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PP3

PP3 structure

CAS No.: 5334-30-5

Chemical Name:: PP3

Synonyms: PP3;Amino d;NSC 1401;PP-3;PP 3;Inetetamab;PP 3, 10 mM in DMSO;PP3 ISO 9001：2015 REACH;PP3, Negative control for PP2;PP3 - CAS 5334-30-5 - Calbiochem;4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE

CBNumber:: CB0230067

Molecular Formula:: C11H9N5

Molecular Weight:: 211.22

MDL Number:: MFCD00022901

MOL File:: 5334-30-5.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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PP3 Properties

Melting point	214-217 °C
storage temp.	-20°C
solubility	DMF, DMSO, Hot methanol
form	Off-white solid
color	Whit to Off-White
λmax	240nm(H2O (pH 1))(lit.)
BRN	198460
CAS DataBase Reference	5334-30-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Codes

Xn,Xi

Risk Statements

36/37/38-22

Safety Statements

36/37/39-26

Hazard Note

Irritant

HS Code

29335995

NFPA 704

	1
2		0

PP3 price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	A2737	4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine >98.0%(HPLC)	5334-30-5	200mg	$38	2024-03-01	Buy
TCI Chemical	A2737	4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine >98.0%(HPLC)	5334-30-5	1g	$118	2024-03-01	Buy
Alfa Aesar	L07125	4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%	5334-30-5	1g	$62.1	2021-12-16	Buy
Alfa Aesar	L07125	4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%	5334-30-5	5g	$227	2021-12-16	Buy
Cayman Chemical	15595	PP3 ≥98%	5334-30-5	1mg	$57	2024-03-01	Buy

Product number	Packaging	Price	Buy
A2737	200mg	$38	Buy
A2737	1g	$118	Buy
L07125	1g	$62.1	Buy
L07125	5g	$227	Buy
15595	1mg	$57	Buy

PP3 Chemical Properties,Uses,Production

Chemical Properties

Whit to Off-White Solid

Uses

Intermediate in the preparation of various enzymatic inhibitors

Uses

The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule inhibitors of this signaling pathway have been developed as a therapeuptic strategy to abate abnormal Src kinase activity. PP3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2 . At concentrations as high as 10 μM, it does not prevent proliferation mediated by a stem cell factor/mast cell growth factor in hematopoietic and cancer cell lines.[Cayman Chemical]

Definition

ChEBI: 1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine is a ring assembly and a member of pyrazoles.

Biological Activity

Negative control for the src kinase inhibitor PP 2 (3-(4-chlorophenyl)1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine ). Inhibits EGFR kinase (IC 50 = 2.7 μ M).

storage

-20°C

PP3 Preparation Products And Raw materials

Raw materials

Preparation Products

PP3 Suppliers

Global( 96)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22854	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.	+8618950047208	ellena@amitychem.com	China	43416	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+8617705817739	info@dycnchem.com	China	53881	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Hubei xin bonus chemical co. LTD	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dideu Industries Group Limited	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58

View Lastest Price from PP3 manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	PP 3 5334-30-5	US $47.00-143.00 / mg		98.92%	10g	TargetMol Chemicals Inc.
2021-12-18	PP3 5334-30-5	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2021-08-12	4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE 5334-30-5	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

PP 3
5334-30-5
US $47.00-143.00 / mg
98.92%
TargetMol Chemicals Inc.

PP3
5334-30-5
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE
5334-30-5
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

5334-30-5(PP3)Related Search:

PP3 1-PHENYLPYRAZOLE (1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YL)-HYDRAZINE NSC4912 BUTTPARK 59\40-21

BUTTPARK 56\40-48 BUTTPARK 127\40-10 BUTTPARK 141\40-58 BUTTPARK 141\40-57 BUTTPARK 127\40-15

4-[4-(4-METHYLPHENYL)PIPERAZIN-1-YL]-1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE BUTTPARK 127\40-02 BUTTPARK 127\40-12 BUTTPARK 127\40-09 BUTTPARK 127\40-07

BUTTPARK 127\40-11 BUTTPARK 127\40-08 BUTTPARK 126\40-99

1of4

4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE 4-AMINO-1-PHENYLPYRAZOLE[3,4-D]PYRIMIDINE 4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE 1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE PP3 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine 4-Amino-1-phenylpyrazolo3,4-düpyrimidine, tech. 85% 4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE: TECH., 85% 4-Amino-1-phenylpyrazole[3,4-d]pyrimidine,95% 4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85% 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine NSC 1401 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, tech PP3 - CAS 5334-30-5 - Calbiochem PP-3;PP 3 PP3 (4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine Amino d 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine > 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-phenyl- PP3 ISO 9001：2015 REACH ErbB-1,Epidermal growth factor receptor,PP3,inhibit,HER1,PP 3,EGFR,PP-3,Inhibitor Inetetamab PP3, Negative control for PP2 PP 3, 10 mM in DMSO 5334-30-5 AMINO Intracellular Signaling Amines Aromatics Heterocycles Intermediates Nucleotides and Nucleosides Bases & Related Reagents Nucleotides