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L-KAWAIN

L-KAWAIN structure

CAS No.: 500-64-1

Chemical Name:: L-KAWAIN

Synonyms: KAWAIN;gonosan;L-KAWAIN;Nsc112162;(R)-KAWAIN;(R)-(+)-Kavain;Kawain (200 mg);L-KAWAIN USP/EP/BP;(+)-Kavain, 10 mM in DMSO;5,6-Dihydro-4-methoxy-6-styryl-2-pyron

CBNumber:: CB0182759

Molecular Formula:: C14H14O3

Molecular Weight:: 230.26

MDL Number:: MFCD00467093

MOL File:: 500-64-1.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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L-KAWAIN Properties

Melting point	142-148℃
alpha	D20 +105° (abs alc)
Boiling point	bp0.1 195-197°
Density	1.1914 (rough estimate)
refractive index	1.5557 (estimate)
storage temp.	Amber Vial, -20°C Freezer, Under inert atmosphere
solubility	Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form	Solid
color	White to Light Yellow
Stability	Light Sensitive
LogP	0.784 (est)
EWG's Food Scores	1
FDA UNII	W1ES06373M
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes	Xn
Risk Statements	22
HS Code	2932202000

L-KAWAIN price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	26524	Kavain	500-64-1	50mg	$78	2024-03-01	Buy
Cayman Chemical	26524	Kavain	500-64-1	100mg	$139	2024-03-01	Buy
Cayman Chemical	26524	Kavain	500-64-1	10mg	$32	2024-03-01	Buy
TRC	K145700	Kawain	500-64-1	100mg	$160	2021-12-16	Buy
TRC	K145700	Kawain	500-64-1	200mg	$265	2021-12-16	Buy

Product number	Packaging	Price	Buy
26524	50mg	$78	Buy
26524	100mg	$139	Buy
26524	10mg	$32	Buy
K145700	100mg	$160	Buy
K145700	200mg	$265	Buy

L-KAWAIN Chemical Properties,Uses,Production

Originator

Largon,Klinge

Uses

Kawain is a plant extract that shows antioxidant activity through cyclooxygenase enzyme inhibition. May also be active in tumor suppression and apoptotic induction.

Definition

ChEBI: Kawain is a member of 2-pyranones and an aromatic ether.

Manufacturing Process

To 1170 g ethyl acetoacetate at 100-110°C was added a little at time 1605 g bromosuccinimide. After cooling to the mixture was added 300 ml of carbon tetrachloride. From the mixture was isolated ethyl ester of bromoacetoacetic acid which was distilled at 105-125°C/18 mm; yield 67%.
By condensation of the mixture 1400 g ethyl ester of bromoacetoacetic acid, 700 g bromosuccineimide, 500 ml benzene and 350 mg zinc was prepared (R)-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one; melting point 157°C, yield 60-70%.

Therapeutic Function

Anesthetic; Tranquilizer

L-KAWAIN synthesis

Synthesis of L-KAWAIN from trans-Cinnamaldehyde and 2-Butenoic acid, 4-bromo-3-methoxy-, ethyl ester, (2Z)-

L-KAWAIN Preparation Products And Raw materials

Raw materials

N-Bromosuccinimide ZINC Ethyl acetoacetate

Preparation Products

L-KAWAIN Suppliers

Global( 118)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	3772	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29808	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10244	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22854	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Shanghai Standard Technology Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58
Dideu Industries Group Limited	58

View Lastest Price from L-KAWAIN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-17	(+)-Kavain 500-64-1	US $39.00-91.00 / mg		≥95%	10g	TargetMol Chemicals Inc.
2024-09-25	L-KAWAIN 500-64-1	US $0.00-0.00 / mg	5mg	99%	40kg	Wuhan Senwayer Century Chemical Co.,Ltd
2023-02-24	Kawain 500-64-1	US $0.00 / mg	20mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.

(+)-Kavain
500-64-1
US $39.00-91.00 / mg
≥95%
TargetMol Chemicals Inc.

L-KAWAIN
500-64-1
US $0.00-0.00 / mg
99%
Wuhan Senwayer Century Chemical Co.,Ltd

Kawain
500-64-1
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

L-KAWAIN Spectrum

L-KAWAIN(500-64-1)¹HNMR

500-64-1(L-KAWAIN)Related Search:

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BATRACHOTOXIN DL-KAWAIN,KAWAIN 5,6-DIHYDRO-2H-PYRAN-2-ONE 4-phenyl-3-buten-2-ol 5,6-DIHYDRO-4-METHOXY-2H-PYRAN

5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE L-KAWAIN PARASORBICACID

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6-dihydro-4-methoxy-6-styryl-(r)-2h-pyran-2-on gonosan [R-(E)]-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one 5,6-Dihydro-4-methoxy-6-styryl-2-pyron (6R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one (R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, [R-(E)]- 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (+)- 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (R)- Nsc112162 5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one Kawain (200 mg) KAWAIN L-KAWAIN (R)-KAWAIN (r)-5,6-dihydro-4-methoxy-6-styryl-2h-pyran-2-one 4-methoxy-6-(beta-phenylvinyl)-5,6-dihydro-alpha-pyrone 5-hydroxy-3-methoxy-7-phenyl-2,6-heptadienoicacidgamma-lactone (R)-(+)-Kavain 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)- L-KAWAIN USP/EP/BP (R,E)-4-Methoxy-6-styryl-5,6-dihydro-2H-pyran-2-one TIANFU-CHEM_2H-Pyran-2-one,5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)- 500-64-1 γ-Aminobutyric acid Receptor,Calcium Channel,inhibit,Inhibitor,GABA Receptor,Gamma-aminobutyric acid Receptor,Na channels,Sodium Channel,Ca2+ channels,Ca channels,(+)-Kavain,(+) Kavain,Na+ channels,(+)Kavain (+)-Kavain, 10 mM in DMSO 500-64-1 500-61-4 315-48-4 Coumarins Miscellaneous Natural Products