CAS No.
- 24589-78-4
- Chemical Name:
- N-Methyl-N-(trimethylsilyl)trifluoroacetamide
- Synonyms
- MSTFA;DK232;MSTFA MSTFA;MSTFA Reagent;MSTFA ACTIVATED I;MSTFA+TMCS (99:1);MSTFA ACTIVATED II;MSTFA ACTIVATED III;MSTFA with 1 % TMCS;N-Methyl-N-(trimethy
- CBNumber:
- CB0161574
- Molecular Formula:
- C6H12F3NOSi
- Molecular Weight:
- 199.25
- MDL Number:
- MFCD00000411
- MOL File:
- 24589-78-4.mol
Last updated:2024-08-17 21:30:02
| Melting point | 98-100°C |
|---|---|
| Boiling point | 130132°C |
| Density | 1.075 g/mL at 25 °C(lit.) |
| vapor density | >1 (vs air) |
| vapor pressure | 8.8 mm Hg ( 27 °C) |
| refractive index |
n |
| Flash point | 77 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| pka | -1.34±0.70(Predicted) |
| form | Liquid |
| color | Clear colorless to light yellow |
| Specific Gravity | 1.076 |
| Water Solubility | reacts |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| BRN | 1941550 |
| InChIKey | MSPCIZMDDUQPGJ-UHFFFAOYSA-N |
| CAS DataBase Reference | 24589-78-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| EPA Substance Registry System | Acetamide, 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)- (24589-78-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H315-H319-H335 | |||||||||
| Precautionary statements | P210-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,F,T,N | |||||||||
| Risk Statements | 10-36/37/38-61-50/53-51/53 | |||||||||
| Safety Statements | 26-36-37/39-16-45-53-61 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AC9800000 | |||||||||
| F | 10-21 | |||||||||
| Hazard Note | Flammable | |||||||||
| TSCA | T | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29319090 | |||||||||
| NFPA 704 |
|
N-Methyl-N-(trimethylsilyl)trifluoroacetamide price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.41102 | N-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis | 24589-78-4 | 2ml | $74.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.41102 | N-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis | 24589-78-4 | 5ml | $99.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | M-132 | MSTFA Reagent ampule of 10 × 1.2?mL, analytical standard, Cerilliant? | 24589-78-4 | 10x1.2mL | $144 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.41102 | N-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis | 24589-78-4 | 25mL | $283 | 2024-03-01 | Buy |
| Sigma-Aldrich | 69478 | N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur? | 24589-78-4 | 1mL | $57.2 | 2024-03-01 | Buy |
N-Methyl-N-(trimethylsilyl)trifluoroacetamide Chemical Properties,Uses,Production
Chemical Properties
Clear colorless to light yellow liquid
Uses
A new metabolite of Famprofazone in humans.
Uses
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.
Definition
ChEBI: An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a trimethylsilyl group. N-methyl-N-(trimethylsilyl)trifluoroacetamide is a derivat sation agent used in gas chromatography/mass spectrometry applications.
General Description
N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a derivatizing reagent. It can be used as alternatives to diazomethane.
Purification Methods
Fractionate the amide through a 40mm Vigreux column (p 11). Usually it contains ca 1% of methyl trifluoroacetamide and 1% of other impurities which can be removed by gas chromatography or fractionating using a spinning band column. [Donike J Chromatogr 42 103 1969, Donike J Chromatogr 103 91 1975, Beilstein 4 IV 4011.]
Synthesis of N-Methyl-N-(trimethylsilyl)trifluoroacetamide from N,O-Bis(trimethylsilyl)acetamide and N-Methyl-2,2,2-trifluoroacetamide
N-Methyl-N-(trimethylsilyl)trifluoroacetamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 283)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 662 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18775 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9206 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10310 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
View Lastest Price from N-Methyl-N-(trimethylsilyl)trifluoroacetamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-11 | N-Methyl-N-(trimethylsilyl)trifluoroacetamide
24589-78-4
|
US $5.90-3.20 / kg | 1kg | 99% | 10 tons | Shandong Deshang Chemical Co., Ltd. | |
 |
2024-10-11 | N-Methyl-N- (trimethylsilyl) Trifluoroacetamide
24589-78-4
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2024-08-17 | N-Methyl-N-(trimethylsilyl)trifluoroacetamide
24589-78-4
|
US $6.00 / kg | 1kg | 0.99 | 10000 | Hebei Fengjia New Material Co., Ltd |
-
- N-Methyl-N-(trimethylsilyl)trifluoroacetamide
24589-78-4
- US $5.90-3.20 / kg
- 99%
- Shandong Deshang Chemical Co., Ltd.
-
- N-Methyl-N- (trimethylsilyl) Trifluoroacetamide
24589-78-4
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- N-Methyl-N-(trimethylsilyl)trifluoroacetamide
24589-78-4
- US $6.00 / kg
- 0.99
- Hebei Fengjia New Material Co., Ltd
N-Methyl-N-(trimethylsilyl)trifluoroacetamide Spectrum
N-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)MSN-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)1HNMRN-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)13CNMRN-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)IR1N-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)Raman
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CAS24589-78-4 N-methyl-N-(trimethylsilyl)trifluoroacetamide
N-Methyl-N-Trimethylsilyl Trifluoroacetamide (MSTFA) extrapure, 98%
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MSTFA
N-methyl-N- (trimethylmethyl silane) trifluoroacetamide
DK232
N-Methyl-N- (trimethylsilyl)trifluoroacet
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N-Methyl-N-trimethylsilyltrifluoroacetamide, Trimethylsilylating Agent，≥ 90.0%