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Propargylglycine

CAS No.
58160-95-5
Chemical Name:
Propargylglycine
Synonyms
propargylglycine;N-2-propyn-1-ylGlycine;Glycine,N-2-propyn-1-yl-;2-(Prop-2-ynylamino)acetic acid;Acetic acid, 2-(prop-2-ynylamino)-
CBNumber:
CB02131126
Molecular Formula:
C5H7NO2
Molecular Weight:
113.11
MDL Number:
MOL File:
58160-95-5.mol
Last updated:2025-04-18 09:51:28

Propargylglycine Properties

Melting point 243 °C (decomp)
Boiling point 273.5±20.0 °C(Predicted)
Density 1.150±0.06 g/cm3(Predicted)
pka 2.18±0.10(Predicted)
form Solid
color Off-white to light yellow
InChI InChI=1S/C5H7NO2/c1-2-3-6-4-5(7)8/h1,6H,3-4H2,(H,7,8)
InChIKey XSJLQGMTIHCDSS-UHFFFAOYSA-N
SMILES C(O)(=O)CNCC#C

Propargylglycine Chemical Properties,Uses,Production

Uses

N-Propargylglycine is an orally active irreversible inhibitor of proline dehydrogenase (PRODH). N-Propargylglycine has antitumor activity and can be used in the study of neurodegenerative diseases[1].

References

[1] Scott GK, et al. N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties. Amino Acids. 2021 Dec;53(12):1927-1939. DOI:10.1007/s00726-021-03012-9

Propargylglycine Preparation Products And Raw materials

Raw materials

Preparation Products

Propargylglycine Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 3978 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 13417589054 trendseenbio@gmail.com China 9070 58
Shanghai Raise Chemical Technology Co.,Ltd 15026594951 rs@raise-chem.com China 3961 55
HBCChem, Inc. +1-510-219-6317 sales@hbcchem.com United States 10648 60
Shanghai Haohong Scientific Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 40109 58
propargylglycine 2-(Prop-2-ynylamino)acetic acid Acetic acid, 2-(prop-2-ynylamino)- N-2-propyn-1-ylGlycine Glycine,N-2-propyn-1-yl- 58160-95-5