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2,4-Diamino-6-hydroxypyrimidine

2,4-Diamino-6-hydroxypyrimidine structure

CAS No.: 56-06-4

Chemical Name:: 2,4-Diamino-6-hydroxypyrimidine

Synonyms: 1956-6-4;2,6-DIAMINOPYRIMIDIN-4-OL;DAHP;2,6-Diaminopyrimidin-4(1H)-one;2,6-DIAMINO-4-PYRIMIDINOL;2,6-diamino-1H-pyrimidin-4-one;2,6-DIAMINO-4-HYDROXYPYRIMIDINE;4(3H)-pyrimidinone, 2,6-diamino-;9-60-9;NSC 9302

CBNumber:: CB0174912

Molecular Formula:: C4H6N4O

Molecular Weight:: 126.12

MDL Number:: MFCD00006098

MOL File:: 56-06-4.mol

Last updated:2024-11-17 19:25:39

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2,4-Diamino-6-hydroxypyrimidine Properties

Melting point	285-286 °C (dec.) (lit.)
Boiling point	234.22°C (rough estimate)
Density	1.3659 (rough estimate)
refractive index	1.7990 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Fine Crystalline Powder
pka	10.61±0.50(Predicted)
color	White to cream
Sensitive	Light Sensitive
Merck	14,2981
BRN	125006
InChIKey	SWELIMKTDYHAOY-UHFFFAOYSA-N
CAS DataBase Reference	56-06-4(CAS DataBase Reference)
FDA UNII	EDH7CNS75I
NIST Chemistry Reference	4(1H)-pyrimidinone, 2,6-diamino-(56-06-4)
EPA Substance Registry System	2,6-Diamino-4(1H)-pyrimidinone (56-06-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

22-24/25-36-26

WGK Germany

Hazard Note

Irritant

TSCA

Yes

HS Code

29335995

NFPA 704

	1
2		0

2,4-Diamino-6-hydroxypyrimidine price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	D1321	2,4-Diamino-6-hydroxypyrimidine >98.0%(HPLC)(T)	56-06-4	25g	$76	2024-03-01	Buy
Alfa Aesar	B21240	2,4-Diamino-6-hydroxypyrimidine, 96%	56-06-4	25g	$28.65	2024-03-01	Buy
Alfa Aesar	B21240	2,4-Diamino-6-hydroxypyrimidine, 96%	56-06-4	100g	$68.65	2024-03-01	Buy
Cayman Chemical	81260	2,4-Diamino-6-hydroxypyrimidine ≥98%	56-06-4	1g	$26	2024-03-01	Buy
Cayman Chemical	81260	2,4-Diamino-6-hydroxypyrimidine ≥98%	56-06-4	5g	$50	2024-03-01	Buy

Product number	Packaging	Price	Buy
D1321	25g	$76	Buy
B21240	25g	$28.65	Buy
B21240	100g	$68.65	Buy
81260	1g	$26	Buy
81260	5g	$50	Buy

2,4-Diamino-6-hydroxypyrimidine Chemical Properties,Uses,Production

Description

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC₅₀ for inhibition of BH₄ biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.

Chemical Properties

White Solid

Uses

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical]

Uses

It stands at the beginning of the enzyme-catalyzed cascade that starts with this seven-carbon carbohydrate and ends with the aromatic amino acids phenylalanine, tyrosine, and tryptophan

Uses

2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.

storage

+4°C

Purification Methods

It recrystallises from H2O. [Beilstein 25 III/IV 3642.]

2,4-Diamino-6-hydroxypyrimidine synthesis

Synthesis of 2,4-Diamino-6-hydroxypyrimidine from Guanidine nitrate and Ethyl cyanoacetate

2,4-Diamino-6-hydroxypyrimidine Preparation Products And Raw materials

Raw materials

Guanidine nitrate Methyl cyanoacetate 2,4-DIAMINO-6-HYDROXY-PYRIMIDINE-5-CARBALDEHYDE 2,4-DIAMINO-6-FLUOROPYRIMIDINE Guanidine hydrochloride

Preparation Products

2,4-DIAMINO-6-MERCAPTOPYRIMIDINE 2,6-DIAMINO-4-METHOXY PYRIMIDINE BENZYL PHENYL SULFIDE 2,4-Diamino-6-hydroxy-5-nitropyrimidine 2,4-DIAMINO-6-ETHOXYPYRIMIDINE

4-Pyrimidinol 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-5-(1-methylethyl)-

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2,4-Diamino-6-hydroxypyrimidine Suppliers

Global( 535)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Hebei Mojin Biotechnology Co.,Ltd	+86-15028179902	angelia@hbmojin.com	China	1177	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29881	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	923	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10310	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58

Supplier	Advantage
Anhui Ruihan Technology Co., Ltd	58
Hebei Mojin Biotechnology Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58

View Lastest Price from 2,4-Diamino-6-hydroxypyrimidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-17	2,4-Diamino-6-hydroxypyrimidine 56-06-4	US $41.00 / mg		99.26%	10g	TargetMol Chemicals Inc.
2024-08-20	2,4-Diamino-6-hydroxypyrimidine 56-06-4	US $0.00 / kg	1kg	99%	50000KG/month	Hebei Mojin Biotechnology Co.,Ltd
2023-09-08	2,4-Diamino-6-hydroxypyrimidine 56-06-4	US $30.00 / kg	1kg	99%	1000t/year	Anhui Ruihan Technology Co., Ltd

2,4-Diamino-6-hydroxypyrimidine
56-06-4
US $41.00 / mg
99.26%
TargetMol Chemicals Inc.

2,4-Diamino-6-hydroxypyrimidine
56-06-4
US $0.00 / kg
99%
Hebei Mojin Biotechnology Co.,Ltd

2,4-Diamino-6-hydroxypyrimidine
56-06-4
US $30.00 / kg
99%
Anhui Ruihan Technology Co., Ltd

2,4-Diamino-6-hydroxypyrimidine Spectrum

2,4-Diamino-6-hydroxypyrimidine(56-06-4)MS 2,4-Diamino-6-hydroxypyrimidine(56-06-4)¹HNMR 2,4-Diamino-6-hydroxypyrimidine(56-06-4)IR1 2,4-Diamino-6-hydroxypyrimidine(56-06-4)IR2

56-06-4(2,4-Diamino-6-hydroxypyrimidine)Related Search:

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4-Hydroxy-6-aminopyrimidine 1-Hydroxyethylidene-1,1-diphosphonic acid 1,3-Diaminoguanidine monohydrochloride Iminodiacetonitrile 4-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester

Methyl 4-(4-oxobutyl)benzoate N-[4-[3-(2,6-DiaMino-1,4-dihydro-4-oxo-5-pyriMidinyl)-3-oxopropyl]benzoyl]-L-glutaMic Acid 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid 3-Buten-1-ol PeMetrexed IMpurity D

PeMetrexed EP IMpurity C Methyl 4-bromobenzoate Benzoic acid, 4-(1-methyl-3-oxopropyl)-, methyl ester (9CI)

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2,4-Diamino-6-hydroxypyrimidine,96% TIMTEC-BB SBB004252 2,4-DIAMINOPYRIMIDIN-6-OL 2,4-DIAMINO-6-HYDROXYPYRIMIDINE 2,4-DIAMINO-6-PYRIMIDINOL 2,4-DIAMINO-6(1H)-PYRIMIDINONE 2,6-DIAMINO-4-PYRIMIDINONE 2,6-DIAMINO-4(1H)-PYRIMIDINONE AURORA KA-376 AKOS MSC-0109 2,6-Diamino-4-Hydroxyprimidine 2-4-DIAMINO6HYDROXY PYRIMID 2,4- two-6- aMinohydroxy pyriMidine 2,4-DiaMino-6-hydroxypyriMidine 96% 2,4-DiaMino-6-hydroxypyriMidine, 97+% InChI=1/C4H6N4O/c5-2-1-3(9)8-4(6)7-2/h1H,(H5,5,6,7,8,9 2,4-Diamino-6-hydroxypyrimidiine 4(1H)-Pyrimidinone, 2,6-diamino- (8CI,9CI) 2,6-Diaminopyrimidin-4-one 6-Aminoisocytosine NSC 44914 NSC 680818 NSC 9302 2,4-Diamino-6-hydroxy 2,4-diaminohypoxanthine 2,6-Diamino-1H-pyrimidin-4-on 2,4-Diamino-6. -Hydroxypyimidine 2,6-DIAMINO-3H-PYRIMIDIN-4-ONE 4(1H)-Pyrimidinone, 2,6-diamino 2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol, 2,6-Diamino-4-pyrimidinone 2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol 2,4-Diamino-6-pyrimidinone 2,6-Diamino-3,4-dihydropyrimidine-4-one 2,6-Diamino-4(3H)-pyrimidinone 2,4-Diamino-6-hydroxypyrimidine,2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol, 2,6-Diamino-4-pyrimidinone 4-DiaMino-6-hydroxypyriMidine 2,4-DIAMINO-6-HYDROXYPYRIDIMIDINE 6-Hydroxy-2,4-diaminopyrimidine 2,4-Diamino-6-hydroxypyrimidine > 2,4-Diamino-6-hydroxypyrimidine ISO 9001：2015 REACH 2,4-Diamino-6-hydroxypyrimidine,56-06-4 NSC 18522 NSC18522 NSC-18522 3-methylidene-1,5-benzodioxepine Pemetrexed Impurity 16 2,6-DIAMINOPYRIMIDIN-4-OL DAHP 2,6-diamino-1H-pyrimidin-4-one 4(3H)-pyrimidinone, 2,6-diamino- 2,6-Diaminopyrimidin-4(1H)-one 1956-6-4 Minoxidil Impurity 19 2,6-DIAMINO-4-PYRIMIDINOL 2,6-DIAMINO-4-HYDROXYPYRIMIDINE 2,4-Diamino-6-hydroxypyrimidine(98.60%) 9-60-9 2.4-Diamino-6-pyrimidone